Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice (Q34737496)

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21 February 2020

title

Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice (English)

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21 February 2020

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13

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21 February 2020

5

Elaine R Mardis

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21 February 2020

author name string

Elise Peterson Lu

1

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21 February 2020

Michael McLellan

2

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21 February 2020

Li Ding

3

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21 February 2020

Robert Fulton

4

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21 February 2020

Richard K Wilson

6

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21 February 2020

Christopher A Miller

7

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21 February 2020

Peter Westervelt

8

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21 February 2020

John F DiPersio

9

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21 February 2020

Daniel C Link

10

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21 February 2020

Matthew J Walter

11

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21 February 2020

Timothy J Ley

12

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21 February 2020

language of work or name

English

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publication date

27 October 2014

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21 February 2020

number of pages

9

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based on heuristic

inferred from page(s)

published in

Blood

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21 February 2020

volume

124

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21 February 2020

issue

26

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21 February 2020

page(s)

3887-3895

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The DNA double-strand break response is abnormal in myeloblasts from patients with therapy-related acute myeloid leukemia.

21 February 2020

cites work

1 reference

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7 July 2018

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7 July 2018

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Mutational analysis of therapy-related myelodysplastic syndromes and acute myelogenous leukemia

7 July 2018

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DNA damage and repair in human cancer: molecular mechanisms and contribution to therapy-related leukemias.

7 July 2018

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DNA damage checkpoints in stem cells, ageing and cancer.

7 July 2018

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Genetic susceptibility to therapy-related leukemia after Hodgkin lymphoma or non-Hodgkin lymphoma: role of drug metabolism, apoptosis and DNA repair

7 July 2018

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The origin and evolution of mutations in acute myeloid leukemia

7 July 2018

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Roles of p53 in various biological aspects of hematopoietic stem cells

7 July 2018

1 reference

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Clonal architecture of secondary acute myeloid leukemia

7 July 2018

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A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage

7 July 2018

1 reference

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7 July 2018

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Altered hematopoietic cell gene expression precedes development of therapy-related myelodysplasia/acute myeloid leukemia and identifies patients at risk

7 July 2018

1 reference

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The ups and downs of p53 regulation in hematopoietic stem cells

7 July 2018

1 reference

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The p53 tumor suppressor protein regulates hematopoietic stem cell fate

7 July 2018

1 reference

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Regulation of cell differentiation by the DNA damage response

7 July 2018

1 reference

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VarScan: variant detection in massively parallel sequencing of individual and pooled samples

7 July 2018

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Fast and accurate short read alignment with Burrows-Wheeler transform

7 July 2018

1 reference

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Genetic variation in caspase genes and risk of non-Hodgkin lymphoma: a pooled analysis of 3 population-based case-control studies

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4271179

Accelerated telomere shortening precedes development of therapy-related myelodysplasia or acute myelogenous leukemia after autologous transplantation for lymphoma

7 July 2018

1 reference

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Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia

7 July 2018

1 reference

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DNA repair is crucial for maintaining hematopoietic stem cell function

7 July 2018

1 reference

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Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

7 July 2018

1 reference

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DNA repair is limiting for haematopoietic stem cells during ageing

7 July 2018

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Advances in the understanding of susceptibility to treatment-related acute myeloid leukaemia

7 July 2018

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DNA repair defects in stem cell function and aging

7 July 2018

1 reference

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The role of apoptosis in regulating hematopoiesis and hematopoietic stem cells

7 July 2018

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Adult Apaf-1-deficient mice exhibit male infertility

7 July 2018

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

7 July 2018

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DNA-damage-induced differentiation in hematopoietic stem cells.

7 July 2018

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A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal.

26 October 2018

1 reference

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Identification of candidate alkylator-induced cancer susceptibility genes by whole genome scanning in mice.

26 October 2018

1 reference

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Caspase 9 promoter polymorphisms and risk of primary lung cancer.

26 October 2018

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Stringent regulation of DNA repair during human hematopoietic differentiation: a gene expression and functional analysis.

26 October 2018

1 reference

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10.1182/BLOOD-2014-06-582551

26 October 2018

Identifiers

DOI

1 reference

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21 February 2020

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21 February 2020

PubMed publication ID

25349173

1 reference