mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway. (Q34633374)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21342491%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway (English)

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23 January 2020

3

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23 January 2020

author name string

Hwei-Hsien Chen

series ordinal

1

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23 January 2020

Pei-Fei Liao

series ordinal

2

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23 January 2020

publication date

22 February 2011

1 reference

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Journal of Biomedical Science

23 January 2020

published in

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23 January 2020

volume

18

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23 January 2020

page(s)

19

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Positive allosteric modulation of metabotropic glutamate 5 (mGlu5) receptors reverses N-Methyl-D-aspartate antagonist-induced alteration of neuronal firing in prefrontal cortex

23 January 2020

cites work

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A novel selective allosteric modulator potentiates the activity of native metabotropic glutamate receptor subtype 5 in rat forebrain

7 July 2018

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Interactions between ionotropic and metabotropic glutamate receptors regulate cAMP response element-binding protein phosphorylation in cultured striatal neurons

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7 July 2018

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7 July 2018

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Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.

7 July 2018

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Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus.

7 July 2018

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Pharmacological agents acting at subtypes of metabotropic glutamate receptors

7 July 2018

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Selective abolition of the NMDA component of long-term potentiation in mice lacking mGluR5.

7 July 2018

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Mechanisms involved in the metabotropic glutamate receptor-enhancement of NMDA-mediated motoneurone responses in frog spinal cord

7 July 2018

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Pharmacology and functions of metabotropic glutamate receptors

7 July 2018

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7 July 2018

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Group I metabotropic glutamate receptor-mediated calcium signalling and immediate early gene expression in cultured rat striatal neurons

7 July 2018

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NMDA-induced phosphorylation and regulation of mGluR5.

21 January 2018

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The mGluR5 antagonist MPEP, but not the mGluR2/3 agonist LY314582, augments PCP effects on prepulse inhibition and locomotor activity

21 January 2018

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mGluR5, but not mGluR1, antagonist modifies MK-801-induced locomotor activity and deficit of prepulse inhibition.

21 January 2018

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The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates PCP-induced cognitive deficits in rats

21 January 2018

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Ketamine, but not propofol, anaesthesia is regulated by metabotropic glutamate 5 receptors.

21 January 2018

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Attenuation of ketamine-evoked behavioral responses by mGluR5 positive modulators in mice.

21 January 2018

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Adenosine A2A receptors and metabotropic glutamate 5 receptors are co-localized and functionally interact in the hippocampus: a possible key mechanism in the modulation of N-methyl-D-aspartate effects

21 January 2018

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Group I metabotropic glutamate receptors modulate glutamate and gamma-aminobutyric acid release in the periaqueductal grey of rats

21 January 2018

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Bursting of prefrontal cortex neurons in awake rats is regulated by metabotropic glutamate 5 (mGlu5) receptors: rate-dependent influence and interaction with NMDA receptors

21 January 2018

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Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release

21 January 2018

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NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin

21 January 2018

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Regulation of phosphorylation of NMDA receptor NR1 subunits in the rat neostriatum by group I metabotropic glutamate receptors in vivo

21 January 2018

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Two distinct signaling pathways upregulate NMDA receptor responses via two distinct metabotropic glutamate receptor subtypes.

21 January 2018

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26 October 2018

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12 December 2020

(RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus

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12 December 2020

Glutamate receptors: brain function and signal transduction

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Potentiation of NMDA and AMPA responses by the specific mGluR5 agonist CHPG in spinal cord motoneurons

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12 December 2020

Identifiers

DOI

10.1186/1423-0127-18-19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21342491%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

23 January 2020

0 references

1 reference

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23 January 2020

PubMed publication ID

21342491

1 reference