Epigenetics and the environment: emerging patterns and implications (Q37972995)

26 August 2017

Epigenetics and the environment: emerging patterns and implications (English)

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26 August 2017

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1

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26 August 2017

Mario F Fraga

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PubMed ID

22215131

26 August 2017

language of work or name

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1 February 2011

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26 August 2017

Nature Reviews Genetics

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26 August 2017

13

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26 August 2017

2

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26 August 2017

97-109

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https://scigraph.springernature.com/pub.10.1038/nrg3142

26 August 2017

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cites work

Histone modification: cause or cog?

1 reference

Establishing, maintaining and modifying DNA methylation patterns in plants and animals

21 January 2018

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Epigenetic transitions in germ cell development and meiosis

21 January 2018

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DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

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Stability and flexibility of epigenetic gene regulation in mammalian development

21 January 2018

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Intra-individual change over time in DNA methylation with familial clustering

21 January 2018

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Genetic and epigenetic regulation of aging

21 January 2018

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Epigenetic differences arise during the lifetime of monozygotic twins

21 January 2018

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A longitudinal study of epigenetic variation in twins

21 January 2018

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Targets and dynamics of promoter DNA methylation during early mouse development.

21 January 2018

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Charting histone modifications and the functional organization of mammalian genomes

21 January 2018

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Non-coding RNAs as regulators of embryogenesis

21 January 2018

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An siRNA pathway prevents transgenerational retrotransposition in plants subjected to stress.

21 January 2018

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Epigenetic contribution to stress adaptation in plants

21 January 2018

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Environmental epigenomics and disease susceptibility

21 January 2018

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Decoding the epigenetic language of neuronal plasticity

21 January 2018

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Socioeconomic status and the brain: mechanistic insights from human and animal research

21 January 2018

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Genomics of environmentally induced phenotypes in 2 extremely plastic arthropods.

21 January 2018

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Nutritional control of reproductive status in honeybees via DNA methylation

21 January 2018

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The honey bee epigenomes: differential methylation of brain DNA in queens and workers

21 January 2018

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Genomic imprinting in the mealybugs

21 January 2018

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Sciara as an experimental model for studies on the evolutionary relationships between the zygotic, maternal and environmental primary signals for sexual development.

21 January 2018

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Weird animal genomes and the evolution of vertebrate sex and sex chromosomes

21 January 2018

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Epigenetic regulation of stress responses in plants

21 January 2018

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Vernalization: winter and the timing of flowering in plants

21 January 2018

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An epigenetic mutation responsible for natural variation in floral symmetry

21 January 2018

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Epigenetic differentiation and relationship to adaptive genetic divergence in discrete populations of the violet Viola cazorlensis.

21 January 2018

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Stable epigenetic effects impact adaptation in allopolyploid orchids (Dactylorhiza: Orchidaceae)

21 January 2018

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Epigenetic variation in mangrove plants occurring in contrasting natural environment

21 January 2018

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A transposon-induced epigenetic change leads to sex determination in melon

21 January 2018

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Stress-induced DNA methylation changes and their heritability in asexual dandelions.

21 January 2018

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Selected aspects of transgenerational epigenetic inheritance and resetting in plants

21 January 2018

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Animal models to study environmental epigenetics

21 January 2018

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Transgenerational epigenetic inheritance: more questions than answers.

21 January 2018

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Epigenetic mechanisms that underpin metabolic and cardiovascular diseases

21 January 2018

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Persistent epigenetic differences associated with prenatal exposure to famine in humans

21 January 2018

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DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

21 January 2018

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Season of conception in rural gambia affects DNA methylation at putative human metastable epialleles

21 January 2018

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Genomic imprinting: the emergence of an epigenetic paradigm.

21 January 2018

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Genomic imprinting and human disease

21 January 2018

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Transposable elements: targets for early nutritional effects on epigenetic gene regulation

21 January 2018

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Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets.

