Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist (Q34789625)

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16 January 2020

title

Identification of SR3335 (ML-176): a synthetic RORα selective inverse agonist (English)

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16 January 2020

11

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16 January 2020

author name string

Naresh Kumar

1

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16 January 2020

Douglas J Kojetin

2

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16 January 2020

Laura A Solt

3

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16 January 2020

K Ganesh Kumar

4

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16 January 2020

Philippe Nuhant

5

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16 January 2020

Derek R Duckett

6

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16 January 2020

Michael D Cameron

7

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16 January 2020

Andrew A Butler

8

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16 January 2020

William R Roush

9

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16 January 2020

Patrick R Griffin

10

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16 January 2020

publication date

6 December 2010

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16 January 2020

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16 January 2020

volume

6

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16 January 2020

issue

3

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16 January 2020

page(s)

218-222

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Identification of SR1078, a synthetic agonist for the orphan nuclear receptors RORα and RORγ.

16 January 2020

cites work

1 reference

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Ligand regulation of retinoic acid receptor-related orphan receptors: implications for development of novel therapeutics

8 July 2018

1 reference

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Regulation of adipogenesis by natural and synthetic REV-ERB ligands.

8 July 2018

1 reference

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Regulation of FGF21 expression and secretion by retinoic acid receptor-related orphan receptor alpha.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076127

A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol)

8 July 2018

1 reference

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Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma

8 July 2018

1 reference

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Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands

8 July 2018

1 reference

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The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist.

8 July 2018

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8 July 2018

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Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease

8 July 2018

1 reference

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Identification of heme as the ligand for the orphan nuclear receptors REV-ERBalpha and REV-ERBbeta

8 July 2018

1 reference

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8 July 2018

The pharmacology of LXR.

1 reference

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Crystal structure of the human RORalpha Ligand binding domain in complex with cholesterol sulfate at 2.2 A

8 July 2018

1 reference

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X-ray structure of the hRORalpha LBD at 1.63 A: structural and functional data that cholesterol or a cholesterol derivative is the natural ligand of RORalpha

8 July 2018

1 reference

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Transcriptional regulation of human Rev-erbalpha gene expression by the orphan nuclear receptor retinoic acid-related orphan receptor alpha

8 July 2018

1 reference

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Identification of Reverb(alpha) as a novel ROR(alpha) target gene

8 July 2018

1 reference

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Role of LXRs in control of lipogenesis

8 July 2018

1 reference

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The orphan nuclear receptor, RORalpha, regulates gene expression that controls lipid metabolism: staggerer (SG/SG) mice are resistant to diet-induced obesity.

8 July 2018

1 reference

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T0901317 is a dual LXR/FXR agonist

26 October 2018

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26 October 2018

Identifiers

DOI

10.1021/CB1002762

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16 January 2020

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16 January 2020

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