Reexamining the polyadenylation signal: were we wrong about AAUAAA? (Q34628809)

3 August 2017

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title

Reexamining the polyadenylation signal: were we wrong about AAUAAA? (English)

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3 August 2017

Clinton C MacDonald

1

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PubMed ID

11997173

3 August 2017

José-Luis Redondo

series ordinal

2

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PubMed ID

11997173

3 August 2017

language of work or name

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1 April 2002

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Molecular and Cellular Endocrinology

3 August 2017

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3 August 2017

190

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3 August 2017

1-2

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3 August 2017

1-8

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Complementary DNA sequencing: expressed sequence tags and human genome project

3 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

DSEF-1 is a member of the hnRNP H family of RNA-binding proteins and stimulates pre-mRNA cleavage and polyadenylation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Identification of alternate polyadenylation sites and analysis of their tissue distribution using EST data.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Patterns of variant polyadenylation signal usage in human genes

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Are U4 small nuclear ribonucleoproteins involved in polyadenylation?

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

RNA ligands selected by cleavage stimulation factor contain distinct sequence motifs that function as downstream elements in 3'-end processing of pre-mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Cleavage site determinants in the mammalian polyadenylation signal

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Elevated levels of the polyadenylation factor CstF 64 enhance formation of the 1kB Testis brain RNA-binding protein (TB-RBP) mRNA in male germ cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Mechanism and regulation of mRNA polyadenylation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

The gene for a variant form of the polyadenylation protein CstF-64 is on chromosome 19 and is expressed in pachytene spermatocytes in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Analysis of the 5'-AAUAAA motif and its flanking sequence in human RNA: relevance to cDNA library sorting

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Regulation of poly(A) site use during mouse B-cell development involves a change in the binding of a general polyadenylation factor in a B-cell stage-specific manner

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Alternative poly(A) site selection in complex transcription units: means to an end?

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

The sequence 5'-AAUAAA-3'forms parts of the recognition site for polyadenylation of late SV40 mRNAs.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Mammalian polyadenylation sites: implications for differential display.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Alternate polyadenylation in human mRNAs: a large-scale analysis by EST clustering.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

In silico detection of control signals: mRNA 3'-end-processing sequences in diverse species

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

U1 snRNP inhibits pre-mRNA polyadenylation through a direct interaction between U1 70K and poly(A) polymerase.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Alpha-thalassaemia caused by a polyadenylation signal mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Initial sequencing and analysis of the human genome

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https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Cloning of cDNAs encoding the 160 kDa subunit of the bovine cleavage and polyadenylation specificity factor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Gene structure prediction and alternative splicing analysis using genomically aligned ESTs

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

BodyMap: a collection of 3' ESTs for analysis of human gene expression information.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

No end yet to messenger RNA 3' processing!

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

A possible meiotic function of the peculiar patterns of gene expression in mammalian spermatogenic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Gene index analysis of the human genome estimates approximately 120,000 genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Regulation of alternative polyadenylation by U1 snRNPs and SRp20.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Direct interaction of the U1 snRNP-A protein with the upstream efficiency element of the SV40 late polyadenylation signal

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Accurate and specific polyadenylation of mRNA precursors in a soluble whole-cell lysate

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

A complex protein assembly catalyzes polyadenylation of mRNA precursors

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Alternative poly(A) site utilization during adenovirus infection coincides with a decrease in the activity of a poly(A) site processing factor

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Increase in the 64-kDa subunit of the polyadenylation/cleavage stimulatory factor during the G0 to S phase transition

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Regulation of herpes simplex virus poly (A) site usage and the action of immediate-early protein IE63 in the early-late switch.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

The consensus sequence YGTGTTYY located downstream from the AATAAA signal is required for efficient formation of mRNA 3' termini

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Molecular characterization of the testis specific c-abl mRNA in mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Site-specific polyadenylation in a cell-free reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Accurate cleavage and polyadenylation of exogenous RNA substrate

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3' end formation by two distinct mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

TGTG, G clustering and other signals near non-mammalian vertebrate mRNA 3' termini: some implications.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Nucleotide sequence of testis-derived c-abl cDNAs: implications for testis-specific transcription and abl oncogene activation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Subunits of cyclic adenosine 3',5'-monophosphate-dependent protein kinase show differential and distinct expression patterns during germ cell differentiation: alternative polyadenylation in germ cells gives rise to unique smaller-sized mRNA species.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Heterogeneity in polyadenylation cleavage sites in mammalian mRNA sequences: implications for SAGE analysis.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

UTRdb and UTRsite: specialized databases of sequences and functional elements of 5' and 3' untranslated regions of eukaryotic mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

3' non-coding region sequences in eukaryotic messenger RNA

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

A Gene Map of the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Point mutations in AAUAAA and the poly (A) addition site: effects on the accuracy and efficiency of cleavage and polyadenylation in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Detection of polyadenylation signals in human DNA sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Levels of polyadenylation factor CstF-64 control IgM heavy chain mRNA accumulation and other events associated with B cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Complex protein interactions within the human polyadenylation machinery identify a novel component

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Expressing the human genome

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https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

The roles of RNA-binding proteins in spermatogenesis and male infertility.

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

hnRNP F influences binding of a 64-kilodalton subunit of cleavage stimulation factor to mRNA precursors in mouse B cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

3'-end cleavage and polyadenylation of mRNA precursors

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Two distinct forms of the 64,000 Mr protein of the cleavage stimulation factor are expressed in mouse male germ cells

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Poly(A) site efficiency reflects the stability of complex formation involving the downstream element

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Role of the Conserved AAUAAA Sequence: Four AAUAAA Point Mutants Prevent Messenger RNA 3′ End Formation

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

Functional analysis of point mutations in the AAUAAA motif of the SV40 late polyadenylation signal

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

A multicomponent complex is required for the AAUAAA-dependent cross-linking of a 64-kilodalton protein to polyadenylation substrates

1 reference

https://api.crossref.org/works/10.1016%2FS0303-7207%2802%2900044-8

7 January 2021

10.1016/S0303-7207(02)00044-8

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

11997173