Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer (Q34705149)

4 August 2017

Concurrent genetic alterations in DNA polymerase proofreading and mismatch repair in human colorectal cancer (English)

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4 August 2017

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10

Yoshihiko Maehara

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4 August 2017

Rintaro Yoshida

1

1 reference

4 August 2017

Kaname Miyashita

2

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4 August 2017

Mayuko Inoue

3

1 reference

4 August 2017

Akiyoshi Shimamoto

4

1 reference

4 August 2017

Zhao Yan

5

1 reference

4 August 2017

Akinori Egashira

6

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4 August 2017

Eiji Oki

7

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4 August 2017

Yoshishiro Kakeji

8

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4 August 2017

Shinya Oda

9

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4 August 2017

15 December 2010

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European Journal of Human Genetics

4 August 2017

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4 August 2017

19

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4 August 2017

3

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4 August 2017

320-325

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https://scigraph.springernature.com/pub.10.1038/ejhg.2010.216

4 August 2017

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Proofreading exonuclease activity of human DNA polymerase delta and its effects on lesion-bypass DNA synthesis.

7 July 2018

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Liver metastasis models of colon cancer for evaluation of drug efficacy using NOD/Shi-scid IL2Rgammanull (NOG) mice.

7 July 2018

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The genomic landscapes of human breast and colorectal cancers

7 July 2018

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Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

7 July 2018

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The consensus coding sequences of human breast and colorectal cancers

7 July 2018

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Two modes of microsatellite instability in human cancer: differential connection of defective DNA mismatch repair to dinucleotide repeat instability.

7 July 2018

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Multiple mutations and cancer

7 July 2018

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High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading

7 July 2018

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A mutator phenotype in cancer.

7 July 2018

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APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits"

7 July 2018

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DNA polymerase epsilon catalytic domains are dispensable for DNA replication, DNA repair, and cell viability

7 July 2018

1 reference

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Mutated gene-specific phenotypes of dinucleotide repeat instability in human colorectal carcinoma cell lines deficient in DNA mismatch repair

7 July 2018

1 reference

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Structural organization and splice variants of the POLE1 gene encoding the catalytic subunit of human DNA polymerase epsilon

7 July 2018

1 reference

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Detection of mutations in the DNA polymerase delta gene of human sporadic colorectal cancers and colon cancer cell lines

7 July 2018

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Mutation in the mismatch repair gene Msh6 causes cancer susceptibility

7 July 2018

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Screening the p53 status of human cell lines using a yeast functional assay

7 July 2018

1 reference

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Precise assessment of microsatellite instability using high resolution fluorescent microsatellite analysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Base transitions dominate the mutational spectrum of a transgenic reporter gene in MSH2 deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Spectra of spontaneous mutations at the hprt locus in colorectal carcinoma cell lines defective in mismatch repair.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Differences in the spectrum of spontaneous mutations in the hprt gene between tumor cells of the microsatellite mutator phenotype

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines.

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase epsilon

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Altered growth of human colon cancer cell lines disrupted at activated Ki-ras

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Pathway correcting DNA replication errors in Saccharomyces cerevisiae

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Cloning of a mouse cDNA encoding DNA polymerase delta: refinement of the homology boxes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Reconstitution of complete SV40 DNA replication with purified replication factors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Mutation of a mutL homolog in hereditary colon cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Mutator phenotypes in human colorectal carcinoma cell lines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

DNA mismatch binding defects, DNA damage tolerance, and mutator phenotypes in human colorectal carcinoma cell lines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Polymerase delta variants in RER colorectal tumours

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Yeast DNA polymerases and their role at the replication fork.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Mutations of GTBP in genetically unstable cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Mutation rate: some biological and biochemical considerations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: a fidelity subunit for DNA replication

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Isolation of conditional lethal mutator mutants of Escherichia coli by localized mutagenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Fidelity of DNA synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Comparative rates of spontaneous mutation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Spectra of spontaneous mutations in Escherichia coli strains defective in mismatch correction: the nature of in vivo DNA replication errors.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

A genetic model for colorectal tumorigenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Mechanisms and biological effects of mismatch repair

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Molecular cloning of the cDNA for the catalytic subunit of human DNA polymerase delta

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Bacterial mutator genes and the control of spontaneous mutation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Structure of the gene for the catalytic subunit of human DNA polymerase delta (POLD1).

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2010.216

Structural organization and splice variants of the POLE1 gene encoding the catalytic subunit of human DNA polymerase ε

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2010.216

Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2010.216

cDNA and structural organization of the gene Pole1 for the mouse DNA polymerase epsilon catalytic subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2010.216

Genetic variation in the DNA repair genes is predictive of outcome in lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEJHG.2010.216

Structure of the human MLH1 locus and analysis of a large hereditary nonpolyposis colorectal carcinoma kindred for mlh1 mutations.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061989

Mutator phenotype in Msh2-deficient murine embryonic fibroblasts

26 October 2018

1 reference

12 December 2020

Microsatellite instability in human solid tumors

1 reference

12 December 2020

Exclusive KRAS mutation in microsatellite-unstable human colorectal carcinomas with sequence alterations in the DNA mismatch repair gene, MLH1

1 reference

12 December 2020

Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice

1 reference

12 December 2020

Temperature-dependent mutational specificity of an Escherichia coli mutator, dnaQ49, defective in 3'----5' exonuclease (proofreading) activity

1 reference

12 December 2020

The 3'-->5' exonucleases of both DNA polymerases delta and epsilon participate in correcting errors of DNA replication in Saccharomyces cerevisiae

1 reference

12 December 2020

Mismatch repair gene defects in sporadic colorectal cancers with microsatellite instability

1 reference

12 December 2020

Identifiers

DOI

10.1038/EJHG.2010.216

1 reference

4 August 2017

1 reference

4 August 2017

1 reference