DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms (Q34793031)

4 August 2017

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title

DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms (English)

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4 August 2017

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Andrew P Feinberg

1

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4 August 2017

Hengmi Cui

series ordinal

2

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4 August 2017

Rolf Ohlsson

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3

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4 August 2017

language of work or name

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1 October 2002

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Seminars in Cancer Biology

4 August 2017

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4 August 2017

12

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4 August 2017

389-398

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4 August 2017

5

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Hypomethylation distinguishes genes of some human cancers from their normal counterparts

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Hypomethylation of DNA from benign and malignant human colon neoplasms

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

5-Azacytidine-induced undercondensations in human chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Genetic instabilities in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Cancer epigenetics takes center stage.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

An epigenetic mutation responsible for natural variation in floral symmetry

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

L-chromosome inheritance and the problem of chromosome ?imprinting? in Sciara (Sciaridae, Diptera)

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Relaxation of imprinted genes in human cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Gain of imprinting at chromosome 11p15: A pathogenetic mechanism identified in human hepatocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Insulin-like growth factor II in uterine smooth-muscle tumors: maintenance of genomic imprinting in leiomyomata and loss of imprinting in leiomyosarcomata.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Loss of imprinting in choriocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Biallelic expression of the H19 and IGF2 genes in human testicular germ cell tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Mosaic and polymorphic imprinting of the WT1 gene in humans.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Functional Polymorphism in the Parental Imprinting of the Human IGF2R Gene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Loss of Imprinting of Insulin-Like Growth Factor-II (IGF2) Gene in Distinguishing Specific Biologic Subtypes of Wilms Tumor

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Antioncogenes and human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

A general theory of carcinogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Imprinting of the gene encoding a human cyclin-dependent kinase inhibitor, p57KIP2, on chromosome 11p15

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Human KVLQT1 gene shows tissue-specific imprinting and encompasses Beckwith-Wiedemann syndrome chromosomal rearrangements.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Loss of imprinting of a paternally expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Two novel genes in the center of the 11p15 imprinted domain escape genomic imprinting

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

The two-domain hypothesis in Beckwith-Wiedemann syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

An imprinted gene p57KIP2 is mutated in Beckwith-Wiedemann syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Low frequency of p57KIP2 mutation in Beckwith-Wiedemann syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Coding mutations in p57KIP2 are present in some cases of Beckwith-Wiedemann syndrome but are rare or absent in Wilms tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Decreased expression of p57(KIP2)mRNA in human bladder cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

LIT1, an imprinted antisense RNA in the human KvLQT1 locus identified by screening for differentially expressed transcripts using monochromosomal hybrids

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith-Wiedemann syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Targeted disruption of the human LIT1 locus defines a putative imprinting control element playing an essential role in Beckwith-Wiedemann syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Disruption of an imprinted gene cluster by a targeted chromosomal translocation in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Sequence and comparative analysis of the mouse 1-megabase region orthologous to the human 11p15 imprinted domain

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Syntenic organization of the mouse distal chromosome 7 imprinting cluster and the Beckwith-Wiedemann syndrome region in chromosome 11p15.5.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Multiple mechanisms regulate imprinting of the mouse distal chromosome 7 gene cluster

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

The H19 transcript is associated with polysomes and may regulate IGF2 expression in trans.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Increased IGF-II protein affects p57kip2 expression in vivo and in vitro: implications for Beckwith-Wiedemann syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Epigenetic alterations of H19 and LIT1 distinguish patients with Beckwith-Wiedemann syndrome with cancer and birth defects

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

CpG methylation regulates the Igf2/H19 insulator

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

A differentially methylated imprinting control region within the Kcnq1 locus harbors a methylation-sensitive chromatin insulator

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Epigenetic lesions at the H19 locus in Wilms' tumour patients

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

Monoallelic expression of the human H19 gene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

A genome-wide screen for normally methylated human CpG islands that can identify novel imprinted genes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900059-7

7 January 2021

10.1016/S1044-579X(02)00059-7

Identifiers

DOI

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4 August 2017

1 reference