The notch pathway: modulation of cell fate decisions in hematopoiesis (Q34719214)

4 August 2017

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title

The notch pathway: modulation of cell fate decisions in hematopoiesis (English)

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4 August 2017

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Ohishi K

1

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4 August 2017

Varnum-Finney B

series ordinal

2

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4 August 2017

Bernstein ID

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3

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4 August 2017

1 June 2002

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International Journal of Hematology

4 August 2017

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4 August 2017

75

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4 August 2017

5

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4 August 2017

449-459

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https://scigraph.springernature.com/pub.10.1007/bf02982106

4 August 2017

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cites work

Signalling downstream of activated mammalian Notch

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12 December 2020

The Drosophila homolog of the mouse mammary oncogene int-1 is identical to the segment polarity gene wingless

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12 December 2020

LIM protein KyoT2 negatively regulates transcription by association with the RBP-J DNA-binding protein

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12 December 2020

Molecular interaction between TLE1 and the carboxyl-terminal domain of HES-1 containing the WRPW motif

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12 December 2020

Engineered truncations in the Drosophila mastermind protein disrupt Notch pathway function

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12 December 2020

A homolog of Drosophila Notch expressed during mammalian development

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12 December 2020

Mastermind acts downstream of notch to specify neuronal cell fates in the Drosophila central nervous system.

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12 December 2020

The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch

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12 December 2020

Mouse jagged1 physically interacts with notch2 and other notch receptors. Assessment by quantitative methods

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12 December 2020

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

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12 December 2020

Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene

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12 December 2020

Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

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12 December 2020

Interchangeability of Caenorhabditis elegans DSL proteins and intrinsic signalling activity of their extracellular domains in vivo.

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12 December 2020

Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47

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12 December 2020

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium

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12 December 2020

Notch1 and T-cell development: insights from conditional knockout mice

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12 December 2020

Fringe forms a complex with Notch

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12 December 2020

Notch signaling during vascular development

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12 December 2020

Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins

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12 December 2020

Cell autonomy of lin-12 function in a cell fate decision in C. elegans.

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12 December 2020

Serrate-mediated activation of Notch is specifically blocked by the product of the gene fringe in the dorsal compartment of the Drosophila wing imaginal disc.

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12 December 2020

Progressive lineage analysis by cell sorting and culture identifies FLK1+VE-cadherin+ cells at a diverging point of endothelial and hemopoietic lineages

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12 December 2020

Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila

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12 December 2020

Molecular analysis of the neurogenic locus mastermind of Drosophila melanogaster

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12 December 2020

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

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12 December 2020

Notch signalling acts in postmitotic avian myogenic cells to control MyoD activation

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12 December 2020

Modulated expression of notch1 during thymocyte development.

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12 December 2020

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12 December 2020

Notch and the immune system.

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12 December 2020

The Notch/Jagged pathway inhibits proliferation of human hematopoietic progenitors in vitro

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12 December 2020

Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells.

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12 December 2020

Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength

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12 December 2020

CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex

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12 December 2020

Maintenance of somite borders in mice requires the Delta homologue DII1.

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12 December 2020

A human protein with sequence similarity to Drosophila mastermind coordinates the nuclear form of notch and a CSL protein to build a transcriptional activator complex on target promoters

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12 December 2020

The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells.

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12 December 2020

The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage

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12 December 2020

Ligand endocytosis drives receptor dissociation and activation in the Notch pathway

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12 December 2020

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD.

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12 December 2020

Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

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12 December 2020

LIN-12/Notch signaling: lessons from worms and flies

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12 December 2020

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

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12 December 2020

Expression of notch receptors, notch ligands, and fringe genes in hematopoiesis.

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12 December 2020

Jagged: a mammalian ligand that activates Notch1

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12 December 2020

Mechanisms of angiogenesis

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12 December 2020

Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis

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12 December 2020

Notch2: a second mammalian Notch gene

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12 December 2020

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors

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12 December 2020

Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation

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12 December 2020

Notch signaling: from the outside in

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12 December 2020

Single amino acid substitutions in EGF-like elements of Notch and Delta modify Drosophila development and affect cell adhesion in vitro

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12 December 2020

Fringe is a glycosyltransferase that modifies Notch

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12 December 2020

Notch1 is required for the coordinate segmentation of somites

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12 December 2020

Delta-induced Notch signaling mediated by RBP-J inhibits MyoD expression and myogenesis

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12 December 2020

The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients

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12 December 2020

Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium

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12 December 2020

Dll4, a novel Notch ligand expressed in arterial endothelium

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12 December 2020

Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

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12 December 2020

Recognition sequence of a highly conserved DNA binding protein RBP-J kappa

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12 December 2020

Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2.

