Experimental treatments for human transmissible spongiform encephalopathies: is there a role for pentosan polysulfate? (Q34625274)

3 August 2017

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title

Experimental treatments for human transmissible spongiform encephalopathies: is there a role for pentosan polysulfate? (English)

1 reference

3 August 2017

Rainov NG

1

1 reference

3 August 2017

Tsuboi Y

2

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3 August 2017

Krolak-Salmon P

3

1 reference

3 August 2017

Vighetto A

4

1 reference

3 August 2017

Doh-Ura K

5

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3 August 2017

language of work or name

English

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publication date

1 May 2007

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Expert Opinion on Biological Therapy

3 August 2017

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3 August 2017

7

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3 August 2017

5

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3 August 2017

713-726

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Biology and genetics of prion diseases

3 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Normal host prion protein necessary for scrapie-induced neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

The molecular biology of prion propagation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Prion protein conversions: insight into mechanisms, TSE transmission barriers and strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Scrapie prions: a three-dimensional model of an infectious fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

RNA molecules stimulate prion protein conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Prion protein peptide neurotoxicity can be mediated by astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Creutzfeldt-Jakob disease: clinical features, epidemiology and tests

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Fatal familial insomnia and familial Creutzfeldt-Jakob disease: clinical, pathological and molecular features.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Iatrogenic Creutzfeldt-Jakob disease at the millennium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Iatrogenic Creutzfeldt-Jakob disease: the waning of an era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Fatal familial insomnia, a prion disease with a mutation at codon 178 of the prion protein gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

A new variant of Creutzfeldt-Jakob disease in the UK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

First hundred cases of variant Creutzfeldt-Jakob disease: retrospective case note review of early psychiatric and neurological features

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Molecular and clinical classification of human prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Novel approaches in diagnosis and therapy of Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Inhibition of prion-protein conversion: a therapeutic tool?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Promising developments bringing prion diseases closer to therapy and prophylaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

A systematic review of prion therapeutics in experimental models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Enhanced antiscrapie effect using combination drug treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

MS-8209, a water-soluble amphotericin B derivative, affects both scrapie agent replication and PrPres accumulation in Syrian hamster scrapie.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Potent inhibition of scrapie-associated PrP accumulation by congo red

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

The anti-prion activity of Congo red. Putative mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Effectiveness of anthracycline against experimental prion disease in Syrian hamsters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Porphyrin and phthalocyanine antiscrapie compounds.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Flupirtine partially prevents neuronal injury induced by prion protein fragment and lead acetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Quinacrine acts as an antioxidant and reduces the toxicity of the prion peptide PrP106-126.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Evaluation of quinacrine treatment for prion diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Creutzfeldt-Jakob disease acquired via a dural graft: failure of therapy with quinacrine and chlorpromazine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Compassionate use of quinacrine in Creutzfeldt-Jakob disease fails to show significant effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Results of quinacrine administration to patients with Creutzfeldt-Jakob disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Chemoprophylaxis of scrapie in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Sulphated glycosaminoglycans prevent the neurotoxicity of a human prion protein fragment

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Prolongation of scrapie incubation period by an injection of dextran sulphate 500 within the month before or after infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Sulphate polyanions prolong the incubation period of scrapie-infected hamsters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Absorption of heparin, LMW heparin and SP54 after subcutaneous injection, assessed by competitive binding assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Pentosan polysulfate sodium for therapy of interstitial cystitis. A double-blind placebo-controlled clinical study

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Pentosan polysulfate-induced thrombocytopenia and thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Distribution of radioiodinated recombinant human nerve growth factor in primate brain following intracerebroventricular infusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Mechanisms of disease: the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Modulation of the blood-brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Cerebrospinal fluid dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Cerebroventricular infusion of pentosan polysulphate in human variant Creutzfeldt-Jakob disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Unsuccessful intraventricular pentosan polysulphate treatment of variant Creutzfeldt-Jakob disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

Quinacrine does not prolong survival in a murine Creutzfeldt-Jakob disease model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

CSF-Brain permeability in the immature sheep fetus: A CSF-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.7.5.713

21 January 2018

Identifiers

DOI

10.1517/14712598.7.5.713

1 reference

3 August 2017

1 reference