Agnostic about in vivo inverse agonism of agouti-related peptide (Q34788441)

4 August 2017

title

Agnostic about in vivo inverse agonism of agouti-related peptide (English)

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4 August 2017

Malcolm J Low

1

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4 August 2017

language of work or name

English

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publication date

1 May 2011

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4 August 2017

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4 August 2017

volume

152

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4 August 2017

issue

5

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4 August 2017

page(s)

1731-1733

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Loss of agouti-related peptide does not significantly impact the phenotype of murine POMC deficiency

4 August 2017

cites work

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8 July 2018

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8 July 2018

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The evasive nature of drug efficacy: implications for drug discovery

8 July 2018

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Humanized MC1R transgenic mice reveal human specific receptor function.

8 July 2018

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Modulating G-protein-coupled receptors: from traditional pharmacology to allosterics

8 July 2018

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Inverse agonism: from curiosity to accepted dogma, but is it clinically relevant?

8 July 2018

1 reference

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The natural inverse agonist agouti-related protein induces arrestin-mediated endocytosis of melanocortin-3 and -4 receptors

8 July 2018

1 reference

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Preservation of eumelanin hair pigmentation in proopiomelanocortin-deficient mice on a nonagouti (a/a) genetic background

8 July 2018

1 reference

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Constitutive activity of the melanocortin-4 receptor is maintained by its N-terminal domain and plays a role in energy homeostasis in humans

8 July 2018

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8 July 2018

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AgRP(83-132) acts as an inverse agonist on the human-melanocortin-4 receptor

8 July 2018

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Overexpression of Agrt leads to obesity in transgenic mice.

8 July 2018

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Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein

8 July 2018

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Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.

8 July 2018

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Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

8 July 2018

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Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.

8 July 2018

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Interactions of alpha-melanotropin and agouti on B16 melanoma cells: evidence for inverse agonism of agouti

26 October 2018

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12 December 2020

Constitutive receptor activity series: endogenous inverse agonists and constitutive receptor activity in the melanocortin system

1 reference

12 December 2020

Molecular basis of melanocortin-4 receptor for AGRP inverse agonism

1 reference

12 December 2020

In vivo evidence for inverse agonism of Agouti-related peptide in the central nervous system of proopiomelanocortin-deficient mice

1 reference

12 December 2020

Identifiers

DOI

10.1210/EN.2011-0232

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4 August 2017

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4 August 2017

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