Epigenetics of discordant monozygotic twins: implications for disease (Q34624829)

3 August 2017

1 reference

title

Epigenetics of discordant monozygotic twins: implications for disease (English)

1 reference

3 August 2017

1 reference

Jordana T Bell

3

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Tim D. Spector

series ordinal

2

object named as

Tim D Spector

1 reference

3 August 2017

Juan E Castillo-Fernandez

series ordinal

1

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3 August 2017

31 July 2014

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3 August 2017

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3 August 2017

6

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3 August 2017

7

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3 August 2017

60

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Creative Commons Attribution 4.0 International

3 August 2017

start time

1 July 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1186/s13073-014-0060-z

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cites work

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7 July 2018

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Reducing the risk of false discovery enabling identification of biologically significant genome-wide methylation status using the HumanMethylation450 array

7 July 2018

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DNA methylation profiles in type 1 diabetes twins point to strong epigenetic effects on etiology

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Distinctive patterns of DNA methylation associated with Parkinson disease: identification of concordant epigenetic changes in brain and peripheral blood leukocytes

7 July 2018

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Monozygotic twins affected with major depressive disorder have greater variance in methylation than their unaffected co-twin

7 July 2018

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Adult monozygotic twins discordant for intra-uterine growth have indistinguishable genome-wide DNA methylation profiles

7 July 2018

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Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance

7 July 2018

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Tobacco smoking leads to extensive genome-wide changes in DNA methylation

7 July 2018

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ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

7 July 2018

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Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits

7 July 2018

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Macro histone variants are critical for the differentiation of human pluripotent cells

7 July 2018

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Developmental timing of mutations revealed by whole-genome sequencing of twins with acute lymphoblastic leukemia

7 July 2018

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Genome-wide DNA methylation analysis in alcohol dependence

7 July 2018

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Epigenetic disruption of the PIWI pathway in human spermatogenic disorders

7 July 2018

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DNA methylation profiling in breast cancer discordant identical twins identifies DOK7 as novel epigenetic biomarker

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Epigenetics and childhood asthma: current evidence and future research directions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

A functional methylome map of ulcerative colitis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Neonatal DNA methylation profile in human twins is specified by a complex interplay between intrauterine environmental and genetic factors, subject to tissue-specific influence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

DNA methylation arrays as surrogate measures of cell mixture distribution

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Epigenetic reprogramming of cancer cells via targeted DNA methylation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

DNA methylation and gene expression changes in monozygotic twins discordant for psoriasis: identification of epigenetically dysregulated genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Coordinated changes in AHRR methylation in lymphoblasts and pulmonary macrophages from smokers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Epigenetics and the environment: emerging patterns and implications

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Monozygotic twins discordant for constitutive BRCA1 promoter methylation, childhood cancer and secondary cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Identification of type 1 diabetes-associated DNA methylation variable positions that precede disease diagnosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Extensive variation and low heritability of DNA methylation identified in a twin study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Tobacco-smoking-related differential DNA methylation: 27K discovery and replication

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Hydralazine and magnesium valproate as epigenetic treatment for myelodysplastic syndrome. Preliminary results of a phase-II trial

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Epigenetic differences in cortical neurons from a pair of monozygotic twins discordant for Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Epigenetics lessons from twins: prospects for autoimmune disease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Lessons from BWS twins: complex maternal and paternal hypomethylation and a common source of haematopoietic stem cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Epigenetics in cancer: targeting chromatin modifications

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

DNA methylation profiles in monozygotic and dizygotic twins.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Heritability in the genomics era — concepts and misconceptions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Phenotypically concordant and discordant monozygotic twins display different DNA copy-number-variation profiles

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Epigenetics of personality traits: an illustrative study of identical twins discordant for risk-taking behavior

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Increased DNA methylation at the AXIN1 gene in a monozygotic twin from a pair discordant for a caudal duplication anomaly

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Adult consequences of fetal growth restriction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Epigenetic differences arise during the lifetime of monozygotic twins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

The effect of moderate alcohol consumption on bone mineral density: a study of female twins.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

The history of cancer epigenetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Imprinting errors and developmental asymmetry

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Lifestyle differences in twin pairs discordant for basal cell carcinoma of the skin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Classical twin studies and beyond

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Genetic and environmental causes of variation in basal levels of blood cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

The language of covalent histone modifications

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Sporadic imprinting defects in Prader-Willi syndrome and Angelman syndrome: implications for imprint-switch models, genetic counseling, and prenatal diagnosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

MeCP2 is a transcriptional repressor with abundant binding sites in genomic chromatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Some causes of genotypic and phenotypic discordance in monozygotic twin pairs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Human CENP-A contains a histone H3 related histone fold domain that is required for targeting to the centromere

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

7 July 2018

Epigenetics: an overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Hypomethylation distinguishes genes of some human cancers from their normal counterparts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

CpG methylation of the cAMP-responsive enhancer/promoter sequence TGACGTCA abolishes specific factor binding as well as transcriptional activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

X inactivation, differentiation, and DNA methylation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4254430

A study of diabetes mellitus within a large sample of Australian twins

7 July 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

Evidence that BMI and type 2 diabetes share only a minor fraction of genetic variance: a follow-up study of 23,585 monozygotic and dizygotic twins from the Finnish Twin Cohort Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

The genetic heterogeneity of "schizophrenia".

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

Monozygotic female twins discordant for Silver-Russell syndrome and hypomethylation of the H19-DMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

Psoriasis in Norwegian twins: contribution of genetic and environmental effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

Genetic susceptibility of myocardial infarction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

Leisure activity, health, and medical correlates of neurocognitive performance among monozygotic twins: the Older Australian Twins Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

Leisure-time physical activity and artery lumen diameters: A monozygotic co-twin control study

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

Monozygotic twins exhibit numerous epigenetic differences: clues to twin discordance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

Domains of genome-wide gene expression dysregulation in Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

CRISPRs and epigenome editing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

Epigenome-wide association studies without the need for cell-type composition

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

Genetic and environmental causes of variation in basal levels of blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2FS13073-014-0060-Z

DNA modification mechanisms and gene activity during development

21 January 2018

1 reference

12 December 2020

Genomic and epigenomic analyses of monozygotic twins discordant for congenital renal agenesis

1 reference

12 December 2020

Silver-Russell patients showing a broad range of ICR1 and ICR2 hypomethylation in different tissues

1 reference

12 December 2020

Discordant KCNQ1OT1 imprinting in sets of monozygotic twins discordant for Beckwith-Wiedemann syndrome

1 reference

12 December 2020

Parental legacy determines methylation and expression of an autosomal transgene: a molecular mechanism for parental imprinting

1 reference

12 December 2020

DNA methylation inhibits transcription indirectly via a methyl-CpG binding protein

1 reference

12 December 2020

Processive methylation of hemimethylated CpG sites by mouse Dnmt1 DNA methyltransferase

1 reference

12 December 2020

10.1186/S13073-014-0060-Z

Identifiers

DOI

1 reference

PubMed ID

25484923

Dimensions Publication ID

3 August 2017

0 references

1 reference

3 August 2017

1 reference

PubMed ID

25484923