21 January 2018

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Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome

21 January 2018

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Sex- and diet-specific changes of imprinted gene expression and DNA methylation in mouse placenta under a high-fat diet

21 January 2018

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DNA methylation, insulin resistance, and blood pressure in offspring determined by maternal periconceptional B vitamin and methionine status

21 January 2018

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Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals

21 January 2018

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The thrifty phenotype hypothesis

21 January 2018

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Methylation variation at IGF2 differentially methylated regions and maternal folic acid use before and during pregnancy

21 January 2018

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Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child

21 January 2018

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Rapid DNA methylation changes after exposure to traffic particles

21 January 2018

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Changes in DNA Methylation Patterns in Subjects Exposed to Low-Dose Benzene

21 January 2018

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Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context

21 January 2018

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The influence of aging, environmental exposures and local sequence features on the variation of DNA methylation in blood

21 January 2018

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Tobacco-smoking-related differential DNA methylation: 27K discovery and replication

21 January 2018

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Epigenetic regulation of repetitive elements is attenuated by prolonged heat stress in Arabidopsis.

21 January 2018

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Chromatin remodeling in plant cell culture: patterns of DNA methylation and histone H3 and H4 acetylation vary during growth of asynchronous potato cell suspensions

21 January 2018

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DNA methylation reprogramming during plant sexual reproduction?

21 January 2018

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Repeat elements and the Arabidopsis DNA methylation landscape

21 January 2018

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Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location

21 January 2018

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Assessing the impact of transgenerational epigenetic variation on complex traits

21 January 2018

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Natural epigenetic variation in plant species: a view from the field

21 January 2018

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A naturally occurring epigenetic mutation in a gene encoding an SBP-box transcription factor inhibits tomato fruit ripening.

21 January 2018

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Heritable epigenetic mutation of a transposon-flanked Arabidopsis gene due to lack of the chromatin-remodeling factor DDM1.

21 January 2018

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A role for RNAi in the selective correction of DNA methylation defects.

21 January 2018

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Epigenetic events in mammalian germ-cell development: reprogramming and beyond

21 January 2018

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Transgenerational epigenetic instability is a source of novel methylation variants

21 January 2018

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Zygotic resetting of the HISTONE 3 variant repertoire participates in epigenetic reprogramming in Arabidopsis.

21 January 2018

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Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse.

21 January 2018

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Epigenetic inheritance at the agouti locus in the mouse

21 January 2018

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Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice

21 January 2018

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Epigenetic transgenerational actions of endocrine disruptors and male fertility

21 January 2018

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Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm

21 January 2018

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Epigenetic transgenerational actions of vinclozolin on promoter regions of the sperm epigenome

21 January 2018

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Specific transgenerational imprinting effects of the endocrine disruptor methoxychlor on male gametes

21 January 2018

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Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa

21 January 2018

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Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans

21 January 2018

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H2A.Z-containing nucleosomes mediate the thermosensory response in Arabidopsis.

21 January 2018

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A PHD-polycomb repressive complex 2 triggers the epigenetic silencing of FLC during vernalization

21 January 2018

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Cold-induced silencing by long antisense transcripts of an Arabidopsis Polycomb target

21 January 2018

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Inheritance of stress-induced, ATF-2-dependent epigenetic change

21 January 2018

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The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis.

21 January 2018

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Paramutation's properties and puzzles

21 January 2018

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RNAi-independent heterochromatin nucleation by the stress-activated ATF/CREB family proteins

21 January 2018

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Maternal ethanol consumption alters the epigenotype and the phenotype of offspring in a mouse model

21 January 2018

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Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome

21 January 2018

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Maternal nutrient supplementation counteracts bisphenol A-induced DNA hypomethylation in early development

21 January 2018

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An expression microarray approach for the identification of metastable epialleles in the mouse genome

21 January 2018

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Dietary histone deacetylase inhibitors: from cells to mice to man

21 January 2018

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Requirement of RIZ1 for cancer prevention by methyl-balanced diet

21 January 2018

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

21 January 2018

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Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

21 January 2018

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SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities

21 January 2018

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Calorie restriction and the exercise of chromatin

21 January 2018

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Stabilization of Suv39H1 by SirT1 is part of oxidative stress response and ensures genome protection

21 January 2018

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Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 January 2018

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Resveratrol is not a direct activator of SIRT1 enzyme activity

21 January 2018

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Substrate-specific activation of sirtuins by resveratrol

21 January 2018

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Gender specific differences in levels of DNA methylation at selected loci from human total blood: a tendency toward higher methylation levels in males.

21 January 2018

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Growth hormone regulation of sex-dependent liver gene expression

21 January 2018

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DNA methylation profiles in monozygotic and dizygotic twins.

