A computational protocol for the integration of the monotopic protein prostaglandin H2 synthase into a phospholipid bilayer (Q34698519)

4 August 2017

title

A computational protocol for the integration of the monotopic protein prostaglandin H2 synthase into a phospholipid bilayer (English)

1 reference

4 August 2017

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computational biology

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2

Peter V Coveney

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4 August 2017

Philip W Fowler

1

1 reference

4 August 2017

language of work or name

English

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publication date

21 April 2006

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4 August 2017

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4 August 2017

volume

91

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4 August 2017

issue

2

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4 August 2017

page(s)

401-410

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Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis

4 August 2017

cites work

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling

7 July 2018

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7 July 2018

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Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders

7 July 2018

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7 July 2018

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A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitors

7 July 2018

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Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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The membrane binding domains of prostaglandin endoperoxide H synthases 1 and 2. Peptide mapping and mutational analysis

7 July 2018

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7 July 2018

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Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents

7 July 2018

1 reference

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Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2

7 July 2018

1 reference

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7 July 2018

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Role of Val509 in time-dependent inhibition of human prostaglandin H synthase-2 cyclooxygenase activity by isoform-selective agents

7 July 2018

1 reference

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Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic

7 July 2018

1 reference

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The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1

7 July 2018

1 reference

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Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain

7 July 2018

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Specificity of expression and effects of eicosanoid mediators in normal physiology and human diseases 1

7 July 2018

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Intracellular protein topogenesis

7 July 2018

1 reference

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On the mechanism of the biosynthesis of prostaglandins E-1 and F-1-alpha

7 July 2018

1 reference

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Primary structure of prostaglandin G/H synthase from sheep vesicular gland determined from the complementary DNA sequence

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483072

Properties of integral membrane protein structures: derivation of an implicit membrane potential.

7 July 2018

1 reference

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Anchoring of a monotopic membrane protein: the binding of prostaglandin H2 synthase-1 to the surface of a phospholipid bilayer.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1483072

The dynamics of prostaglandin H synthases. Studies with prostaglandin h synthase 2 Y355F unmask mechanisms of time-dependent inhibition and allosteric activation

26 October 2018

1 reference

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A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.

26 October 2018

1 reference

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All-atom empirical potential for molecular modeling and dynamics studies of proteins

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16632499

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Photolabeling of Prostaglandin Endoperoxide H Synthase-1 with 3-Trifluoro-3-(m-Iiodophenyl)diazirine as a Probe of Membrane Association and the Cyclooxygenase Active Site

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16632499

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Conversion of prostaglandin G/H synthase-1 into an enzyme sensitive to PGHS-2-selective inhibitors by a double His513 --> Arg and Ile523 --> val mutation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16632499

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1529/BIOPHYSJ.105.077784

1 reference

4 August 2017

1 reference

4 August 2017

1 reference