The ω-3 epoxide of eicosapentaenoic acid inhibits endothelial cell proliferation by p38 MAP kinase activation and cyclin D1/CDK4 down-regulation (Q34636267)

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English	The ω-3 epoxide of eicosapentaenoic acid inhibits endothelial cell proliferation by p38 MAP kinase activation and cyclin D1/CDK4 down-regulation	scientific article

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scholarly article

1 reference

Europe PubMed Central

3 August 2017

The ω-3 epoxide of eicosapentaenoic acid inhibits endothelial cell proliferation by p38 MAP kinase activation and cyclin D1/CDK4 down-regulation (English)

1 reference

Europe PubMed Central

3 August 2017

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author name string

Pei H Cui

1

1 reference

Europe PubMed Central

3 August 2017

Nenad Petrovic

2

1 reference

Europe PubMed Central

3 August 2017

Michael Murray

3

1 reference

Europe PubMed Central

3 August 2017

language of work or name

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publication date

1 March 2011

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Europe PubMed Central

3 August 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

3 August 2017

162

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Europe PubMed Central

3 August 2017

5

1 reference

Europe PubMed Central

3 August 2017

1143-1155

1 reference

Europe PubMed Central

3 August 2017

How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Cytochrome P-450 epoxygenases protect endothelial cells from apoptosis induced by tumor necrosis factor-alpha via MAPK and PI3K/Akt signaling pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Epoxyeicosatrienoic acids, cell signaling and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Constitutive expression of functionally active cyclin-dependent kinases and their binding partners suggests noncanonical functions of cell cycle regulators in differentiated neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Integrin-dependent signal transduction regulating cyclin D1 expression and G1 phase cell cycle progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

14,15-Dihydroxyeicosatrienoic acid activates peroxisome proliferator-activated receptor-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Cytochrome P450 2J2 promotes the neoplastic phenotype of carcinoma cells and is up-regulated in human tumors

1 reference

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7 July 2018

Eicosapentaenoic acid metabolism by cytochrome P450 enzymes of the CYP2C subfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Cell cycle progression without cyclin D-CDK4 and cyclin D-CDK6 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Activation and signaling of the p38 MAP kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Cyclin D1 serves as a cell cycle regulatory switch in actively proliferating cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce angiogenesis via cross-talk with the epidermal growth factor receptor (EGFR).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Polyunsaturated fatty acids (PUFA) and eicosanoids in human health and pathologies

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Resveratrol induces growth inhibition, S-phase arrest, apoptosis, and changes in biomarker expression in several human cancer cell lines.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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7 July 2018

Cytochrome p450 epoxygenase metabolism of arachidonic acid inhibits apoptosis

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7 July 2018

Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27(Kip1) in the cyclin E-cdk2 complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Docosahexaenoic acid, a peroxisome proliferator-activated receptor-alpha ligand, induces apoptosis in vascular smooth muscle cells by stimulation of p38 mitogen-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

n-3 polyunsaturated fatty acids and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Selective activation of p38alpha and p38gamma by hypoxia. Role in regulation of cyclin D1 by hypoxia in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

n-3 and n-6 fatty acid processing and growth effects in neoplastic and non-cancerous human mammary epithelial cell lines.

1 reference

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7 July 2018

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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7 July 2018

Transforming p21ras mutants and c-Ets-2 activate the cyclin D1 promoter through distinguishable regions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3051386

7 July 2018

N-3 fatty acids inhibit vascular calcification via the p38-mitogen-activated protein kinase and peroxisome proliferator-activated receptor-gamma pathways.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01113.X

21 January 2018

Role of EETs in regulation of endothelial permeability in rat lung

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01113.X

21 January 2018

Different mechanisms of saturated versus polyunsaturated FFA-induced apoptosis in human endothelial cells

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https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01113.X

21 January 2018

Epoxyeicosatrienoic acids function as selective, endogenous antagonists of native thromboxane receptors: identification of a novel mechanism of vasodilation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01113.X

21 January 2018

Synthesis and NMR characterization of the methyl esters of eicosapentaenoic acid monoepoxides.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01113.X

21 January 2018

Genetic and epigenetic alterations in lung tumors from bitransgenic Ki-rasG12C expressing mice.

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21 January 2018

Post-transcriptional regulation of cyclin D1 expression during G2 phase

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https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01113.X

21 January 2018

Docosahexaenoic acid inhibits cancer cell growth via p27Kip1, CDK2, ERK1/ERK2, and retinoblastoma phosphorylation.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01113.X

21 January 2018

N-3 and N-6 fatty acids in breast adipose tissue and relative risk of breast cancer in a case-control study in Tours, France.

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https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01113.X

21 January 2018

Phospho-STAT5 accumulation in nuclear fractions from vitamin A-deficient rat liver

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21 January 2018

Cytochrome P450 2C9-induced endothelial cell proliferation involves induction of mitogen-activated protein (MAP) kinase phosphatase-1, inhibition of the c-Jun N-terminal kinase, and up-regulation of cyclin D1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01113.X

21 January 2018

11,12-Epoxyeicosatrienoic acid-induced inhibition of FOXO factors promotes endothelial proliferation by down-regulating p27Kip1.

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https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01113.X

21 January 2018

Modulation of angiogenesis by omega-3 polyunsaturated fatty acids is mediated by cyclooxygenases

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https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01113.X

21 January 2018

Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids

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https://api.crossref.org/works/10.1111%2FJ.1476-5381.2010.01113.X

21 January 2018

Cerebral capillary endothelial cell mitogenesis and morphogenesis induced by astrocytic epoxyeicosatrienoic Acid

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21 January 2018

p38 MAP kinase negatively regulates cyclin D1 expression in airway smooth muscle cells

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26 October 2018

p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation

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12 December 2020

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Expression and amplification of cyclin genes in human breast cancer

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https://pubmed.ncbi.nlm.nih.gov/21077851

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Effects of dietary omega-3 fatty acids on human breast cancer growth and metastases in nude mice

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Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-dihydroxyvitamin D3 in HL60 cells

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https://pubmed.ncbi.nlm.nih.gov/21077851

12 December 2020

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Identifiers

10.1111/J.1476-5381.2010.01113.X

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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