An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice (Q34723920)

4 August 2017

An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice (English)

1 reference

4 August 2017

15

Mark A Mintun

1 reference

4 August 2017

Randall J Bateman

13

0 references

John C. Morris

14

object named as

John C Morris

1 reference

4 August 2017

1

Yvette I Sheline

1 reference

4 August 2017

Kevin Yarasheski

3

1 reference

ORCID Public Data File 2021

Mateusz S Jasielec

5

object named as

Mateusz S Jasielec

1 reference

4 August 2017

4

Robert Swarm

1 reference

4 August 2017

Christine Frederiksen

10

object named as

Christine Frederiksen

1 reference

4 August 2017

11

Monica V Grzelak

1 reference

4 August 2017

17

John R Cirrito

1 reference

4 August 2017

Tim West

2

1 reference

4 August 2017

Jonathan R Fisher

6

1 reference

4 August 2017

Whitney D Ficker

7

1 reference

4 August 2017

Ping Yan

8

1 reference

4 August 2017

Chengjie Xiong

9

1 reference

4 August 2017

Robert Chott

12

1 reference

4 August 2017

Jin-Moo Lee

16

1 reference

4 August 2017

language of work or name

English

0 references

publication date

1 May 2014

1 reference

Science Translational Medicine

4 August 2017

1 reference

4 August 2017

6

1 reference

4 August 2017

236re4

1 reference

4 August 2017

236

1 reference

Monoamine neurocircuitry in depression and strategies for new treatments

4 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Depression and hippocampal neurogenesis: a road to remission?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Low-density lipoprotein receptor overexpression enhances the rate of brain-to-blood Aβ clearance in a mouse model of β-amyloidosis.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Serotonin signaling is associated with lower amyloid-β levels and plaques in transgenic mice and humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

The extracellular regulated kinase-1 (ERK1) controls regulated alpha-secretase-mediated processing, promoter transactivation, and mRNA levels of the cellular prion protein.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Neuronal activity regulates the regional vulnerability to amyloid-β deposition

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Alzheimer's disease: the challenge of the second century

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

A gamma-secretase inhibitor decreases amyloid-beta production in the central nervous system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Serum brain-derived neurotrophic factor, depression, and antidepressant medications: meta-analyses and implications

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Dose translation from animal to human studies revisited

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

ERK1/2 is an endogenous negative regulator of the gamma-secretase activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Depressed new neurons--adult hippocampal neurogenesis and a cellular plasticity hypothesis of major depression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Alzheimer Disease in the US Population

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Ras-dependent ERK activation by the human G(s)-coupled serotonin receptors 5-HT4(b) and 5-HT7(a).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Effect of a 5-HT(2C) serotonin agonist, dexnorfenfluramine, on amyloid precursor protein metabolism in guinea pigs.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Tangles and plaques in nondemented aging and "preclinical" Alzheimer's disease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Kinetic theory of fibrillogenesis of amyloid beta-protein

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Serotonin 5-HT2a and 5-HT2c receptors stimulate amyloid precursor protein ectodomain secretion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

5-Hydroxytryptamine (5-HT)4 receptors in post mortem human brain tissue: distribution, pharmacology and effects of neurodegenerative diseases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Clinical and biomarker changes in dominantly inherited Alzheimer's disease

7 July 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3008169

Changes of Biogenic Amines and Their Metabolites in Postmortem Brains from Patients with Alzheimer-Type Dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3008169

The human serotonin 5-HT4 receptor regulates secretion of non-amyloidogenic precursor protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3008169

Enhanced activation of Akt and extracellular-regulated kinase pathways by simultaneous occupancy of Gq-coupled 5-HT2A receptors and Gs-coupled 5-HT7A receptors in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3008169

Partial reduction of BACE1 has dramatic effects on Alzheimer plaque and synaptic pathology in APP Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3008169

Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3008169

Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3008169

A new look at the statistical model identification

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3008169

Small sample inference for fixed effects from restricted maximum likelihood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCITRANSLMED.3008169

In VivoAssessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269372

Activation of extracellular signal-regulated kinase (ERK) and Akt by human serotonin 5-HT(1B) receptors in transfected BE(2)-C neuroblastoma cells is inhibited by RGS4

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24828079

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCITRANSLMED.3008169

1 reference

release_q33zzv5uxjgetnbf6oxbh6vq3a

4 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/q33zzv5uxjgetnbf6oxbh6vq3a

mapped directly with Wikidata item

24 November 2022

based on heuristic

PMCID

4269372

1 reference

4 August 2017

1 reference