SmgGDS regulates cell proliferation, migration, and NF-kappaB transcriptional activity in non-small cell lung carcinoma (Q34704519)

4 August 2017

title

SmgGDS regulates cell proliferation, migration, and NF-kappaB transcriptional activity in non-small cell lung carcinoma (English)

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4 August 2017

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Gaik Wei Tew

1

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4 August 2017

Ellen L Lorimer

2

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4 August 2017

Tracy J Berg

3

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4 August 2017

Huiying Zhi

4

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4 August 2017

Rongshan Li

5

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4 August 2017

Carol L Williams

6

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4 August 2017

language of work or name

English

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publication date

19 October 2007

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Journal of Biological Chemistry

4 August 2017

published in

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4 August 2017

volume

283

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4 August 2017

issue

2

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4 August 2017

page(s)

963-976

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4 August 2017

cites work

Cancer statistics, 2006

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Loss of RhoB expression in human lung cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Histone deacetylase 1 represses the small GTPase RhoB expression in human nonsmall lung carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

A definitive role of RhoC in metastasis of orthotopic lung cancer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Identification of differentially expressed genes in human lung squamous cell carcinoma using suppression subtractive hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Farnesyl transferase inhibitors for patients with lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Cooperation between PKC-alpha and PKC-epsilon in the regulation of JNK activation in human lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Endogenous oncogenic K-ras(G12D) stimulates proliferation and widespread neoplastic and developmental defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Identification of bronchioalveolar stem cells in normal lung and lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Stem cells for lung cancer?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Rap1 GTPase: Functions, Regulation, and Malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Rap1 regulates the formation of E-cadherin-based cell-cell contacts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Local activation of Rap1 contributes to directional vascular endothelial cell migration accompanied by extension of microtubules on which RAPL, a Rap1-associating molecule, localizes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Trading spaces: Rap, Rac, and Rho as architects of transendothelial migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

21 January 2018

Rho proteins and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Rho signals to cell growth and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

The role of Rho-associated kinase in differential regulation by statins of interleukin-1beta- and lipopolysaccharide-mediated nuclear factor kappaB activation and inducible nitric-oxide synthase gene expression in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

12/15-lipoxygenase regulates intercellular adhesion molecule-1 expression and monocyte adhesion to endothelium through activation of RhoA and nuclear factor-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

The cardenolide UNBS1450 is able to deactivate nuclear factor kappaB-mediated cytoprotective effects in human non-small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

17-allylamino-17-demethoxygeldanamycin synergistically potentiates tumor necrosis factor-induced lung cancer cell death by blocking the nuclear factor-kappaB pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Modulation of antiapoptotic cell signaling pathways in non-small cell lung cancer: the role of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Inhibition of NF-kappaB sensitizes non-small cell lung cancer cells to chemotherapy-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Chromium(VI) inhibits the transcriptional activity of nuclear factor-kappaB by decreasing the interaction of p65 with cAMP-responsive element-binding protein-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

N-Acetyl-L-cysteine enhances apoptosis through inhibition of nuclear factor-kappaB in hypoxic murine embryonic fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Nuclear factor-kappaB induced by doxorubicin is deficient in phosphorylation and acetylation and represses nuclear factor-kappaB-dependent transcription in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Novel mechanism of the co-regulation of nuclear transport of SmgGDS and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

The polybasic region of Ras and Rho family small GTPases: a regulator of protein interactions and membrane association and a site of nuclear localization signal sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

A stimulatory GDP/GTP exchange protein for smg p21 is active on the post-translationally processed form of c-Ki-ras p21 and rhoA p21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

SmgGDS stabilizes nucleotide-bound and -free forms of the Rac1 GTP-binding protein and stimulates GTP/GDP exchange through a substituted enzyme mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 Cells Induces DNA Synthesis and Morphological Changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Cell culture block array for immunocytochemical study of protein expression in cultured cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Involvement of the muscarinic acetylcholine receptor in inhibition of cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Targeting the epigenome for the treatment and prevention of lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

NF-kappaB and cell-cycle regulation: the cyclin connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Nuclear factor-kappaB: the enemy within

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Autocrine and paracrine regulation of interleukin-8 expression in lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

IKK/NF-kappaB signaling: balancing life and death--a new approach to cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Nuclear factor-kappaB in cancer development and progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Nuclear factor kappa B is a promising therapeutic target in inflammatory lung disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Response of rat alveolar type II cells and human lung tumor cells towards oxidative stress induced by hydrogen peroxide and paraquat

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Signaling pathways controlling the production of inflammatory mediators in response to crystalline silica exposure: role of reactive oxygen/nitrogen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Redox modulation of chromatin remodeling: impact on histone acetylation and deacetylation, NF-kappaB and pro-inflammatory gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Tumor necrosis factor-alpha increases reactive oxygen species by inducing spermine oxidase in human lung epithelial cells: a potential mechanism for inflammation-induced carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Mutual cross-talk between reactive oxygen species and nuclear factor-kappa B: molecular basis and biological significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

A NF-kappaB p65 subunit is indispensable for activating manganese superoxide: dismutase gene transcription mediated by tumor necrosis factor-alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Superoxide dismutases in the lung and human lung diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Superoxide dismutases in malignant cells and human tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Increased staining for phospho-Akt, p65/RELA and cIAP-2 in pre-neoplastic human bronchial biopsies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Cytokinesis: welcome to the Rho zone

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

p53-mediated activation of miRNA34 candidate tumor-suppressor genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M707526200

21 January 2018

Identifiers

DOI

10.1074/JBC.M707526200

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4 August 2017

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