Suicide inactivation of peroxidases and the challenge of engineering more robust enzymes (Q34657810)

3 August 2017

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title

Suicide inactivation of peroxidases and the challenge of engineering more robust enzymes (English)

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3 August 2017

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Brenda Valderrama

1

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3 August 2017

Marcela Ayala

series ordinal

2

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3 August 2017

Rafael Vazquez-Duhalt

series ordinal

3

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3 August 2017

publication date

1 May 2002

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3 August 2017

published in

Chemistry and Biology

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3 August 2017

volume

9

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3 August 2017

issue

5

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3 August 2017

page(s)

555-565

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Mitochondrial production of hydrogen peroxide regulation by nitric oxide and the role of ubisemiquinone

3 August 2017

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Catalase-peroxidase (Mycobacterium tuberculosis KatG) catalysis and isoniazid activation

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7 January 2021

Molecular cloning and sequencing of a non-haem bromoperoxidase gene from Streptomyces aureofaciens ATCC 10762

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7 January 2021

Biocatalytic oxidation of polycyclic aromatic hydrocarbons by hemoglobin and hydrogen peroxide

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Role of manganese peroxidases and lignin peroxidases of Phanerochaete chrysosporium in the decolorization of kraft bleach plant effluent.

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7 January 2021

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7 January 2021

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7 January 2021

Biosensors based on novel plant peroxidases: a comparative study

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7 January 2021

Biotechnological production of prostaglandin

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7 January 2021

Detection of a tryptophan radical in the reaction of ascorbate peroxidase with hydrogen peroxide

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7 January 2021

Horseradish peroxidase Phe172-->Tyr mutant. Sequential formation of compound I with a porphyrin radical cation and a protein radical.

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7 January 2021

Kinetics of the reaction of compound II of horseradish peroxidase with hydrogen peroxide to form compound III.

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7 January 2021

Kinetic study of the inactivation of ascorbate peroxidase by hydrogen peroxide.

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7 January 2021

Inactivation of Coprinus cinereus peroxidase by 4-chloroaniline during turnover: comparison with horseradish peroxidase and bovine lactoperoxidase.

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7 January 2021

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7 January 2021

Catalytic mechanisms and regulation of lignin peroxidase.

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7 January 2021

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7 January 2021

Quantitating direct chlorine transfer from enzyme to substrate in chloroperoxidase-catalyzed reactions

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7 January 2021

Identification of intermediates in the catalytic cycle of chloroperoxidase

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7 January 2021

Utilization of peroxide and its relevance in oxygen insertion reactions catalyzed by chloroperoxidase

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7 January 2021

Improvement of the total turnover number and space-time yield for chloroperoxidase catalyzed oxidation

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7 January 2021

Heme-Containing Oxygenases

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7 January 2021

The catalytic pathway of cytochrome p450cam at atomic resolution

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7 January 2021

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7 January 2021

Identification of the heme-modified peptides from cumene hydroperoxide-inactivated cytochrome P450 3A4.

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7 January 2021

Heme and apoprotein modification of cytochrome P450 2B4 during its oxidative inactivation in monooxygenase reconstituted system

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7 January 2021

Detection of peroxyl and alkoxyl radicals produced by reaction of hydroperoxides with heme-proteins by electron spin resonance spectroscopy

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7 January 2021

Mechanism of radical production from the reaction of cytochrome c with organic hydroperoxides. An ESR spin trapping investigation

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7 January 2021

A cytochrome c variant resistant to heme degradation by hydrogen peroxide

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7 January 2021

Characterization of cytochrome c free radical reactions with peptides by mass spectrometry

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7 January 2021

ESR spin-trapping of a protein-derived tyrosyl radical from the reaction of cytochrome c with hydrogen peroxide

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7 January 2021

Modified cytochrome c/H2O2 system: spectroscopic EPR investigation of the biocatalytic behaviour

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7 January 2021

The Molecular Mechanism of Autoxidation for Myoglobin and Hemoglobin: A Venerable Puzzle

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7 January 2021

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7 January 2021

An EPR study of the peroxyl radicals induced by hydrogen peroxide in the haem proteins

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

A mechanistic study of self-inactivation of the peroxidase activity in prostaglandin H synthase-1

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7 January 2021

A comparative study of the inactivation of wild-type, recombinant and two mutant horseradish peroxidase isoenzymes C by hydrogen peroxide and m-chloroperoxybenzoic acid.

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Reactions of prostaglandin H synthase with monosubstituted hydrazines and diazenes. Formation of iron(II)-diazene and iron(III)-sigma-alkyl or iron(III)-sigma-aryl complexes

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7 January 2021

Coupled oxidation of heme by myoglobin is mediated by exogenous peroxide

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7 January 2021

Stereospecific haem cleavage. A model for the formation of bile-pigment isomers in vivo and in vitro

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7 January 2021

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7 January 2021

Inactivation of peroxidase by hydrogen peroxide and its protection by a reductant agent

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7 January 2021

Kinetics of the formation of p-670 and of the decay of compound III of horseradish peroxidase

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7 January 2021

Oxidation of melatonin and tryptophan by an HRP cycle involving compound III.

