Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell (Q34083615)

30 July 2017

1 reference

title

Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell (English)

1 reference

30 July 2017

1 reference

P Maechler

1

1 reference

PubMed ID

11080250

30 July 2017

C B Wollheim

series ordinal

2

1 reference

PubMed ID

11080250

30 July 2017

language of work or name

English

0 references

publication date

1 November 2000

1 reference

30 July 2017

8

1 reference

inferred from page(s)

published in

Journal of Physiology

1 reference

30 July 2017

529 Pt 1

1 reference

30 July 2017

49-56

1 reference

Autonomic regulation of islet hormone secretion--implications for health and disease

30 July 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Molecular or pharmacologic perturbation of the link between glucose and lipid metabolism is without effect on glucose-stimulated insulin secretion. A re-evaluation of the long-chain acyl-CoA hypothesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Uptake of glutamate into synaptic vesicles by an inorganic phosphate transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Regulation of pancreatic beta-cell mitochondrial metabolism: influence of Ca2+, substrate and ADP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

On the role of the calcium transport cycle in heart and other mammalian mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Two sites of glucose control of insulin release with distinct dependence on the energy state in pancreatic B-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Contributions of mitochondria to animal physiology: from homeostatic sensor to calcium signalling and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Ethidium bromide-induced inhibition of mitochondrial gene transcription suppresses glucose-stimulated insulin release in the mouse pancreatic beta-cell line betaHC9.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Increased tricarboxylic acid cycle flux in rat brain during forepaw stimulation detected with 1H[13C]NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Molecular mechanisms and regulation of insulin exocytosis as a paradigm of endocrine secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Maternally inherited diabetes and deafness: a new diabetes subtype

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Modulation of glutamate generation in mitochondria affects hormone secretion in INS-1E beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Desensitization of mitochondrial Ca2+ and insulin secretion responses in the beta cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Glutamate production in islets of Langerhans: properties of phosphate-activated glutaminase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Metabolic coupling factors in pancreatic beta-cell signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Glutamate transport and storage in synaptic vesicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

The pancreatic beta-cell as a fuel sensor: an electrophysiologist's viewpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Metabolic fate of glucose in purified islet cells. Glucose-regulated anaplerosis in beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Sur1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Hexose metabolism in pancreatic islets. Participation of Ca2(+)-sensitive 2-ketoglutarate dehydrogenase in the regulation of mitochondrial function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo 13C NMR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Mitochondrial DNA is required for regulation of glucose-stimulated insulin secretion in a mouse pancreatic beta cell line, MIN6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Identification of a vesicular glutamate transporter that defines a glutamatergic phenotype in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Functional and morphological abnormalities of mitochondria harbouring the tRNA(Leu)(UUR) mutation in mitochondrial DNA derived from patients with maternally inherited diabetes and deafness (MIDD) and progressive kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Differential expression of glutamate receptor subtypes in rat pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Beta-cell mitochondria in the regulation of insulin secretion: a new culprit in type II diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1469-7793.2000.00049.X

Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

What couples glycolysis to mitochondrial signal generation in glucose-stimulated insulin secretion?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

The role of long-chain fatty acyl-CoA esters in beta-cell signal transduction

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Newer aspects of glutamine/glutamate metabolism: the role of acute pH changes

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Glucose regulation of glutaminolysis and its role in insulin secretion

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Creation and characterization of a mitochondrial DNA-depleted pancreatic beta-cell line: impaired insulin secretion induced by glucose, leucine, and sulfonylureas

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Mechanisms of inhibition of insulin release

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Glucose-stimulated insulin secretion correlates with changes in mitochondrial and cytosolic Ca2+ in aequorin-expressing INS-1 cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

L-glutamate dehydrogenases: distribution, properties and mechanism.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Direct control of exocytosis by receptor-mediated activation of the heterotrimeric GTPases Gi and G(o) or by the expression of their active G alpha subunits

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

High content of mitochondrial glycerol-3-phosphate dehydrogenase in pancreatic islets and its inhibition by diazoxide.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Role of glucose as a regulator and precursor of amino acids in the pancreatic beta-cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Relation between mitochondrial calcium transport and control of energy metabolism

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Banting lecture 1990. Beta-cells in type II diabetes mellitus

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

ATP-dependent and ATP-independent pathways of exocytosis revealed by interchanging glutamate and chloride as the major anion in permeabilized mast cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Evidence that glucose can control insulin release independently from its action on ATP-sensitive K+ channels in mouse B cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Malonyl-CoA and long chain acyl-CoA esters as metabolic coupling factors in nutrient-induced insulin secretion

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Evidence for a glutamate receptor of the AMPA subtype which mediates insulin release from rat perfused pancreas

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Dual Functional Role of Membrane Depolarization/Ca2+ Influx in Rat Pancreatic B-Cell

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2270172

Glutamate is not a messenger in insulin secretion

28 October 2018

1 reference

12 December 2020

Methodological approaches to studies on the pancreatic islets

1 reference

12 December 2020

Levels of α-Ketoglutarate and Glutamate in Stimulated Pancreatic β-Cells

1 reference

12 December 2020

The stimulus-secretion coupling of glucose-induced insulin release. XLVI. Physiological role of L-glutamine as a fuel for pancreatic islets

1 reference

12 December 2020

Regulation of insulin release by factors that also modify glutamate dehydrogenase

1 reference

12 December 2020

Insulinotropic action of glutamic acid dimethyl ester

1 reference

12 December 2020

Slow and fast oscillations of cytoplasmic Ca2+ in pancreatic islets correspond to pulsatile insulin release

1 reference

12 December 2020

Expression and role of ionotropic glutamate receptors in pancreatic islet cells

1 reference

12 December 2020

Feasibility of a mitochondrial pyruvate malate shuttle in pancreatic islets. Further implication of cytosolic NADPH in insulin secretion

1 reference

12 December 2020

In situ characterization of islets in diabetes with a mitochondrial DNA mutation at nucleotide position 3243

1 reference

12 December 2020

Role of NADH shuttle system in glucose-induced activation of mitochondrial metabolism and insulin secretion

1 reference

12 December 2020

Hyperinsulinism-hyperammonemia syndrome caused by mutant glutamate dehydrogenase accompanied by novel enzyme kinetics

1 reference

12 December 2020

10.1111/J.1469-7793.2000.00049.X

Identifiers

DOI

1 reference

30 July 2017

0 references

1 reference

PubMed ID

11080250