GILT accelerates autoimmunity to the melanoma antigen tyrosinase-related protein 1. (Q34692289)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668223%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

GILT accelerates autoimmunity to the melanoma antigen tyrosinase-related protein 1 (English)

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8 February 2020

4

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8 February 2020

author name string

Matthew P Rausch

1

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8 February 2020

Kari R Irvine

2

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8 February 2020

Paul A Antony

3

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8 February 2020

Peter Cresswell

5

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8 February 2020

K Taraszka Hastings

6

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8 February 2020

language of work or name

English

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publication date

28 July 2010

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8 February 2020

published in

Journal of Immunology

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8 February 2020

volume

185

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8 February 2020

issue

5

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8 February 2020

page(s)

2828-2835

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Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma.

8 February 2020

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Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

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Mechanisms of spatial and temporal development of autoimmune vitiligo in tyrosinase-specific TCR transgenic mice

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Deletional self-tolerance to a melanocyte/melanoma antigen derived from tyrosinase is mediated by a radio-resistant cell in peripheral and mesenteric lymph nodes

7 July 2018

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7 July 2018

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Functional requirements for the lysosomal thiol reductase GILT in MHC class II-restricted antigen processing

7 July 2018

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7 July 2018

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Induction of CD4+ Th1 lymphocytes that recognize known and novel class II MHC restricted epitopes from the melanoma antigen gp100 by stimulation with recombinant protein

7 July 2018

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Cytotoxic T lymphocyte reactivity to gp100, MelanA/MART-1, and tyrosinase, in HLA-A2-positive vitiligo patients

7 July 2018

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Multiple HLA class II-restricted melanocyte differentiation antigens are recognized by tumor-infiltrating lymphocytes from a patient with melanoma

7 July 2018

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Expression of a "self-"antigen by human tumor cells enhances tumor antigen-specific CD4(+) T-cell function.

7 July 2018

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Molecular anatomy of tyrosinase and its related proteins: beyond the histidine-bound metal catalytic center.

7 July 2018

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Absence of gamma-interferon-inducible lysosomal thiol reductase in melanomas disrupts T cell recognition of select immunodominant epitopes

7 July 2018

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Defective antigen processing in GILT-free mice

7 July 2018

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Pmel17 initiates premelanosome morphogenesis within multivesicular bodies

7 July 2018

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Specific cytotoxic T lymphocyte responses against Melan-A/MART1, tyrosinase and gp100 in vitiligo by the use of major histocompatibility complex/peptide tetramers: the role of cellular immunity in the etiopathogenesis of vitiligo.

7 July 2018

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Gamma-interferon-inducible lysosomal thiol reductase (GILT). Maturation, activity, and mechanism of action

7 July 2018

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Identification of a MHC class II-restricted human gp100 epitope using DR4-IE transgenic mice

7 July 2018

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Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT)

7 July 2018

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Melan-A/MART-1(51-73) represents an immunogenic HLA-DR4-restricted epitope recognized by melanoma-reactive CD4(+) T cells

7 July 2018

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Vaccination with a recombinant vaccinia virus encoding a "self" antigen induces autoimmune vitiligo and tumor cell destruction in mice: requirement for CD4(+) T lymphocytes.

7 July 2018

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Melanoma cells present a MAGE-3 epitope to CD4(+) cytotoxic T cells in association with histocompatibility leukocyte antigen DR11.

7 July 2018

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7 July 2018

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High frequency of skin-homing melanocyte-specific cytotoxic T lymphocytes in autoimmune vitiligo

7 July 2018

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CD4+ T cells from peripheral blood of a melanoma patient recognize peptides derived from nonmutated tyrosinase

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Cutting edge: developmental up-regulation of IFN-gamma-inducible lysosomal thiol reductase expression leads to reduced T cell sensitivity and less severe autoimmunity.

7 July 2018

1 reference

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Inhibitory role of IFN-gamma-inducible lysosomal thiol reductase in T cell activation.

26 October 2018

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CD4 T cell-dependent autoimmunity against a melanocyte neoantigen induces spontaneous vitiligo and depends upon Fas-Fas ligand interactions.

26 October 2018

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26 October 2018

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Cathepsin S regulates the expression of cathepsin L and the turnover of gamma-interferon-inducible lysosomal thiol reductase in B lymphocytes

26 October 2018

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26 October 2018

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HLA-A2 Restricted, Melanocyte-Specific CD8+ T Lymphocytes Detected in Vitiligo Patients are Related to Disease Activity and are Predominantly Directed Against MelanA/MART1

26 October 2018

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12 December 2020

Vitiligo melanocytes in long-term culture show normal constitutive and cytokine-induced expression of intercellular adhesion molecule-1 and major histocompatibility complex class I and class II molecules

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Folding and maturation of tyrosinase-related protein-1 are regulated by the post-translational formation of disulfide bonds and by N-glycan processing

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Identifiers

DOI

10.4049/JIMMUNOL.1000945

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20668223%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

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8 February 2020

PubMed publication ID

20668223

1 reference