2-phenylethynesulfonamide Prevents Induction of Pro-inflammatory Factors and Attenuates LPS-induced Liver Injury by Targeting NHE1-Hsp70 Complex in Mice (Q34785717)

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English	2-phenylethynesulfonamide Prevents Induction of Pro-inflammatory Factors and Attenuates LPS-induced Liver Injury by Targeting NHE1-Hsp70 Complex in Mice	scientific article

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

2-phenylethynesulfonamide Prevents Induction of Pro-inflammatory Factors and Attenuates LPS-induced Liver Injury by Targeting NHE1-Hsp70 Complex in Mice (English)

1 reference

Europe PubMed Central

4 August 2017

author name string

Chao Huang

1

1 reference

Europe PubMed Central

4 August 2017

Jia Wang

2

1 reference

Europe PubMed Central

4 August 2017

Zhuo Chen

3

1 reference

Europe PubMed Central

4 August 2017

Yuzhe Wang

4

1 reference

Europe PubMed Central

4 August 2017

Wei Zhang

5

1 reference

Europe PubMed Central

4 August 2017

language of work or name

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publication date

21 June 2013

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Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

8

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Europe PubMed Central

4 August 2017

6

1 reference

Europe PubMed Central

4 August 2017

e67582

1 reference

Europe PubMed Central

4 August 2017

copyright license

Creative Commons Attribution 4.0 International

21 June 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

SKF83959, an agonist of phosphatidylinositol-linked D(1)-like receptors, promotes ERK1/2 activation and cell migration in cultured rat astrocytes

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Antileukemic activity of the HSP70 inhibitor pifithrin-μ in acute leukemia

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8 July 2018

Toll-like receptor 4-dependent Kupffer cell activation and liver injury in a novel mouse model of parenteral nutrition and intestinal injury

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8 July 2018

Inhibition of heat shock protein (molecular weight 90 kDa) attenuates proinflammatory cytokines and prevents lipopolysaccharide-induced liver injury in mice.

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8 July 2018

Obligatory role of heat shock protein 90 in iNOS induction

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8 July 2018

Activation of microglia depends on Na+/H+ exchange-mediated H+ homeostasis

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8 July 2018

The role of intestinal endotoxin in liver injury: a long and evolving history

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8 July 2018

Hsp70 ATPase Modulators as Therapeutics for Alzheimer's and other Neurodegenerative Diseases

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8 July 2018

A small molecule inhibitor of inducible heat shock protein 70.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689707

8 July 2018

Clinical correlation of circulating heat shock protein 70 in acute leukemia

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8 July 2018

Heat shock protein 70 (HSP70) induces cytotoxicity of T-helper cells

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8 July 2018

The BAG proteins: a ubiquitous family of chaperone regulators

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8 July 2018

Signaling to NF-kappaB by Toll-like receptors

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8 July 2018

Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689707

8 July 2018

The inhibition of LPS-induced production of inflammatory cytokines by HSP70 involves inactivation of the NF-kappaB pathway but not the MAPK pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689707

8 July 2018

Geldanamycin interferes with the 90-kDa heat shock protein, affecting lipopolysaccharide-mediated interleukin-1 expression and apoptosis within macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689707

8 July 2018

The role of intracellular Ca2+ in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes

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8 July 2018

Hsp70 chaperones: cellular functions and molecular mechanism

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689707

8 July 2018

The effect of lipopolysaccharide on cholecystokinin in murine plasma and tissue

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8 July 2018

Heat-shock protein 70 and heat-shock protein 90 associate with Toll-like receptor 4 in response to bacterial lipopolysaccharide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689707

8 July 2018

Hsp70 promotes TNF-mediated apoptosis by binding IKK gamma and impairing NF-kappa B survival signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689707

8 July 2018

NEMO trimerizes through its coiled-coil C-terminal domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689707

8 July 2018

The ATPase domain of hsp70 possesses a unique binding specificity for 3'-sulfogalactolipids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689707

8 July 2018

Negative regulation of the Apaf-1 apoptosome by Hsp70

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689707

8 July 2018

Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3689707

8 July 2018

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

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8 July 2018

Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium

1 reference

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8 July 2018

I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding

1 reference

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8 July 2018

The carboxyl-terminal region of the Na+/H+ exchanger interacts with mammalian heat shock protein.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0067582

21 January 2018

Novel anti-inflammatory effects of doxazosin in rodent models of inflammation.

1 reference

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Novel functional interaction between Na+/H+ exchanger 1 and tyrosine phosphatase SHP-2.

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26 October 2018

PHAPI, CAS, and Hsp70 promote apoptosome formation by preventing Apaf-1 aggregation and enhancing nucleotide exchange on Apaf-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/23805318

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Lipopolysaccharide and D-galactosamine-induced hepatic injury is mediated by TNF-alpha and not by Fas ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/23805318

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inferred from PubMed ID database lookup

BAG-1: a multi-functional pro-survival molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/23805318

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based on heuristic

inferred from PubMed ID database lookup

Caerulein-induced NF-kappaB/Rel activation requires both Ca2+ and protein kinase C as messengers

1 reference

https://pubmed.ncbi.nlm.nih.gov/23805318

12 December 2020

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Lung and liver injury following hepatic ischemia/reperfusion in the rat is increased by exogenous lipopolysaccharide which also increases hepatic TNF production in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/23805318

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based on heuristic

inferred from PubMed ID database lookup

Heat-shock protein 70 favours human liver recovery from ischaemia-reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/23805318

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based on heuristic

inferred from PubMed ID database lookup

Na(+)-H+ exchange in resident alveolar macrophages: activation by osmotic cell shrinkage

1 reference

https://pubmed.ncbi.nlm.nih.gov/23805318

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inferred from PubMed ID database lookup

Control of cytoplasmic pH by Na+/H+ exchange in rat peritoneal macrophages activated with phorbol ester

1 reference

https://pubmed.ncbi.nlm.nih.gov/23805318

12 December 2020

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Identifiers

10.1371/JOURNAL.PONE.0067582

1 reference

Europe PubMed Central

4 August 2017

2013PLoSO...867582H

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1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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