Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF. (Q34624625)

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English	Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF.	scientific article

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9 January 2020

Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF (English)

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9 January 2020

toll-like receptor

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9 January 2020

Alessandro Plebani

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Alessandro Plebani

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Weifeng Xu

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Paul A Santini

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Allysia J Matthews

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April Chiu

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Bing He

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Kang Chen

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Journal of Immunology

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9 January 2020

BAFF and MyD88 signals promote a lupuslike disease independent of T cells

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7 July 2018

Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

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7 July 2018

Airway epithelial cells produce B cell-activating factor of TNF family by an IFN-beta-dependent mechanism

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Dendritic cells: translating innate to adaptive immunity.

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7 July 2018

Hodgkin lymphoma cells express TACI and BCMA receptors and generate survival and proliferation signals in response to BAFF and APRIL

1 reference

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Targeting of somatic hypermutation

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Hyper-IgM syndromes

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7 July 2018

Space, selection, and surveillance: setting boundaries with BLyS.

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7 July 2018

HIV infection: first battle decides the war

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7 July 2018

HIV-1 envelope triggers polyclonal Ig class switch recombination through a CD40-independent mechanism involving BAFF and C-type lectin receptors

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7 July 2018

T-independent type II immune responses generate memory B cells

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7 July 2018

Plasmacytoid dendritic cells and the regulation of immunoglobulin heavy chain class switching.

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7 July 2018

Mucosal immunoglobulins

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7 July 2018

TACI is mutant in common variable immunodeficiency and IgA deficiency

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7 July 2018

Control of lymphocyte development by nuclear factor-kappaB.

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7 July 2018

The role of APRIL and BAFF in lymphocyte activation

1 reference

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7 July 2018

Signaling in B cells via Toll-like receptors

1 reference

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7 July 2018

Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.

1 reference

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7 July 2018

Roles of CD4+ T-cell-independent and -dependent antibody responses in the control of influenza virus infection: evidence for noncognate CD4+ T-cell activities that enhance the therapeutic activity of antiviral antibodies

1 reference

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7 July 2018

IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors

1 reference

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7 July 2018

TACI and BAFF-R mediate isotype switching in B cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Specific NEMO mutations impair CD40-mediated c-Rel activation and B cell terminal differentiation

1 reference

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7 July 2018

Plasmacytoid dendritic cells in immunity

1 reference

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7 July 2018

Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling

1 reference

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7 July 2018

CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

B1b lymphocytes confer T cell-independent long-lasting immunity

1 reference

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7 July 2018

Class-switch recombination: interplay of transcription, DNA deamination and DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Human blood IgM "memory" B cells are circulating splenic marginal zone B cells harboring a prediversified immunoglobulin repertoire

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Induction of protective IgA by intestinal dendritic cells carrying commensal bacteria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

EBV-Encoded Latent Membrane Protein 1 Cooperates with BAFF/BLyS and APRIL to Induce T Cell-Independent Ig Heavy Chain Class Switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Predominant autoantibody production by early human B cell precursors

1 reference

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7 July 2018

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

1 reference

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7 July 2018

The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Toll-like receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Intestinal IgA synthesis: regulation of front-line body defences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Ongoing in vivo immunoglobulin class switch DNA recombination in chronic lymphocytic leukemia B cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

BAFF AND APRIL: a tutorial on B cell survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Dendritic cells, BAFF, and APRIL: innate players in adaptive antibody responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Antibodies, viruses and vaccines

1 reference

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7 July 2018

DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Autoreactivity by design: innate B and T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

A hallmark of active class switch recombination: transcripts directed by I promoters on looped-out circular DNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Bacterial CpG-DNA triggers activation and maturation of human CD11c-, CD123+ dendritic cells.

