Adiponectin inhibits osteoclastogenesis and bone resorption via APPL1-mediated suppression of Akt1. (Q34752434)

4 August 2017

Adiponectin inhibits osteoclastogenesis and bone resorption via APPL1-mediated suppression of Akt1. (English)

1 reference

4 August 2017

Qisheng Tu

1

1 reference

4 August 2017

Jin Zhang

2

1 reference

4 August 2017

Lily Q Dong

3

1 reference

4 August 2017

Eileen Saunders

4

1 reference

4 August 2017

En Luo

5

1 reference

4 August 2017

Jean Tang

6

1 reference

4 August 2017

Jake Chen

7

1 reference

4 August 2017

language of work or name

English

0 references

publication date

7 February 2011

1 reference

Journal of Biological Chemistry

4 August 2017

1 reference

4 August 2017

286

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4 August 2017

12542-12553

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4 August 2017

14

1 reference

Baseline serum total adiponectin level is positively associated with changes in bone mineral density after 1-year treatment of type 2 diabetes mellitus

4 August 2017

1 reference

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The role of body mass index, insulin, and adiponectin in the relation between fat distribution and bone mineral density

7 July 2018

1 reference

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The relationship between adipokines, body composition, and bone density in men with chronic obstructive pulmonary disease

7 July 2018

1 reference

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Adiponectin stimulates osteoblast differentiation through induction of COX2 in mesenchymal progenitor cells

7 July 2018

1 reference

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Sex differences in the association between adiponectin and BMD, bone loss, and fractures: the Rancho Bernardo study

7 July 2018

1 reference

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In vitro and in vivo effects of adiponectin on bone

7 July 2018

1 reference

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Adiponectin is a negative regulator of bone mineral and bone strength in growing mice

7 July 2018

1 reference

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Inhibition of Hsp90 activates osteoclast c-Src signaling and promotes growth of prostate carcinoma cells in bone

7 July 2018

1 reference

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Targeted overexpression of BSP in osteoclasts promotes bone metastasis of breast cancer cells

7 July 2018

1 reference

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Overexpression of bone sialoprotein leads to an uncoupling of bone formation and bone resorption in mice

7 July 2018

1 reference

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High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate-activated protein kinase

7 July 2018

1 reference

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Systemically transplanted bone marrow stromal cells contributing to bone tissue regeneration

7 July 2018

1 reference

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Cross-susceptibility between periodontal disease and type 2 diabetes mellitus: an immunobiological perspective.

7 July 2018

1 reference

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AKT/PKB signaling: navigating downstream

7 July 2018

1 reference

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1 reference

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Relationship of obesity with osteoporosis

7 July 2018

1 reference

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Adiponectin inhibits osteoclast formation stimulated by lipopolysaccharide from Actinobacillus actinomycetemcomitans

7 July 2018

1 reference

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APPL1 binds to adiponectin receptors and mediates adiponectin signalling and function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069456

Relation of body composition, fat mass, and serum lipids to osteoporotic fractures and bone mineral density in Chinese men and women

7 July 2018

1 reference

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Diosgenin inhibits osteoclastogenesis, invasion, and proliferation through the downregulation of Akt, I kappa B kinase activation and NF-kappa B-regulated gene expression

7 July 2018

1 reference

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Bone and body composition of children and adolescents with repeated forearm fractures

7 July 2018

1 reference

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BSP and RANKL induce osteoclastogenesis and bone resorption synergistically

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3069456

Adipose tissue, adipokines, and inflammation

7 July 2018

1 reference

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Leptin regulation of bone resorption by the sympathetic nervous system and CART

7 July 2018

1 reference

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Adiponectin differentially regulates cytokines in porcine macrophages

7 July 2018

1 reference

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Structure, regulation and function of PKB/AKT--a major therapeutic target

7 July 2018

1 reference

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Autoregulation of bone sialoprotein gene in pre-osteoblastic and non-osteoblastic cells

7 July 2018

1 reference

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Amylin inhibits bone resorption while the calcitonin receptor controls bone formation in vivo

7 July 2018

1 reference

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The calcineurin/nuclear factor of activated T cells signaling pathway regulates osteoclastogenesis in RAW264.7 cells

7 July 2018

1 reference

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

7 July 2018

1 reference

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Obesity is associated with macrophage accumulation in adipose tissue

7 July 2018

1 reference

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Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

7 July 2018

1 reference

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Protein kinase B alpha/Akt1 regulates placental development and fetal growth

7 July 2018

1 reference

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GSK-3: tricks of the trade for a multi-tasking kinase

7 July 2018

1 reference

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Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

7 July 2018

1 reference

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Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

7 July 2018

1 reference

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Regulation of nuclear localization during signaling

7 July 2018

1 reference

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7 July 2018

1 reference

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Increased adipose tissue in male and female estrogen receptor-alpha knockout mice

7 July 2018

1 reference

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Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages

7 July 2018

1 reference

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Direct three-dimensional morphometric analysis of human cancellous bone: microstructural data from spine, femur, iliac crest, and calcaneus.

7 July 2018

1 reference

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7 July 2018

1 reference

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7 July 2018

1 reference

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AdipoQ is a novel adipose-specific gene dysregulated in obesity

7 July 2018

1 reference

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Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152405

Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.152405

Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.

21 January 2018

1 reference

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PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein

21 January 2018

1 reference

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Adiponectin as a novel determinant of bone mineral density and visceral fat.

21 January 2018

1 reference

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The relationship between serum resistin, leptin, adiponectin, ghrelin levels and bone mineral density in middle-aged men.

21 January 2018

1 reference

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Direct action of 1,25-dihydroxyvitamin D on bone: VDRKO bone shows excessive bone formation in normal mineral condition

21 January 2018

1 reference

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Haploinsufficiency of Runx2 results in bone formation decrease and different BSP expression pattern changes in two transgenic mouse models

21 January 2018

1 reference

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Akt1/Akt2 and mammalian target of rapamycin/Bim play critical roles in osteoclast differentiation and survival, respectively, whereas Akt is dispensable for cell survival in isolated osteoclast precursors

21 January 2018

1 reference

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Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice

21 January 2018

1 reference

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Hyperinsulinemia and bone mineral density in an elderly population: The Rotterdam study

21 January 2018

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Low Body Mass Index Is an Important Risk Factor for Low Bone Mass and Increased Bone Loss in Early Postmenopausal Women

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Obesity in the new millennium

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Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast

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Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways

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Role of collagen enzymatic and glycation induced cross-links as a determinant of bone quality in spontaneously diabetic WBN/Kob rats

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Adiponectin stimulates RANKL and inhibits OPG expression in human osteoblasts through the MAPK signaling pathway

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Identifiers

DOI

10.1074/JBC.M110.152405

1 reference

release_huwe6a7b7nh3zmfl4m6i2bjx6e

4 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/huwe6a7b7nh3zmfl4m6i2bjx6e

24 November 2022

mapped directly with Wikidata item

PMCID

3069456

1 reference

4 August 2017

1 reference