Pancreatic islet xenograft survival in mice is extended by a combination of alpha-1-antitrypsin and single-dose anti-CD4/CD8 therapy (Q34744307)

4 August 2017

Pancreatic islet xenograft survival in mice is extended by a combination of alpha-1-antitrypsin and single-dose anti-CD4/CD8 therapy (English)

1 reference

4 August 2017

1 reference

Efrat Ashkenazi

1

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4 August 2017

Boris M Baranovski

series ordinal

2

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4 August 2017

Galit Shahaf

series ordinal

3

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4 August 2017

Eli C Lewis

series ordinal

4

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4 August 2017

language of work or name

English

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publication date

22 May 2013

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4 August 2017

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4 August 2017

8

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4 August 2017

5

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4 August 2017

e63625

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Creative Commons Attribution 4.0 International

4 August 2017

start time

22 May 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

α-1-antitrypsin gene delivery reduces inflammation, increases T-regulatory cell population size and prevents islet allograft rejection

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α 1-antitrypsin enhances insulin secretion and prevents cytokine-mediated apoptosis in pancreatic β-cells

7 July 2018

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α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8

7 July 2018

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7 July 2018

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Culture of impure human islet fractions in the presence of alpha-1 antitrypsin prevents insulin cleavage and improves islet recovery

7 July 2018

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Anti-CD154 mAb and rapamycin induce T regulatory cell mediated tolerance in rat-to-mouse islet transplantation

7 July 2018

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Short-term administrations of a combination of anti-LFA-1 and anti-CD154 monoclonal antibodies induce tolerance to neonatal porcine islet xenografts in mice

7 July 2018

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Improving islet transplantation: a road map for a widespread application for the cure of persons with type I diabetes

7 July 2018

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Pig embryonic pancreatic tissue as a source for transplantation in diabetes: transient treatment with anti-LFA1, anti-CD48, and FTY720 enables long-term graft maintenance in mice with only mild ongoing immunosuppression

7 July 2018

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IL-1beta receptor blockade protects islets against pro-inflammatory cytokine induced necrosis and apoptosis

7 July 2018

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7 July 2018

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alpha1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice

7 July 2018

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Xenotransplantation: where are we in 2008?

7 July 2018

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Aralast: an alpha 1-protease inhibitor for the treatment of alpha-antitrypsin deficiency

7 July 2018

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Rapid loss of intraportally transplanted islets: an overview of pathophysiology and preventive strategies.

7 July 2018

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Immune mechanisms associated with the rejection of encapsulated neonatal porcine islet xenografts.

7 July 2018

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7 July 2018

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Alpha1-antitrypsin monotherapy prolongs islet allograft survival in mice

7 July 2018

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Inflammation-mediated dysfunction and apoptosis in pancreatic islet transplantation: implications for intrahepatic grafts

7 July 2018

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Inflammatory mediators expressed in human islets of Langerhans: implications for islet transplantation

7 July 2018

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IL-1 produced and released endogenously within human islets inhibits beta cell function

7 July 2018

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Xenograft rejection of porcine islet-like cell clusters in normal and natural killer cell-depleted mice

7 July 2018

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Involvement of interleukin 1 and interleukin 1 antagonist in pancreatic beta-cell destruction in insulin-dependent diabetes mellitus

7 July 2018

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Antiinflammatory properties of hepatic acute phase proteins: preferential induction of interleukin 1 (IL-1) receptor antagonist over IL-1 beta synthesis by human peripheral blood mononuclear cells

7 July 2018

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ATG-induced expression of FOXP3 in human CD4(+) T cells in vitro is associated with T-cell activation and not the induction of FOXP3(+) T regulatory cells.

7 July 2018

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Combination of anti-CD4 with anti-LFA-1 and anti-CD154 monoclonal antibodies promotes long-term survival and function of neonatal porcine islet xenografts in spontaneously diabetic NOD mice.

21 January 2018

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IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.

21 January 2018

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Recombinant adeno-associated virus-mediated alpha-1 antitrypsin gene therapy prevents type I diabetes in NOD mice

21 January 2018

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Alpha1-antitrypsin inhibits Moraxella catarrhalis MID protein-induced tonsillar B cell proliferation and IL-6 release

21 January 2018

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Alpha-1 antitrypsin up-regulates human B cell differentiation selectively into IgE- and IgG4- secreting cells.

21 January 2018

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Pulmonary epithelial expression of human alpha1-antitrypsin in transgenic mice results in delivery of alpha1-antitrypsin protein to the interstitium

21 January 2018

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Interleukin-1 receptor antagonist enhances islet engraftment without impacting serum levels of nitrite or osteopontin.

21 January 2018

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Role of donor-derived monocyte chemoattractant protein-1 in murine islet transplantation.

21 January 2018

1 reference

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Anti-CD25 mAb, anti-IL2 mAb, and IL2 block tolerance induction through anti-CD154 mAb and rapamycin in xenogeneic islet transplantation

21 January 2018

1 reference

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Protective effect of heme oxygenase-1 to pancreas islet xenograft

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0063625

Tracing of islet graft survival by way of in vivo fluorescence imaging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0063625

Simultaneous blockade of co-stimulatory signals, CD28 and ICOS, induced a stable tolerance in rat heart transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0063625

Revascularization of pancreatic islet allografts is enhanced by α-1-antitrypsin under anti-inflammatory conditions.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661573

Rapamycin impairs proliferation of transplanted islet β cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3661573

Embryonic pig pancreatic tissue for the treatment of diabetes: potential role of immune suppression with "off-the-shelf" third-party regulatory T cells

26 October 2018

1 reference

12 December 2020

Sustained expression of circulating human alpha-1 antitrypsin reduces inflammation, increases CD4+FoxP3+ Treg cell population and prevents signs of experimental autoimmune encephalomyelitis in mice

1 reference

12 December 2020

CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen

1 reference

12 December 2020

The degree of phylogenetic disparity of islet grafts dictates the reliance on indirect CD4 T-cell antigen recognition for rejection

1 reference

12 December 2020

Prolonged survival of fetal pig islet xenografts in mice lacking the capacity for an indirect response

1 reference

12 December 2020

NK cells, macrophages, and humoral immune responses are dominant in primary nonfunction of islet grafts in the dog-to-rat xenotransplant model

1 reference

12 December 2020

WITHDRAWN: Potential link between alpha 1 anti-trypsin and PAR-2 in the prevention of beta cell dysfunction(☆)

1 reference

3 January 2024

https://opencitations.net/index/api/v1/citations/10.1016/J.MCE.2011.08.040

Identifiers

DOI

10.1371/JOURNAL.PONE.0063625

1 reference

4 August 2017

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1 reference

4 August 2017

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