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12 December 2020

Correlating notch signaling with thymocyte maturation

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12 December 2020

A common precursor for hematopoietic and endothelial cells.

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12 December 2020

Notch signalling via RBP-J promotes myeloid differentiation.

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12 December 2020

Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

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12 December 2020

Notch signaling: cell fate control and signal integration in development

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12 December 2020

Genes of the Enhancer of split and achaete-scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila.

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12 December 2020

Functional interaction between the mouse notch1 intracellular region and histone acetyltransferases PCAF and GCN5

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12 December 2020

Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor

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12 December 2020

Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1.

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12 December 2020

EBNA-2 upregulation of Epstein-Barr virus latency promoters and the cellular CD23 promoter utilizes a common targeting intermediate, CBF1.

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12 December 2020

Notch signaling is required for arterial-venous differentiation during embryonic vascular development.

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12 December 2020

Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling

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12 December 2020

Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines

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12 December 2020

Asymmetric Notch activation specifies photoreceptors R3 and R4 and planar polarity in the Drosophila eye.

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12 December 2020

The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis

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12 December 2020

The Notch ligand, Delta-1, inhibits the differentiation of monocytes into macrophages but permits their differentiation into dendritic cells.

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12 December 2020

Fringe modulates Notch-ligand interactions.

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12 December 2020

Notch signaling in leukemia

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12 December 2020

Notch-1 and Notch-2 exhibit unique patterns of expression in human B-lineage cells

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12 December 2020

Sequence of the notch locus of Drosophila melanogaster: relationship of the encoded protein to mammalian clotting and growth factors

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12 December 2020

Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.

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12 December 2020

A novel proteolytic cleavage involved in Notch signaling: the role of the disintegrin-metalloprotease TACE

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12 December 2020

Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development

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12 December 2020

Notch and presenilin: a proteolytic mechanism emerges

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12 December 2020

Proto-oncogene of int-3, a mouse Notch homologue, is expressed in endothelial cells during early embryogenesis.

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12 December 2020

Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kinetics

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12 December 2020

Mouse Jagged2 is differentially expressed in hematopoietic progenitors and endothelial cells and promotes the survival and proliferation of hematopoietic progenitors by direct cell-to-cell contact

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12 December 2020

A common enzyme connects notch signaling and Alzheimer's disease

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12 December 2020

Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta.

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12 December 2020

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

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12 December 2020

Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression

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12 December 2020

Functional domains of LAG-2, a putative signaling ligand for LIN-12 and GLP-1 receptors in Caenorhabditis elegans

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12 December 2020

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation

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12 December 2020

Transduction of Notch2 in feline leukemia virus-induced thymic lymphoma

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12 December 2020

The helix-loop-helix gene E2A is required for B cell formation

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12 December 2020

lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans.

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12 December 2020

Nuclear localization of CBF1 is regulated by interactions with the SMRT corepressor complex

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12 December 2020

Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor

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12 December 2020

A histone deacetylase corepressor complex regulates the Notch signal transduction pathway

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12 December 2020

Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.

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12 December 2020

GLP-1 is localized to the mitotic region of the C. elegans germ line

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12 December 2020

A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells

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12 December 2020

Human deltex is a conserved regulator of Notch signalling

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12 December 2020

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

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12 December 2020

Both E12 and E47 allow commitment to the B cell lineage

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12 December 2020

Groucho/TLE family proteins and transcriptional repression

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12 December 2020

Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila

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12 December 2020

A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis

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12 December 2020

Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

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12 December 2020

Hematopoiesis and angiogenesis.

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12 December 2020

Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors.

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12 December 2020

Suppression of erythroid but not megakaryocytic differentiation of human K562 erythroleukemic cells by notch-1.

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12 December 2020

Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins

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12 December 2020

LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway

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12 December 2020

The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1

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12 December 2020

Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision.

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12 December 2020

The N- and C-terminal regions of RBP-J interact with the ankyrin repeats of Notch1 RAMIC to activate transcription

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12 December 2020

Notch activity influences the alphabeta versus gammadelta T cell lineage decision

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12 December 2020

Structure/function studies of lin-12/Notch proteins.

