Probes for chemical genomics by design (Q34731398)

4 August 2017

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title

Probes for chemical genomics by design (English)

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4 August 2017

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Edward D Zanders

1

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PubMed ID

12110227

4 August 2017

David S Bailey

series ordinal

2

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PubMed ID

12110227

4 August 2017

Philip M Dean

series ordinal

3

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4 August 2017

1 July 2002

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4 August 2017

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4 August 2017

7

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4 August 2017

13

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4 August 2017

711-718

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Chemical genetics: ligand-based discovery of gene function

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Chemical genomics: what will it take and who gets to play?

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Drug discovery: a historical perspective

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

High-throughput chemistry and structure-based design: survival of the smartest

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Functional cell-based uHTS in chemical genomic drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

A gene expression database for the molecular pharmacology of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Functional discovery via a compendium of expression profiles

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

A chemical genomics approach toward understanding the global functions of the target of rapamycin protein (TOR).

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Small molecule developmental screens reveal the logic and timing of vertebrate development

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Target-oriented and diversity-oriented organic synthesis in drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Global Efforts in Structural Genomics

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

MODBASE, a database of annotated comparative protein structure models.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

The PROSITE database, its status in 2002

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

From structure to function: approaches and limitations

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Databases for protein-ligand complexes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Automated site-directed drug design: a general algorithm for knowledge acquisition about hydrogen-bonding regions at protein surfaces.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Computational tools for structure-based ligand design

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

CONCERTS: dynamic connection of fragments as an approach to de novo ligand design

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

GroupBuild: a fragment-based method for de novo drug design

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Structure-based drug design: the discovery of novel nonpeptide orally active inhibitors of human renin

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Development of a pharmacophore model for histamine H3 receptor antagonists, using the newly developed molecular modeling program SLATE.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

SLATE: a method for the superposition of flexible ligands.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Initial sequencing and analysis of the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

The commercial use of structural genomics.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

Completeness in structural genomics.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902325-5

7 January 2021

10.1016/S1359-6446(02)02325-5

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12110227