Off-target effects by siRNA can induce toxic phenotype (Q34703017)

4 August 2017

Off-target effects by siRNA can induce toxic phenotype (English)

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4 August 2017

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Yuriy Fedorov

1

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4 August 2017

Emily M Anderson

2

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4 August 2017

Amanda Birmingham

3

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4 August 2017

Angela Reynolds

4

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4 August 2017

Jon Karpilow

5

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4 August 2017

Kathryn Robinson

6

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4 August 2017

Devin Leake

7

1 reference

4 August 2017

William S Marshall

8

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4 August 2017

Anastasia Khvorova

9

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4 August 2017

language of work or name

English

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publication date

8 May 2006

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4 August 2017

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4 August 2017

12

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4 August 2017

1188-1196

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4 August 2017

7

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Position-specific chemical modification of siRNAs reduces "off-target" transcript silencing

4 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

3' UTR seed matches, but not overall identity, are associated with RNAi off-targets

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

Involvement of microRNA in AU-rich element-mediated mRNA instability

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

Kinetic analysis of the RNAi enzyme complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

Rational siRNA design for RNA interference

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

Expression profiling reveals off-target gene regulation by RNAi

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

RNA-binding analyses of HuC and HuD with the VEGF and c-myc 3'-untranslated regions using a novel ELISA-based assay

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

A branched DNA signal amplification assay for quantification of nucleic acid targets below 100 molecules/ml

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

Hel-N1: an autoimmune RNA-binding protein with specificity for 3' uridylate-rich untranslated regions of growth factor mRNAs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

Selection of a subset of mRNAs from combinatorial 3' untranslated region libraries using neuronal RNA-binding protein Hel-N1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

Expression of a novel immediate early gene during 12-O-tetradecanoylphorbol-13-acetate-induced macrophagic differentiation of HL-60 cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484448

RNA oligonucleotide synthesis via 5'-silyl-2'-orthoester chemistry

7 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16682561

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16682561

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1261/RNA.28106

1 reference

4 August 2017

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4 August 2017

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