21 January 2018

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DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome.

21 January 2018

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Analysis of DNA methylation in a three-generation family reveals widespread genetic influence on epigenetic regulation.

21 January 2018

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Extensive sequence-influenced DNA methylation polymorphism in the human genome

21 January 2018

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An association between variants in the IGF2 gene and Beckwith-Wiedemann syndrome: interaction between genotype and epigenotype.

21 January 2018

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Allele-specific DNA methylation in mouse strains is mainly determined by cis-acting sequences

21 January 2018

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Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

21 January 2018

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Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer.

21 January 2018

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Epigenetic reprogramming in plant and animal development

21 January 2018

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Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality

21 January 2018

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Domain-specific response of imprinted genes to reduced DNMT1.

21 January 2018

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The prevalence of folate-remedial MTHFR enzyme variants in humans

21 January 2018

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Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis

21 January 2018

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Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus

21 January 2018

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Spatial, temporal and interindividual epigenetic variation of functionally important DNA methylation patterns.

21 January 2018

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Too late for the midwife toad: stress, variability and Hsp90.

21 January 2018

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ChIP-seq: advantages and challenges of a maturing technology

21 January 2018

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Computation for ChIP-seq and RNA-seq studies

21 January 2018

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A decade of exploring the cancer epigenome - biological and translational implications

21 January 2018

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Phenotypic instability and epigenetic variability in a diploid potato of hybrid origin, Solanum ruiz-lealii

21 January 2018

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Obesity in young men after famine exposure in utero and early infancy

21 January 2018

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Association of the INS VNTR with size at birth. ALSPAC Study Team. Avon Longitudinal Study of Pregnancy and Childhood

21 January 2018

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Neonatal thyroid function in Seveso 25 years after maternal exposure to dioxin

21 January 2018

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Relation of serial changes in childhood body-mass index to impaired glucose tolerance in young adulthood

21 January 2018

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Vernalization in Arabidopsis thaliana is mediated by the PHD finger protein VIN3.

21 January 2018

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Differential expression of a new dominant agouti allele (Aiapy) is correlated with methylation state and is influenced by parental lineage

21 January 2018

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Tobacco smoke induces polycomb-mediated repression of Dickkopf-1 in lung cancer cells

21 January 2018

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Neonatal exposure to diethylstilbestrol alters expression of DNA methyltransferases and methylation of genomic DNA in the mouse uterus

21 January 2018

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The orphan nuclear receptor small heterodimer partner mediates male infertility induced by diethylstilbestrol in mice

21 January 2018

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The role of epigenetics in aging and age-related diseases

21 January 2018

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Epigenetics and environmental chemicals

21 January 2018

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Aberrant promoter hypermethylation in serum DNA from patients with silicosis

21 January 2018

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Culture of preimplantation mouse embryos affects fetal development and the expression of imprinted genes

21 January 2018

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Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring

31 March 2020

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A promoter DNA demethylation landscape of human hematopoietic differentiation

31 March 2020

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Differential effects of culture on imprinted H19 expression in the preimplantation mouse embryo

31 March 2020

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Epigenetic change in IGF2R is associated with fetal overgrowth after sheep embryo culture

31 March 2020

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Distinctive chromatin in human sperm packages genes for embryo development

31 March 2020

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Epigenetic modulation and cancer: effect of metabolic syndrome?

31 March 2020

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Genomic surveys by methylation-sensitive SNP analysis identify sequence-dependent allele-specific DNA methylation

31 March 2020

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Heritable rather than age-related environmental and stochastic factors dominate variation in DNA methylation of the human IGF2/H19 locus

31 March 2020

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Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals

31 March 2020

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Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice.

31 March 2020

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12 December 2020

Obesity, diabetes, and neoplasia in yellow A(vy)/- mice: ectopic expression of the agouti gene

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12 December 2020

Metastable epialleles in mammals

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12 December 2020

Altered imprinted gene methylation and expression in completely ES cell-derived mouse fetuses: association with aberrant phenotypes.

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12 December 2020

Aberrant promoter methylation in bronchial epithelium and sputum from current and former smokers.

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12 December 2020

Identifiers

DOI

10.1038/NRG3142

1 reference

26 August 2017

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PubMed ID

22215131