Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma. (Q33730129)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20156973%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma (English)

1 reference

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18 January 2020

8

1 reference

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18 January 2020

author name string

Ying Xie

1

1 reference

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18 January 2020

Akgül Akpinarli

2

1 reference

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18 January 2020

Charles Maris

3

1 reference

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18 January 2020

Edward L Hipkiss

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20156973%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Malcolm Lane

5

1 reference

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18 January 2020

Eun-Kyung M Kwon

6

1 reference

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18 January 2020

Pawel Muranski

7

1 reference

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18 January 2020

Paul Andrew Antony

9

1 reference

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18 January 2020

language of work or name

English

0 references

publication date

15 February 2010

1 reference

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Journal of Experimental Medicine

18 January 2020

published in

1 reference

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18 January 2020

volume

207

1 reference

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18 January 2020

page(s)

651-667

1 reference

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18 January 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20156973%20AND%20SRC:MED&resulttype=core&format=json

Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

18 January 2020

cites work

1 reference

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Adoptively transferred effector cells derived from naive rather than central memory CD8+ T cells mediate superior antitumor immunity.

21 June 2018

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Harnessing human dendritic cell subsets to design novel vaccines

21 June 2018

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Oncogenic stress sensed by the immune system: role of natural killer cell receptors

21 June 2018

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Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies

21 June 2018

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High-avidity autoreactive CD4+ T cells induce host CTL, overcome T(regs) and mediate tumor destruction

21 June 2018

1 reference

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Programming tumor-reactive effector memory CD8+ T cells in vitro obviates the requirement for in vivo vaccination.

21 June 2018

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Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

21 June 2018

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Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen

21 June 2018

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Adoptive immunotherapy of cancer using CD4(+) T cells

21 June 2018

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Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses

21 June 2018

1 reference

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Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells.

21 June 2018

1 reference

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Immune therapy for cancer

21 June 2018

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Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

21 June 2018

1 reference

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Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens

21 June 2018

1 reference

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Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma

21 June 2018

1 reference

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Treatment of metastatic melanoma with autologous CD4+ T cells against NY-ESO-1

21 June 2018

1 reference

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Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity

21 June 2018

1 reference

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Adoptive cell transfer: a clinical path to effective cancer immunotherapy

21 June 2018

1 reference

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Tumor-specific Th17-polarized cells eradicate large established melanoma

21 June 2018

1 reference

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CXCL9, but not CXCL10, promotes CXCR3-dependent immune-mediated kidney disease.

21 June 2018

1 reference

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Circulating tumor antigen-specific regulatory T cells in patients with metastatic melanoma

21 June 2018

1 reference

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Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice.

21 June 2018

1 reference

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T cell-encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection

21 June 2018

1 reference

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Taming cancer by inducing immunity via dendritic cells

21 June 2018

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Taking dendritic cells into medicine

21 June 2018

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An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2

21 June 2018

1 reference

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Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling.

21 June 2018

1 reference

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IL-15-induced human DC efficiently prime melanoma-specific naive CD8+ T cells to differentiate into CTL.

21 June 2018

1 reference

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CD4 cells can be more efficient at tumor rejection than CD8 cells

21 June 2018

1 reference

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CD4+ T cell migration into the cornea is reduced in CXCL9 deficient but not CXCL10 deficient mice following herpes simplex virus type 1 infection

21 June 2018

1 reference

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Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8 T cells

21 June 2018

1 reference

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Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

21 June 2018

1 reference

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Essential roles of DC-derived IL-15 as a mediator of inflammatory responses in vivo

21 June 2018

1 reference

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Cancer regression in patients after transfer of genetically engineered lymphocytes

21 June 2018

1 reference

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CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

21 June 2018

1 reference

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Interleukin-2 signals during priming are required for secondary expansion of CD8+ memory T cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

Adoptive immunotherapy for cancer: building on success

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

Interleukin-2-dependent mechanisms of tolerance and immunity in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

Genomic anatomy of the Tyrp1 (brown) deletion complex

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

Renewed interest in cancer immunotherapy with the tumor necrosis factor superfamily molecules

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

Central memory self/tumor-reactive CD8+ T cells confer superior antitumor immunity compared with effector memory T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD8+ T cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma

21 June 2018

1 reference

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Primary antitumor immune response mediated by CD4+ T cells

21 June 2018

1 reference

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CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

21 June 2018

1 reference

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Helper T cells, dendritic cells and CTL Immunity

21 June 2018

1 reference

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Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells.

21 June 2018

1 reference

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Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells

21 June 2018

1 reference

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CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

21 June 2018

1 reference

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Adoptive therapy with CD8(+) T cells: it may get by with a little help from its friends

21 June 2018

1 reference

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Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes

21 June 2018

1 reference

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Further checkpoints in Th1 development

21 June 2018

1 reference

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Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors

21 June 2018

1 reference

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Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses

21 June 2018

1 reference

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Progress in human tumour immunology and immunotherapy

21 June 2018

1 reference

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The role of MHC class II-restricted tumor antigens and CD4+ T cells in antitumor immunity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

Tumor-specific CD4+ T cells have a major "post-licensing" role in CTL mediated anti-tumor immunity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

Distinct role of antigen-specific T helper type 1 (Th1) and Th2 cells in tumor eradication in vivo

21 June 2018

1 reference

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CD4(+) T cells eliminate MHC class II-negative cancer cells in vivo by indirect effects of IFN-gamma

21 June 2018

1 reference

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CD4 T cells and their role in antitumor immune responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

The central role of CD4(+) T cells in the antitumor immune response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

TCR-MHC class II interaction is required for peripheral expansion of CD4 cells in a T cell-deficient host.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.

21 June 2018

1 reference

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Gamma-interferon transcriptionally regulates an early-response gene containing homology to platelet proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2839147

De novo HLA class II and enhanced HLA class I molecule expression in SV40 transfected human thyroid epithelial cells.

21 June 2018

1 reference

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Helper requirements for generation of effector CTL to islet beta cell antigens.

21 June 2018

1 reference

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Help for cytotoxic-T-cell responses is mediated by CD40 signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091921

Selective stimulation of T cell subsets with antibody-cytokine immune complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091921

Autoimmunity and tumor immunity induced by immune responses to mutations in self

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091921

Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091921

CD4+ T cell--mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoietic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091921

A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091921

Editorial overview: lymphocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091921

CD40 activation in vivo overcomes peptide-induced peripheral cytotoxic T-lymphocyte tolerance and augments anti-tumor vaccine efficacy

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20091921

Regulatory T cells control dendritic cell/NK cell cross-talk in lymph nodes at the steady state by inhibiting CD4+ self-reactive T cells

21 January 2018

1 reference

12 December 2020

IL-7/anti-IL-7 mAb complexes restore T cell development and induce homeostatic T Cell expansion without lymphopenia

1 reference

12 December 2020

Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response

1 reference

12 December 2020

Priming of naive T cells inside tumors leads to eradication of established tumors

1 reference

12 December 2020

CD4+ T cell clones specific for the human p97 melanoma-associated antigen can eradicate pulmonary metastases from a murine tumor expressing the p97 antigen

1 reference

12 December 2020

Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40

1 reference

12 December 2020

Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming

1 reference

12 December 2020

Lymphopenia and interleukin-2 therapy alter homeostasis of CD4+CD25+ regulatory T cells

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20091921

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20156973%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20156973%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference