Cardiac function is regulated by B56α-mediated targeting of protein phosphatase 2A (PP2A) to contractile relevant substrates. (Q34634141)

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21 February 2020

title

Cardiac function is regulated by B56α-mediated targeting of protein phosphatase 2A (PP2A) to contractile relevant substrates (English)

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21 February 2020

7

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Jan Sebastian Schulte

8

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21 February 2020

author name string

Uwe Kirchhefer

1

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21 February 2020

Christiane Brekle

2

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21 February 2020

John Eskandar

3

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21 February 2020

Gunnar Isensee

4

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21 February 2020

Dana Kučerová

5

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21 February 2020

Frank U Müller

6

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21 February 2020

Matthias D Seidl

9

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21 February 2020

Peter Boknik

10

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21 February 2020

language of work or name

English

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publication date

15 October 2014

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Journal of Biological Chemistry

21 February 2020

published in

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21 February 2020

volume

289

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issue

49

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page(s)

33862-33873

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Control of cytoplasmic and nuclear protein kinase A by phosphodiesterases and phosphatases in cardiac myocytes

21 February 2020

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cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3.

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Proteomics analysis of the cardiac myofilament subproteome reveals dynamic alterations in phosphatase subunit distribution

7 July 2018

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Cell therapy enhances function of remote non-infarcted myocardium

7 July 2018

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Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia.

7 July 2018

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miR-1 overexpression enhances Ca(2+) release and promotes cardiac arrhythmogenesis by targeting PP2A regulatory subunit B56alpha and causing CaMKII-dependent hyperphosphorylation of RyR2

7 July 2018

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Cardiac myofilament regulation by protein phosphatase type 1alpha and CapZ

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Protein kinase C zeta. A novel regulator of both phosphorylation and de-phosphorylation of cardiac sarcomeric proteins

7 July 2018

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Molecular basis for PP2A regulatory subunit B56alpha targeting in cardiomyocytes

7 July 2018

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Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56delta subunit

7 July 2018

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Dephosphorylation specificities of protein phosphatase for cardiac troponin I, troponin T, and sites within troponin T.

7 July 2018

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Binding of protein phosphatase 2A to the L-type calcium channel Cav1.2 next to Ser1928, its main PKA site, is critical for Ser1928 dephosphorylation

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Overexpression of the catalytic subunit of protein phosphatase 2A impairs cardiac function

7 July 2018

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Connexin 43 downregulation and dephosphorylation in nonischemic heart failure is associated with enhanced colocalized protein phosphatase type 2A.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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12 December 2020

Role of protein phosphatases in regulation of cardiac inotropy and relaxation

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Identifiers

DOI

10.1074/JBC.M114.598938

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25320082%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

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21 February 2020

1 reference