Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes (Q34659248)

3 August 2017

title

Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes (English)

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3 August 2017

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8

Heiner Boeing

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3 August 2017

Olga Pivovarova

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Matthias B Schulze

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Matthias B Schulze

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7

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Joachim Spranger

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5

object named as

Joachim Spranger

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Matthias Möhlig

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Andreas F H Pfeiffer

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Eva Fisher

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3 August 2017

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Natalia Rudovich

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Antje Fischer-Rosinsky

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4

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Antje Fischer-Rosinsky

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publication date

7 October 2009

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Journal of Molecular Medicine

3 August 2017

published in

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volume

87

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3 August 2017

issue

11

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3 August 2017

page(s)

1145-1151

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The Finland-United States investigation of non-insulin-dependent diabetes mellitus genetics (FUSION) study. I. An autosomal genome scan for genes that predispose to type 2 diabetes.

3 August 2017

cites work

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12 December 2020

A genome-wide scan for loci linked to plasma levels of glucose and HbA(1c) in a community-based sample of Caucasian pedigrees: The Framingham Offspring Study

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12 December 2020

Association of polymorphisms in the insulin-degrading enzyme gene with type 2 diabetes in the Korean population.

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12 December 2020

A candidate type 2 diabetes polymorphism near the HHEX locus affects acute glucose-stimulated insulin release in European populations: results from the EUGENE2 study

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12 December 2020

Insulin inhibits peroxisomal fatty acid oxidation in isolated rat hepatocytes

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12 December 2020

Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study

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12 December 2020

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

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12 December 2020

Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.

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12 December 2020

Association and haplotype analysis of the insulin-degrading enzyme (IDE) gene, a strong positional and biological candidate for type 2 diabetes susceptibility

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12 December 2020

Insulin-degrading enzyme is differentially expressed and developmentally regulated in various rat tissues

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12 December 2020

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

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12 December 2020

An accurate risk score based on anthropometric, dietary, and lifestyle factors to predict the development of type 2 diabetes

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12 December 2020

Use of the oral glucose tolerance test to assess insulin release and insulin sensitivity.

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12 December 2020

Recruitment procedures of EPIC-Germany. European Investigation into Cancer and Nutrition

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12 December 2020

Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase

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12 December 2020

An insulin-degrading enzyme inhibitor decreases amylin degradation, increases amylin-induced cytotoxicity, and increases amyloid formation in insulinoma cell cultures

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12 December 2020

Analysis of case-cohort designs

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12 December 2020

Insulin-degrading enzyme haplotypes affect insulin levels but not dementia risk.

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12 December 2020

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

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12 December 2020

Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals.

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12 December 2020

Evidence that the gene encoding insulin degrading enzyme influences human lifespan

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12 December 2020

Quantitative trait loci near the insulin-degrading enzyme (IDE) gene contribute to variation in plasma insulin levels

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12 December 2020

A genome-wide association study identifies novel risk loci for type 2 diabetes

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12 December 2020

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

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12 December 2020

Reduced hepatic insulin extraction in response to gastric inhibitory polypeptide compensates for reduced insulin secretion in normal-weight and normal glucose tolerant first-degree relatives of type 2 diabetic patients

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12 December 2020

A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q

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12 December 2020

A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other

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12 December 2020

The influence of genetic variations in HHEX gene on insulin metabolism in the German MESYBEPO cohort

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12 December 2020

Follow-up procedures in EPIC-Germany--data quality aspects. European Prospective Investigation into Cancer and Nutrition

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12 December 2020

Overexpression of insulin degrading enzyme: cellular localization and effects on insulin signaling

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12 December 2020

Variation in the HHEX–IDE gene region predisposes to type 2 diabetes in the prospective, population-based EPIC-Potsdam cohort

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12 December 2020

Insulin degradation: progress and potential

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12 December 2020

Regulation of protein degradation by insulin-degrading enzyme: analysis by small interfering RNA-mediated gene silencing

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12 December 2020

High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people

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12 December 2020

10.1007/S00109-009-0540-6

Identifiers

DOI

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Dimensions Publication ID

3 August 2017

1037381147

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