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7 January 2021

Electron paramagnetic resonance and electron nuclear double resonance spectroscopic identification and characterization of the tyrosyl radicals in prostaglandin H synthase 1

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7 January 2021

The nature of the intermediates in the reactions of Fe(III)- and Mn(III)-microperoxidase-8 with H(2)O(2): a rapid kinetics study

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7 January 2021

Autocatalytic formation of a hydroxy group at C beta of trp171 in lignin peroxidase

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7 January 2021

Two substrate interaction sites in lignin peroxidase revealed by site-directed mutagenesis

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7 January 2021

The crystal structure of lignin peroxidase at 1.70 A resolution reveals a hydroxy group on the cbeta of tryptophan 171: a novel radical site formed during the redox cycle

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7 January 2021

Heme protein radicals: formation, fate, and biological consequences.

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7 January 2021

Direct detection of a globin-derived radical in leghaemoglobin treated with peroxides

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7 January 2021

The role of redox-active amino acids on compound I stability, substrate oxidation, and protein cross-linking in yeast cytochrome C peroxidase

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7 January 2021

Spin trapping and protein cross-linking of the lactoperoxidase protein radical

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7 January 2021

EPR spin-trapping of a myeloperoxidase protein radical

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7 January 2021

Directed evolution: the 'rational' basis for 'irrational' design.

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7 January 2021

Improved biocatalysts by directed evolution and rational protein design

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7 January 2021

Engineering the active site of ascorbate peroxidase

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7 January 2021

Comparing the effect on protein stability of methionine oxidation versus mutagenesis: steps toward engineering oxidative resistance in proteins

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7 January 2021

Critical role of the residue size at position 87 in H2O2- dependent substrate hydroxylation activity and H2O2 inactivation of cytochrome P450BM-3.

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7 January 2021

Superoxide produced in the heme pocket of the beta-chain of hemoglobin reacts with the beta-93 cysteine to produce a thiyl radical

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7 January 2021

Engineering of the H2O2-binding pocket region of a recombinant manganese peroxidase to be resistant to H2O2.

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7 January 2021

In vitro evolution of horse heart myoglobin to increase peroxidase activity

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7 January 2021

Directed molecular evolution of cytochrome c peroxidase

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7 January 2021

Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation

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7 January 2021

Directed evolution of a fungal peroxidase

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7 January 2021

Peroxidase self-inactivation in prostaglandin H synthase-1 pretreated with cyclooxygenase inhibitors or substituted with mangano protoporphyrin IX.

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7 January 2021

Structure of soybean seed coat peroxidase: A plant peroxidase with unusual stability and haem-apoprotein interactions

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7 January 2021

Arabidopsis ATP A2 peroxidase. Expression and high-resolution structure of a plant peroxidase with implications for lignification

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7 January 2021

Structure of barley grain peroxidase refined at 1.9-A resolution. A plant peroxidase reversibly inactivated at neutral pH

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7 January 2021

Crystal structure of horseradish peroxidase C at 2.15 A resolution

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7 January 2021

The crystal structure of peanut peroxidase

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7 January 2021

Arabidopsis thaliana peroxidase N: structure of a novel neutral peroxidase

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7 January 2021

Preliminary crystallographic analysis of manganese peroxidase from Phanerochaete chrysosporium

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7 January 2021

Crystal structures of cyanide- and triiodide-bound forms of Arthromyces ramosus peroxidase at different pH values. Perturbations of active site residues and their implication in enzyme catalysis

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7 January 2021

A ligand-gated, hinged loop rearrangement opens a channel to a buried artificial protein cavity

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7 January 2021

Crystal structure of recombinant pea cytosolic ascorbate peroxidase

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7 January 2021

The crystal structure of chloroperoxidase: a heme peroxidase--cytochrome P450 functional hybrid

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7 January 2021

Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity

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7 January 2021

Structure of a cytochrome P450-redox partner electron-transfer complex

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7 January 2021

Crystal structure and refinement of cytochrome P450terp at 2.3 A resolution

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7 January 2021

Crystal structure of nitric oxide reductase from denitrifying fungus Fusarium oxysporum

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7 January 2021

Crystal structure of cytochrome P450 14 -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors

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7 January 2021

Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900149-7

7 January 2021

Crystal structures of metyrapone- and phenylimidazole-inhibited complexes of cytochrome P-450cam

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900149-7

7 January 2021

10.1016/S1074-5521(02)00149-7

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DOI

1 reference

3 August 2017

1 reference