Allergy immunotherapy and inhibition of Th2 immune responses: a sufficient strategy? (Q34786974)

4 August 2017

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title

Allergy immunotherapy and inhibition of Th2 immune responses: a sufficient strategy? (English)

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4 August 2017

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David B Lewis

1

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4 August 2017

1 October 2002

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Current Opinion in Immunology

4 August 2017

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4 August 2017

14

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4 August 2017

644-651

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4 August 2017

5

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Enforced expression of GATA-3 in transgenic mice inhibits Th1 differentiation and induces the formation of a T1/ST2-expressing Th2-committed T cell compartment in vivo.

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Development of spontaneous airway changes consistent with human asthma in mice lacking T-bet

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

1 reference

7 January 2021

Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

A restricted subset of dendritic cells captures airborne antigens and remains able to activate specific T cells long after antigen exposure

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

IL-12/IL-13 axis in allergic asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Development of new IgE specificities to allergenic components in birch pollen extract during specific immunotherapy studied with immunoblotting and Pharmacia CAP System

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Different methods of local allergen-specific immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Immunological tolerance to inhaled antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Oral tolerance induction in dermatophagoides pteronyssinus-sensitized mice induces inhibition of IgE response and upregulation of TGF-beta secretion

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Pulmonary dendritic cells producing IL-10 mediate tolerance induced by respiratory exposure to antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Comparison of inflammatory responses to genetically engineered hypoallergenic derivatives of the major birch pollen allergen Bet v 1 and to recombinant Bet v 1 wild type in skin chamber fluids collected from birch pollen–allergic patients

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Role of IL-10 in allergen-specific immunotherapy and normal response to allergens

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Specific immunotherapy prevents increased levels of allergen-specific IL-4- and IL-13-producing cells during pollen season

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Oligoclonal analysis of the atopic T cell response to the group 1 allergen of Cynodon dactylon (bermuda grass) pollen: pre- and post-allergen-specific immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Interleukin-10 levels increase in cutaneous biopsies of patients undergoing wasp venom immunotherapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Grass pollen immunotherapy decreases the number of mast cells in the skin.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Grass pollen immunotherapy inhibits seasonal increases in basophils and eosinophils in the nasal epithelium.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Grass pollen immunotherapy: symptomatic improvement correlates with reductions in eosinophils and IL-5 mRNA expression in the nasal mucosa during the pollen season.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Sensitisation, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Allergen-derived long peptide immunotherapy down-regulates specific IgE response and protects from anaphylaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Inducing tolerance by intranasal administration of long peptides in naive and primed CBA/J mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Inhibition of mucosal and systemic T(h)2-type immune responses by intranasal peptides containing a dominant T cell epitope of the allergen Der p 1

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Peptide-mediated immune responses in specific immunotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Late asthmatic reactions provoked by intradermal injection of T-cell peptide epitopes are not associated with bronchial mucosal infiltration of eosinophils or T(H)2-type cells or with elevated concentrations of histamine or eicosanoids in bronchoalv

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Allergen-derived T cell peptide-induced late asthmatic reactions precede the induction of antigen-specific hyporesponsiveness in atopic allergic asthmatic subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Unique and shared IgE epitopes of Hev b 1 and Hev b 3 in latex allergy

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Induction of a non-encephalitogenic type 2 T helper-cell autoimmune responsein multiple sclerosis after administration of an altered peptide ligand ina placebo-controlled, randomized phase II trial

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

An unexpected version of horror autotoxicus: anaphylactic shock to a self-peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Modulation of Th2 responses by peptide analogues in a murine model of allergic asthma: amelioration or deterioration of the disease process depends on the Th1 or Th2 skewing characteristics of the therapeutic peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Threshold signaling of human Th0 cells in activation and anergy: modulation of effector function by altered TCR ligand.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Distinct human T cell repertoires mediate immediate and delayed-type hypersensitivity to the Trichophyton antigen, Tri r 2.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Control of intestinal inflammation by regulatory T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Role of CD4(+) CD25(+) regulatory T cells in T helper 2 cell-mediated allergic inflammation in the airways

