Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration (Q34629538)

3 August 2017

Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration (English)

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3 August 2017

Giuseppe Orsomando

7

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Caterina Bendotti

object named as

Caterina Bendotti

9

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author name string

Laura Conforti

1

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3 August 2017

Lucie Janeckova

2

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3 August 2017

Diana Wagner

3

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3 August 2017

Francesca Mazzola

4

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3 August 2017

Lucia Cialabrini

5

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3 August 2017

Michele Di Stefano

6

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3 August 2017

Giulio Magni

8

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3 August 2017

Neil Smyth

10

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3 August 2017

Michael Coleman

11

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3 August 2017

language of work or name

English

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publication date

14 June 2011

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3 August 2017

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3 August 2017

278

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3 August 2017

2666-2679

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3 August 2017

15

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Structure and function of nicotinamide mononucleotide adenylyltransferase.

3 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Identification and characterization of a second NMN adenylyltransferase gene in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Characterization of human brain nicotinamide 5′-mononucleotide adenylyltransferase-2 and expression in human pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Emerging roles of NAD+ and its metabolites in cell signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Non-nuclear Wld(S) determines its neuroprotective efficacy for axons and synapses in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Calorie restriction--the SIR2 connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Circadian clock feedback cycle through NAMPT-mediated NAD+ biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Enzymes in the NAD+ salvage pathway regulate SIRT1 activity at target gene promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Inhibitors of poly(ADP-ribose) polymerase-1 suppress transcriptional activation in lymphocytes and ameliorate autoimmune encephalomyelitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Regulation of poly(ADP-ribose) polymerase 1 activity by the phosphorylation state of the nuclear NAD biosynthetic enzyme NMN adenylyl transferase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Nicotinamide prevents NAD+ depletion and protects neurons against excitotoxicity and cerebral ischemia: NAD+ consumption by SIRT1 may endanger energetically compromised neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Axonal and cell body protection by nicotinamide adenine dinucleotide in tumor necrosis factor-induced optic neuropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Targeting NMNAT1 to axons and synapses transforms its neuroprotective potency in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Axonal degeneration is blocked by nicotinamide mononucleotide adenylyltransferase (Nmnat) protein transduction into transected axons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Wallerian degeneration, wld(s), and nmnat

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Wld S requires Nmnat1 enzymatic activity and N16-VCP interactions to suppress Wallerian degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Wld S protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

NAD(+) and axon degeneration revisited: Nmnat1 cannot substitute for Wld(S) to delay Wallerian degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Evolutionary divergence of valosin-containing protein/cell division cycle protein 48 binding interactions among endoplasmic reticulum-associated degradation proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte-expressed protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Human homologue of a gene mutated in the slow Wallerian degeneration (C57BL/Wld(s)) mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Unique expression pattern of human nicotinamide mononucleotide adenylyltransferase isozymes in red blood cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Quantitative and qualitative analysis of Wallerian degeneration using restricted axonal labelling in YFP-H mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

The progressive nature of Wallerian degeneration in wild-type and slow Wallerian degeneration (WldS) nerves

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Metabolism control by the circadian clock and vice versa

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Circadian control of the NAD+ salvage pathway by CLOCK-SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Cell biology. PARP-1--a perpetrator of apoptotic cell death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Drosophila NMNAT maintains neural integrity independent of its NAD synthesis activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Transgenic mice expressing the Nmnat1 protein manifest robust delay in axonal degeneration in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Characterization of NAD uptake in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Nicotinamide mononucleotide adenylyl transferase-mediated axonal protection requires enzymatic activity but not increased levels of neuronal nicotinamide adenine dinucleotide

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

Assay Methods for Nicotinamide Mononucleotide Adenylyltransferase of Wide Applicability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08193.X

10.1111/J.1742-4658.2011.08193.X

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference