Extracellular Regulation of Myostatin: A Molecular Rheostat for Muscle Mass (Q34694932)

4 August 2017

title

Extracellular Regulation of Myostatin: A Molecular Rheostat for Muscle Mass (English)

1 reference

4 August 2017

Se-Jin Lee

1

1 reference

4 August 2017

publication date

1 January 2010

1 reference

Immunology, endocrine & metabolic agents in medicinal chemistry

4 August 2017

published in

1 reference

4 August 2017

volume

10

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4 August 2017

page(s)

183-194

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Follistatin gene delivery enhances muscle growth and strength in nonhuman primates

4 August 2017

cites work

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7 July 2018

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Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity

7 July 2018

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Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

7 July 2018

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7 July 2018

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Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy

7 July 2018

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Proteomic identification and functional validation of activins and bone morphogenetic protein 11 as candidate novel muscle mass regulators

7 July 2018

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The Structure of FSTL3·Activin A Complex DIFFERENTIAL BINDING OF N-TERMINAL DOMAINS INFLUENCES FOLLISTATIN-TYPE ANTAGONIST SPECIFICITY

7 July 2018

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Both WFIKKN1 and WFIKKN2 have high affinity for growth and differentiation factors 8 and 11

7 July 2018

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Differential antagonism of activin, myostatin and growth and differentiation factor 11 by wild-type and mutant follistatin

7 July 2018

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Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors

7 July 2018

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Genetic analysis of the role of proteolysis in the activation of latent myostatin

7 July 2018

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Transgenic expression of a myostatin inhibitor derived from follistatin increases skeletal muscle mass and ameliorates dystrophic pathology in mdx mice

7 July 2018

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Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways

7 July 2018

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Decorin gene transfer promotes muscle cell differentiation and muscle regeneration

7 July 2018

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The bone morphogenetic protein 1/Tolloid-like metalloproteinases

7 July 2018

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A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs

7 July 2018

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FSTL3 deletion reveals roles for TGF-beta family ligands in glucose and fat homeostasis in adults

7 July 2018

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Analysis of pancreatic endocrine development in GDF11-deficient mice

7 July 2018

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The function of growth/differentiation factor 11 (Gdf11) in rostrocaudal patterning of the developing spinal cord

7 July 2018

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A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep

7 July 2018

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Expression of the TGF-beta family of ligands is developmentally regulated in skeletal muscle of neonatal rats

7 July 2018

1 reference

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Decorin binds myostatin and modulates its activity to muscle cells

7 July 2018

1 reference

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Regulation of muscle growth by multiple ligands signaling through activin type II receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

The structure of the follistatin:activin complex reveals antagonism of both type I and type II receptor binding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Activin A inhibits formation of skeletal muscle during chick development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

GDF11 controls the timing of progenitor cell competence in developing retina

7 July 2018

1 reference

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Transgenic engineering of male-specific muscular hypertrophy

7 July 2018

1 reference

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GDF11 modulates NGN3+ islet progenitor cell number and promotes beta-cell differentiation in pancreas development

7 July 2018

1 reference

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Regulation of muscle mass by myostatin

7 July 2018

1 reference

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Myostatin mutation associated with gross muscle hypertrophy in a child

7 July 2018

1 reference

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Deacetylase inhibitors increase muscle cell size by promoting myoblast recruitment and fusion through induction of follistatin

7 July 2018

1 reference

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Activation of latent myostatin by the BMP-1/tolloid family of metalloproteinases

7 July 2018

1 reference

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hSGT interacts with the N-terminal region of myostatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Myostatin Signals through a Transforming Growth Factor β-Like Signaling Pathway To Block Adipogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Regulation of metanephric kidney development by growth/differentiation factor 11

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Regulation of myostatin in vivo by growth and differentiation factor-associated serum protein-1: a novel protein with protease inhibitor and follistatin domains

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Inhibition of myostatin in adult mice increases skeletal muscle mass and strength

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Autoregulation of neurogenesis by GDF11

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Activins, inhibins, and follistatins: from endocrinology to signaling. A paradigm for the new millennium

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Titin-cap associates with, and regulates secretion of, Myostatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

The myostatin propeptide and the follistatin-related gene are inhibitory binding proteins of myostatin in normal serum

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Induction of cachexia in mice by systemically administered myostatin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Regulation of myostatin activity and muscle growth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Evolution and classification of cystine knot-containing hormones and related extracellular signaling molecules

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

A human protein containing multiple types of protease-inhibitory modules

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Identification and characterization of a novel follistatin-like protein as a binding protein for the TGF-beta family

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Regulation of anterior/posterior patterning of the axial skeleton by growth/differentiation factor 11

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Myostatin, a transforming growth factor-beta superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

A novel BMP expressed in developing mouse limb, spinal cord, and tail bud is a potent mesoderm inducer in Xenopus embryos

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

FLRG (follistatin-related gene), a new target of chromosomal rearrangement in malignant blood disorders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Molecular definition of an allelic series of mutations disrupting the myostatin function and causing double-muscling in cattle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Cleavage of the BMP-4 antagonist chordin by zebrafish tolloid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Production of a DPP activity gradient in the early Drosophila embryo through the opposing actions of the SOG and TLD proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Double muscling in cattle due to mutations in the myostatin gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Failure of ventral body wall closure in mouse embryos lacking a procollagen C-proteinase encoded by Bmp1, a mammalian gene related to Drosophila tolloid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Multiple defects and perinatal death in mice deficient in follistatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Isolation and partial characterization of follistatin: a single-chain Mr 35,000 monomeric protein that inhibits the release of follicle-stimulating hormone

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Pituitary FSH is released by a heterodimer of the beta-subunits from the two forms of inhibin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Purification and characterization of an FSH releasing protein from porcine ovarian follicular fluid

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Activin-binding protein from rat ovary is follistatin.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Adeno-associated virus-8-mediated intravenous transfer of myostatin propeptide leads to systemic functional improvements of slow but not fast muscle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Myostatin propeptide gene delivery by adeno-associated virus serotype 8 vectors enhances muscle growth and ameliorates dystrophic phenotypes in mdx mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Identification of a novel pool of extracellular pro-myostatin in skeletal muscle.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Expression, purification, renaturation and activation of fish myostatin expressed in Escherichia coli: facilitation of refolding and activity inhibition by myostatin prodomain.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

AAV-mediated delivery of a mutated myostatin propeptide ameliorates calpain 3 but not alpha-sarcoglycan deficiency

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Proteolytic processing of myostatin is auto-regulated during myogenesis.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Follistatin complexes Myostatin and antagonises Myostatin-mediated inhibition of myogenesis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Refolding and purification of unprocessed porcine myostatin expressed in Escherichia coli

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Characterization and identification of the inhibitory domain of GDF-8 propeptide

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Functional improvement of dystrophic muscle by myostatin blockade.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

The mammalian Tolloid-like 1 gene, Tll1, is necessary for normal septation and positioning of the heart.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Opposing effects of activin A and follistatin on developing skeletal muscle cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

The dorsalizing and neural inducing gene follistatin is an antagonist of BMP-4.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Requirement for activin A and transforming growth factor--beta 1 pro-regions in homodimer assembly.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060380

Expression of myostatin pro domain results in muscular transgenic mice

26 October 2018

1 reference

12 December 2020

Difference between follistatin isoforms in the inhibition of activin signalling: activin neutralizing activity of follistatin isoforms is dependent on their affinity for activin

1 reference

12 December 2020

Myostatin propeptide-mediated amelioration of dystrophic pathophysiology

1 reference

12 December 2020

A missense mutant myostatin causes hyperplasia without hypertrophy in the mouse muscle

1 reference

12 December 2020

The isolation of polypeptides with FSH suppressing activity from bovine follicular fluid which are structurally different to inhibin

1 reference

12 December 2020

Molecular, cellular and physiological investigation of myostatin propeptide-mediated muscle growth in adult mice

1 reference

12 December 2020

Dominant negative myostatin produces hypertrophy without hyperplasia in muscle

1 reference

12 December 2020

10.2174/187152210793663748

Identifiers

DOI

1 reference

4 August 2017

1 reference

4 August 2017

1 reference