IL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells (Q34798580)

4 August 2017

title

IL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells (English)

1 reference

4 August 2017

Robin Parihar

1

1 reference

4 August 2017

Julie Dierksheide

series ordinal

2

1 reference

4 August 2017

Yan Hu

series ordinal

3

1 reference

4 August 2017

William E Carson

series ordinal

4

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4 August 2017

language of work or name

English

0 references

publication date

1 October 2002

1 reference

Journal of Clinical Investigation

4 August 2017

published in

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4 August 2017

volume

110

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4 August 2017

issue

7

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4 August 2017

page(s)

983-992

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The biology of human natural killer-cell subsets

4 August 2017

cites work

1 reference

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8 July 2018

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Cytokine-enhanced NK cell-mediated cytotoxicity. Positive modulatory effects of IL-2 and IL-12 on stimulus-dependent granule exocytosis.

8 July 2018

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8 July 2018

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Fc gamma R(CD16) interaction with ligand induces Ca2+ mobilization and phosphoinositide turnover in human natural killer cells. Role of Ca2+ in Fc gamma R(CD16)-induced transcription and expression of lymphokine genes

8 July 2018

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8 July 2018

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Characterization of an anti-p185HER2 monoclonal antibody that stimulates receptor function and inhibits tumor cell growth

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Upregulation of natural killer cells functions underlies the efficacy of intratumorally injected dendritic cells engineered to produce interleukin-12.

26 October 2018

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Interleukin-2 enhances the natural killer cell response to Herceptin-coated Her2/neu-positive breast cancer cells

26 October 2018

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Cytokines and soluble cytokine receptor induction after IL-12 administration in cancer patients

26 October 2018

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IL-18 and CD28 use distinct molecular mechanisms to enhance NK cell production of IL-12-induced IFN-gamma.

26 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151155

The HER-2/neu oncogene in breast cancer: prognostic factor, predictive factor, and target for therapy.

26 October 2018

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Interleukin-12 increases bispecific-antibody-mediated natural killer cell cytotoxicity against human tumors.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151155

Phosphorylation of src Family lck Tyrosine Kinase Following Interleukin-12 Activation of Human Natural Killer Cells

26 October 2018

1 reference

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Bacterial DNA-induced NK cell IFN-gamma production is dependent on macrophage secretion of IL-12

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Costimulation of T-cell proliferation by a chimeric B7-antibody fusion protein

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Clinical evaluation of the bispecific antibody MDX-H210 (anti-Fc gamma RI x anti-HER-2/neu) in combination with granulocyte-colony-stimulating factor (filgrastim) for treatment of advanced breast cancer

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Synergistic anti-tumor effects with co-expression of GM-CSF and IFN-gamma in murine tumors

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ERBB2 oncogene in human breast cancer and its clinical significance

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Immune events associated with the cure of established tumors and spontaneous metastases by local and systemic interleukin 12

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Contribution of natural killer cells to inhibition of angiogenesis by interleukin-12

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The mechanism of activation of NK-cell IFN-gamma production by ligation of CD28

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Dendritic cell-derived IL-12 promotes B cell induction of Th2 differentiation: a feedback regulation of Th1 development

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Crucial role of TNF-alpha in CD8 T cell-mediated elimination of 3LL-A9 Lewis lung carcinoma cells in vivo.

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Effects of c-erbB2 overexpression on the drug sensitivities of normal human mammary epithelial cells

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Mechanism of NK cell activation induced by coculture with dendritic cells derived from peripheral blood monocytes

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IL-18-induced expression of intercellular adhesion molecule-1 in human monocytes: involvement in IL-12 and IFN-gamma production in PBMC

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Cytokine and chemokine expression in tumors of mice receiving systemic therapy with IL-12

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Divergent phosphotyrosine signaling via Fc gamma RIIIA on human NK cells

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Phase II study of weekly intravenous recombinant humanized anti-p185HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer

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Cooperation of natural killer cell stimulatory factor/interleukin-12 with other stimuli in the induction of cytokines and cytotoxic cell-associated molecules in human T and NK cells

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Identifiers

DOI

10.1172/JCI0215950

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4 August 2017

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4 August 2017

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