A conformational change senses the strength of T cell receptor-ligand interaction during thymic selection (Q34687119)

3 August 2017

A conformational change senses the strength of T cell receptor-ligand interaction during thymic selection (English)

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3 August 2017

3

Balbino Alarcón

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author name string

Ruth M Risueño

series ordinal

1

1 reference

3 August 2017

Hisse M van Santen

series ordinal

2

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3 August 2017

language of work or name

English

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publication date

9 June 2006

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Proceedings of the National Academy of Sciences of the United States of America

3 August 2017

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3 August 2017

103

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3 August 2017

9625-9630

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3 August 2017

25

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describes a project that uses

3 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1480457/fullTextXML

inferred from PubMed Central ID database lookup

cites work

A requirement for sustained ERK signaling during thymocyte positive selection in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

The CD3epsilon proline-rich sequence, and its interaction with Nck, is not required for T cell development and function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Ligand-induced conformational change in the T-cell receptor associated with productive immune synapses

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

T cell receptor engagement by peptide-MHC ligands induces a conformational change in the CD3 complex of thymocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Signaling by the kinase MINK is essential in the negative selection of autoreactive thymocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Number of T reg cells that differentiate does not increase upon encounter of agonist ligand on thymic epithelial cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Identification and functional characterization of a novel human misshapen/Nck interacting kinase-related kinase, hMINK beta

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Dynamics of Cell Surface Molecules During T Cell Recognition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Signaling life and death in the thymus: timing is everything

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Initiation of TCR signaling: regulation within CD3 dimers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

A structural basis for the selection of dominant alphabeta T cell receptors in antiviral immunity

7 July 2018

1 reference

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Positive and negative selection of T cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

A T cell receptor CDR3beta loop undergoes conformational changes of unprecedented magnitude upon binding to a peptide/MHC class I complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

The specificity of TCR/pMHC interaction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Signal strength in thymic selection and lineage commitment.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

T cell receptor-MHC interactions up close

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Qualitative and quantitative differences in T cell receptor binding of agonist and antagonist ligands.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Dissociation of intracellular signaling pathways in response to partial agonist ligands of the T cell receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Coupling of T-cell activation with T-cell receptor assembly.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

The thymus selects the useful, neglects the useless and destroys the harmful

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

The CD3-gamma and CD3-delta subunits of the T cell antigen receptor can be expressed within distinct functional TCR/CD3 complexes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1480457

The influence of the thymic environment on the CD4-versus-CD8 T lineage decision.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0601785103

MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0601785103

T-cell-specific deletion of T-cell receptor transgenes allows functional rearrangement of endogenous α- and β-genes

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0601785103

Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

21 January 2018

1 reference

12 December 2020

1 reference

12 December 2020

Characterization of the region involved in CD3 pairwise interactions within the T cell receptor complex

1 reference

12 December 2020

Phosphorylation of T cell receptor zeta is regulated by a lipid dependent folding transition

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0601785103

1 reference

release_6jkqo236pjadzj4shigghn74a4

3 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6jkqo236pjadzj4shigghn74a4

24 November 2022

mapped directly with Wikidata item

PMCID

1480457

1 reference

3 August 2017

1 reference