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Activation of CD25(+)CD4(+) regulatory T cells by oral antigen administration

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Differentiation of T regulatory cells by immature dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Characterization of a new subpopulation of mouse CD8alpha+ B220+ dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

T regulatory cells 1 inhibit a Th2-specific response in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Interleukin-10 and the interleukin-10 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Uncoupling of inflammatory chemokine receptors by IL-10: generation of functional decoys

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

IL-10 is necessary for the expression of airway hyperresponsiveness but not pulmonary inflammation after allergic sensitization

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

IL-10 reduces Th2 cytokine production and eosinophilia but augments airway reactivity in allergic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

IL-10 gene knockout attenuates allergen-induced airway hyperresponsiveness in C57BL/6 mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

IL-10 deficiency prevents IL-5 overproduction and eosinophilic inflammation in a murine model of asthma-like reaction

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Blockade of transforming growth factor beta/Smad signaling in T cells by overexpression of Smad7 enhances antigen-induced airway inflammation and airway reactivity

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

CD4(+) T helper cells engineered to produce latent TGF-beta1 reverse allergen-induced airway hyperreactivity and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Experimental approaches to analysis of immune dysregulation in human allergic disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Regulatory T cells and allergic asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Differential effects of endogenous and exogenous interferon-gamma on immunoglobulin E, cellular infiltration, and airway responsiveness in a murine model of allergic asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Mechanisms preventing allergen-induced airways hyperreactivity: role of tolerance and immune deviation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Respiratory infection with influenza A virus interferes with the induction of tolerance to aeroallergens

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Is asthma really due to a polarized T cell response toward a helper T cell type 2 phenotype?

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Could asthma be worsened by stimulating the T-helper type 1 immune response?

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Interleukin 12 p40 production by barrier epithelial cells during airway inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Effects of recombinant human interleukin-12 on eosinophils, airway hyper-responsiveness, and the late asthmatic response

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Airway hyperresponsiveness, late allergic response, and eosinophilia are reversed with mycobacterial antigens in ovalbumin-presensitized mice

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Intradermal administration of a killed Mycobacterium vaccae suspension (SRL 172) is associated with improvement in atopic dermatitis in children with moderate-to-severe disease

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

The effect of delipidated deglycolipidated (DDMV) and heat-killed Mycobacterium vaccae in asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Delayed hypersensitivity to tuberculin, total immunoglobulin E, specific sensitization, and atopic manifestation in longitudinally followed early Bacille Calmette-Guérin-vaccinated and nonvaccinated children

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Suppression of airway eosinophilia by killed Mycobacterium vaccae-induced allergen-specific regulatory T-cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

DNA-based immunotherapeutics for the treatment of allergic disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

A Toll-like receptor recognizes bacterial DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

CpG oligodeoxynucleotides can reverse Th2-associated allergic airway responses and alter the B7.1/B7.2 expression in a murine model of asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Conjugation of immunostimulatory DNA to the short ragweed allergen amb a 1 enhances its immunogenicity and reduces its allergenicity

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Novel roles of CpG oligodeoxynucleotides as a leader for the sampling and presentation of CpG-tagged antigen by dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Systemic administration of immunostimulatory DNA sequences mediates reversible inhibition of Th2 responses in a mouse model of asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

ICOS is critical for T helper cell-mediated lung mucosal inflammatory responses

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

ICOS co-stimulatory receptor is essential for T-cell activation and function

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Treatment of childhood asthma with anti-immunoglobulin E antibody (omalizumab).

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Effect of omalizumab on symptoms of seasonal allergic rhinitis: a randomized controlled trial.

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Efficacy of soluble IL-4 receptor for the treatment of adults with asthma

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

IL-13 induces airways hyperreactivity independently of the IL-4R alpha chain in the allergic lung

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

Local blockade of allergic airway hyperreactivity and inflammation by the poxvirus-derived pan-CC-chemokine inhibitor vCCI

1 reference

https://api.crossref.org/works/10.1016%2FS0952-7915%2802%2900388-6

7 January 2021

10.1016/S0952-7915(02)00388-6

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12183167