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12 December 2020

The ins and outs of notch signaling

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12 December 2020

Vascular development: cellular and molecular regulation.

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12 December 2020

The bHLH gene Hes1 is essential for expansion of early T cell precursors

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12 December 2020

Cutting edge: protective effects of notch-1 on TCR-induced apoptosis.

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12 December 2020

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

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12 December 2020

numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos

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12 December 2020

wingless expression mediates determination of peripheral nervous system elements in late stages of Drosophila wing disc development.

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12 December 2020

Groucho proteins: transcriptional corepressors for specific subsets of DNA-binding transcription factors in vertebrates and invertebrates.

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12 December 2020

Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats

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12 December 2020

Genetic and molecular characterization of a Notch mutation in its Delta- and Serrate-binding domain in Drosophila.

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12 December 2020

Notch inhibition of E47 supports the existence of a novel signaling pathway

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12 December 2020

Regulation of T cell fate by Notch

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12 December 2020

Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats

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12 December 2020

The suppressor of hairless protein participates in notch receptor signaling

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12 December 2020

Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo

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12 December 2020

Pax5 determines the identity of B cells from the beginning to the end of B-lymphopoiesis

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12 December 2020

TLE, the Human Homolog of Groucho, Interacts with AML1 and Acts as a Repressor of AML1-Induced Transactivation

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12 December 2020

Delta-1 activation of notch-1 signaling results in HES-1 transactivation.

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12 December 2020

glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins

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12 December 2020

PEST sequences and regulation by proteolysis

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12 December 2020

The notch receptor and its ligands are selectively expressed during hematopoietic development in the mouse

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12 December 2020

Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells.

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12 December 2020

Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway.

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12 December 2020

The Notch ligand, X-Delta-2, mediates segmentation of the paraxial mesoderm in Xenopus embryos.

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12 December 2020

Notch signaling is essential for vascular morphogenesis in mice

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12 December 2020

Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans.

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12 December 2020

Notch receptors and hematopoiesis

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12 December 2020

A human homologue of the Drosophila developmental gene, Notch, is expressed in CD34+ hematopoietic precursors.

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12 December 2020

Notch signaling: Fringe really is a glycosyltransferase.

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12 December 2020

The Notch1 receptor is cleaved constitutively by a furin-like convertase

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12 December 2020

Mastermind is a putative activator for Notch.

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12 December 2020

The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain

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12 December 2020

Transcriptional repression by Pax5 (BSAP) through interaction with corepressors of the Groucho family

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12 December 2020

A ligand-induced extracellular cleavage regulates gamma-secretase-like proteolytic activation of Notch1

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12 December 2020

Embryonic lethality in mice homozygous for a processing-deficient allele of Notch1.

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12 December 2020

SKIP, a CBF1-associated protein, interacts with the ankyrin repeat domain of NotchIC To facilitate NotchIC function

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12 December 2020

Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.

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12 December 2020

Early thymocyte development is regulated by modulation of E2A protein activity

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12 December 2020

Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells.

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12 December 2020

The bHLH gene Hes1 regulates differentiation of multiple cell types

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12 December 2020

Notch1 is essential for postimplantation development in mice.

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12 December 2020

Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription

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12 December 2020

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

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12 December 2020

SEL-8, a nuclear protein required for LIN-12 and GLP-1 signaling in Caenorhabditis elegans

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12 December 2020

An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

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12 December 2020

Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development

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12 December 2020

Interaction between Wingless and Notch signaling pathways mediated by dishevelled.

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12 December 2020

The notch ligand jagged-1 represents a novel growth factor of human hematopoietic stem cells

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12 December 2020

Expression analysis of a Notch homologue in the mouse embryo.

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12 December 2020

Inhibition of granulocytic differentiation by mNotch1.

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12 December 2020

A role for hematopoietic stem cells in promoting angiogenesis

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12 December 2020

A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer

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12 December 2020

Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation.

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12 December 2020

Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice

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12 December 2020

Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes

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12 December 2020

Coming to grips with Notch

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12 December 2020

Distinct and regulated expression of Notch receptors in hematopoietic lineages and during myeloid differentiation

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12 December 2020

Identifiers

DOI

10.1007/BF02982106

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Dimensions Publication ID

4 August 2017

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