Influence of the prion protein gene, Prnp, on scrapie susceptibility in sheep (Q34685443)

3 August 2017

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title

Influence of the prion protein gene, Prnp, on scrapie susceptibility in sheep (English)

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3 August 2017

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Michael A Tranulis

1

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PubMed ID

12064254

3 August 2017

language of work or name

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1 January 2002

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Acta Pathologica et Microbiologica Scandinavica

3 August 2017

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3 August 2017

110

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3 August 2017

1

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3 August 2017

33-43

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Identification of a protein that purifies with the scrapie prion.

3 August 2017

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Novel proteinaceous infectious particles cause scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

A cellular gene encodes scrapie PrP 27-30 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Molecular cloning and complete sequence of prion protein cDNA from mouse brain infected with the scrapie agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Identification of a gene which controls the incubation period of some strains of scrapie agent in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Distinct prion proteins in short and long scrapie incubation period mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Linkage of the gene for the scrapie-associated fibril protein (PrP) to the Sip gene in Cheviot sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Two alleles of a neural protein gene linked to scrapie in sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Complete genomic sequence and analysis of the prion protein gene region from three mammalian species

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Genomic structure of the bovine PrP gene and complete nucleotide sequence of bovine PrP cDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Comparison of expression patterns of PrP mRNA in the developing sheep and mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

PrP (prion) gene expression in sheep may be modulated by alternative polyadenylation of its messenger RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Different scrapie-associated fibril proteins (PrP) are encoded by lines of sheep selected for different alleles of the Sip gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

PrP genotype contributes to determining survival times of sheep with natural scrapie.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Prion protein gene polymorphisms in sheep with natural scrapie and healthy controls in Norway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Genetic susceptibility and transmission factors in scrapie: detailed analysis of an epidemic in a closed flock of Romanov.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Swaledale sheep affected by natural scrapie differ significantly in PrP genotype frequencies from healthy sheep and those selected for reduced incidence of scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

PrP polymorphisms associated with natural scrapie discovered by denaturing gradient gel electrophoresis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Markedly increased susceptibility to natural sheep scrapie of transgenic mice expressing ovine prp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

The signature of scrapie: differences in the PrP genotype profile of scrapie-affected and scrapie-free UK sheep flocks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

PrP genotype and agent effects in scrapie: change in allelic interaction with different isolates of agent in sheep, a natural host of scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Prion protein gene polymorphisms in pedigree sheep in Ireland.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Scrapie susceptibility-linked polymorphisms modulate the in vitro conversion of sheep prion protein to protease-resistant forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Control of scrapie eventually possible?

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Species-barrier-independent prion replication in apparently resistant species

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Efficient transmission of two different sheep scrapie isolates in transgenic mice expressing the ovine PrP gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

A centuries-long epidemic of scrapie in British sheep?

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

First report of polymorphisms in the prion-like protein gene (PRND): implications for human prion diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

The PrP-like protein Doppel gene in sheep and cattle: cDNA sequence and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Genomic organization, comparative analysis, and genetic polymorphisms of the bovine and ovine prion Doppel genes (PRND)

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Frequencies of PrP gene variants in healthy cattle and cattle with BSE in Scotland

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

Identification of multiple quantitative trait loci linked to prion disease incubation period in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

A cellular form of prion protein (PrPC) exists in many non-neuronal tissues of sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

7 January 2021

Identification of five allelic variants of the sheep PrP gene and their association with natural scrapie

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

7 January 2021

Genotyping of German sheep with respect to scrapie susceptibility

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

7 January 2021

PrP gene polymorphism and natural scrapie in Icelandic sheep

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

7 January 2021

Scrapie-free Merino and Poll Dorset sheep from Australia and New Zealand have normal frequencies of scrapie-susceptible PrP genotypes

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

7 January 2021

Is scrapie solely a genetic disease?

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

7 January 2021

PrP genotype frequencies of the most dominant sheep breed in a country free from scrapie

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

7 January 2021

Amino acid polymorphisms of PrP with reference to onset of scrapie in Suffolk and Corriedale sheep in Japan

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

7 January 2021

Different allelic effects of the codons 136 and 171 of the prion protein gene in sheep with natural scrapie

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

7 January 2021

Natural scrapie and PrP genotype: case-control studies in British sheep

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

7 January 2021

Examination of the human prion protein-like gene doppel for genetic susceptibility to sporadic and variant Creutzfeldt-Jakob disease

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

7 January 2021

Quantitative trait loci affecting prion incubation time in mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-0463.2002.100105.X

7 January 2021

10.1034/J.1600-0463.2002.100105.X

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

12064254