1 reference

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7 July 2018

Dysregulation of CD30+ T cells by leukemia impairs isotype switching in normal B cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

CD40-CD40L independent Ig gene hypermutation suggests a second B cell diversification pathway in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

A Toll-like receptor recognizes bacterial DNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

T-Independent immune response: new aspects of B cell biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Induction of CD4(+) T-cell-independent immunoglobulin responses by inactivated influenza virus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

B cell memory and the long-lived plasma cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

CD30 is a CD40-inducible molecule that negatively regulates CD40-mediated immunoglobulin class switching in non-antigen-selected human B cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

CD40 ligand and appropriate cytokines induce switching to IgG, IgA, and IgE and coordinated germinal center and plasmacytoid phenotypic differentiation in a human monoclonal IgM+IgD+ B cell line.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Immunity to rotavirus in T cell deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Dendritic cells enhance growth and differentiation of CD40-activated B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Antibody class switching

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Within germinal centers, isotype switching of immunoglobulin genes occurs after the onset of somatic mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Structure and function of natural antibodies.

1 reference

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7 July 2018

CpG motifs in bacterial DNA trigger direct B-cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

7 July 2018

Regulated expression of BAFF-binding receptors during human B cell differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

26 October 2018

Synthetic CpG oligodeoxynucleotides augment BAFF- and APRIL-mediated immunoglobulin secretion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

26 October 2018

Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

26 October 2018

Gut IgA class switch recombination in the absence of CD40 does not occur in the lamina propria and is independent of germinal centers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

26 October 2018

Cutting edge: innate immunity conferred by B cells is regulated by caspase-8.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

26 October 2018

Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

26 October 2018

Th cell-independent immune responses to chimeric hemagglutinin/simian human immunodeficiency virus-like particles vaccine

1 reference

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26 October 2018

CpG DNA redirects class-switching towards "Th1-like" Ig isotype production via TLR9 and MyD88.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

26 October 2018

IgA production without mu or delta chain expression in developing B cells.

1 reference

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26 October 2018

Heterogeneity of tonsillar subepithelial B lymphocytes, the splenic marginal zone equivalents.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

26 October 2018

The evolutionarily conserved sequence upstream of the human Ig heavy chain S gamma 3 region is an inducible promoter: synergistic activation by CD40 ligand and IL-4 via cooperative NF-kappa B and STAT-6 binding sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

26 October 2018

Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3048768

26 October 2018

Normal human IgD+IgM- germinal center B cells can express up to 80 mutations in the variable region of their IgD transcripts

1 reference

https://pubmed.ncbi.nlm.nih.gov/18566393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/18566393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TLR9 signaling in B cells determines class switch recombination to IgG2a

1 reference

https://pubmed.ncbi.nlm.nih.gov/18566393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TLR stimulation modifies BLyS receptor expression in follicular and marginal zone B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18566393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intestinal Bacteria Trigger T Cell-Independent Immunoglobulin A2 Class Switching by Inducing Epithelial-Cell Secretion of the Cytokine APRIL

1 reference

https://pubmed.ncbi.nlm.nih.gov/18566393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-specific mucosal and cellular immunity in HIV-seronegative partners of HIV-seropositive individuals

1 reference

https://pubmed.ncbi.nlm.nih.gov/18566393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-cell-independent antiviral antibody responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/18566393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis and release of B-lymphocyte stimulator from myeloid cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18566393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the T-independent humoral response by TACI

1 reference

https://pubmed.ncbi.nlm.nih.gov/18566393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BLySsful interactions between DCs and B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18566393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18566393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4 T cell-independent antibody response promotes resolution of primary influenza infection and helps to prevent reinfection

1 reference

https://pubmed.ncbi.nlm.nih.gov/18566393

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.181.1.276

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18566393%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

release_zil4rz2yhnf3fdxmndnwqled4q

1 reference

https://api.fatcat.wiki/v0/release/zil4rz2yhnf3fdxmndnwqled4q

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18566393%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18566393%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

ResearchGate publication ID

0 references

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