Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF. (Q34682122)

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English	Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF.	scientific article

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scholarly article

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Europe PubMed Central

3 August 2017

Lipopolysaccharide-mediated interferon regulatory factor activation involves TBK1-IKKepsilon-dependent Lys(63)-linked polyubiquitination and phosphorylation of TANK/I-TRAF. (English)

1 reference

Europe PubMed Central

3 August 2017

lipopolysaccharide

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phosphorylation

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based on heuristic

inferred from title

object named as

Eric Muraille

8

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author name string

Jean-Stéphane Gatot

1

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Europe PubMed Central

3 August 2017

Romain Gioia

2

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Europe PubMed Central

3 August 2017

Tieu-Lan Chau

3

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Europe PubMed Central

3 August 2017

Félicia Patrascu

4

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Europe PubMed Central

3 August 2017

Michael Warnier

5

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Europe PubMed Central

3 August 2017

Pierre Close

6

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Europe PubMed Central

3 August 2017

Jean-Paul Chapelle

7

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Europe PubMed Central

3 August 2017

Keith Brown

9

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Europe PubMed Central

3 August 2017

Ulrich Siebenlist

10

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Europe PubMed Central

3 August 2017

Jacques Piette

11

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Europe PubMed Central

3 August 2017

Emmanuel Dejardin

12

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Europe PubMed Central

3 August 2017

Alain Chariot

13

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Europe PubMed Central

3 August 2017

language of work or name

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publication date

6 September 2007

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Europe PubMed Central

3 August 2017

number of pages

16

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Journal of Biological Chemistry

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Europe PubMed Central

3 August 2017

282

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Europe PubMed Central

3 August 2017

43

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Europe PubMed Central

3 August 2017

31131-31146

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Europe PubMed Central

3 August 2017

Cell type-specific involvement of RIG-I in antiviral response

1 reference

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IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptors

1 reference

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How Toll-like receptors signal: what we know and what we don't know

1 reference

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Type I interferons in host defense

1 reference

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Pathogen recognition and innate immunity

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https://api.crossref.org/works/10.1074%2FJBC.M701690200

21 January 2018

Recognition and signaling by toll-like receptors.

1 reference

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21 January 2018

Essential function for the kinase TAK1 in innate and adaptive immune responses.

1 reference

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21 January 2018

TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

1 reference

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Specificity in Toll-like receptor signalling through distinct effector functions of TRAF3 and TRAF6

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Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

1 reference

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Cutting Edge: NF-kappaB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation

1 reference

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21 January 2018

TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-kappaB activation.

1 reference

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21 January 2018

IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex

1 reference

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NF-kappaB activation through IKK-i-dependent I-TRAF/TANK phosphorylation

1 reference

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21 January 2018

NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

1 reference

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21 January 2018

Tumor necrosis factor receptor associated factor 2 is a mediator of NF-kappa B activation by latent infection membrane protein 1, the Epstein-Barr virus transforming protein

1 reference

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21 January 2018

I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction

1 reference

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21 January 2018

Association of the adaptor TANK with the I kappa B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases

1 reference

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21 January 2018

IKK-i/IKKepsilon controls constitutive, cancer cell-associated NF-kappaB activity via regulation of Ser-536 p65/RelA phosphorylation

1 reference

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Nuclear accumulation of cRel following C-terminal phosphorylation by TBK1/IKK epsilon

1 reference

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

1 reference

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21 January 2018

Triggering the interferon antiviral response through an IKK-related pathway

1 reference

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21 January 2018

The roles of two IkappaB kinase-related kinases in lipopolysaccharide and double stranded RNA signaling and viral infection

1 reference

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21 January 2018

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

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21 January 2018

Signaling to NF-kappaB

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21 January 2018

Ubiquitin signalling in the NF-kappaB pathway

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https://api.crossref.org/works/10.1074%2FJBC.M701690200

21 January 2018

Posttranslational modifications of NEMO and its partners in NF-kappaB signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701690200

21 January 2018

TAK1 is a ubiquitin-dependent kinase of MKK and IKK

1 reference

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21 January 2018

A role for NF-kappaB essential modifier/IkappaB kinase-gamma (NEMO/IKKgamma) ubiquitination in the activation of the IkappaB kinase complex by tumor necrosis factor-alpha

1 reference

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21 January 2018

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-kappaB activation [corrected]

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M701690200

21 January 2018

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

1 reference

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21 January 2018

The Crohn's disease protein, NOD2, requires RIP2 in order to induce ubiquitinylation of a novel site on NEMO

1 reference

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21 January 2018

CIKS, a connection to Ikappa B kinase and stress-activated protein kinase

1 reference

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21 January 2018

Physical and functional interaction of filamin (actin-binding protein-280) and tumor necrosis factor receptor-associated factor 2.

1 reference

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21 January 2018

TNFalpha- and IKKbeta-mediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKKgamma and NF-kappaB activation

1 reference

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Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation

1 reference

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A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference

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SIKE is an IKK epsilon/TBK1-associated suppressor of TLR3- and virus-triggered IRF-3 activation pathways

1 reference

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Involvement of TBK1 and IKKepsilon in lipopolysaccharide-induced activation of the interferon response in primary human macrophages.

1 reference

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Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

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Regulatory functions of ubiquitination in the immune system

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Immunity by ubiquitylation: a reversible process of modification

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Noncanonical MMS2-encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair

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Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

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Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling

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Two pathways to NF-kappaB.

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Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK

1 reference

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The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling

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Site-specific Lys-63-linked tumor necrosis factor receptor-associated factor 6 auto-ubiquitination is a critical determinant of I kappa B kinase activation

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Specificity of TRAF3 in its negative regulation of the noncanonical NF-kappa B pathway

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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

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Identification of proangiogenic genes and pathways by high-throughput functional genomics: TBK1 and the IRF3 pathway

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RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival

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IKK epsilon regulates F actin assembly and interacts with Drosophila IAP1 in cellular morphogenesis

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Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

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Identifiers

10.1074/JBC.M701690200

1 reference

Europe PubMed Central

3 August 2017

1 reference

Europe PubMed Central

3 August 2017

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