The development of aggressive cancer: a possible role for sphingolipids (Q34798714)

4 August 2017

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title

The development of aggressive cancer: a possible role for sphingolipids (English)

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4 August 2017

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Norman S Radin

1

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4 August 2017

publication date

1 January 2002

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4 August 2017

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4 August 2017

volume

20

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4 August 2017

issue

5-6

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4 August 2017

page(s)

779-786

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Genetic instability and darwinian selection in tumours

4 August 2017

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Genetic instabilities in human cancers

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Advances in the signal transduction of ceramide and related sphingolipids

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Physiology and pathophysiology of sphingolipid metabolism and signaling

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Sphingolipids--the enigmatic lipid class: biochemistry, physiology, and pathophysiology

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Ganglioside GD3 and its mimetics induce cytochrome c release from mitochondria

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Apoptotic death by ceramide: will the real killer please stand up?

21 January 2018

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Molecular cloning and characterization of a human mitochondrial ceramidase

21 January 2018

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Human acid ceramidase is overexpressed but not mutated in prostate cancer

21 January 2018

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Localization of antioxidant enzymes and oxidative damage products in normal and malignant prostate epithelium

21 January 2018

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Role of gangliosides in tumour progression: a molecular target for cancer therapy?

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Sphingosine 1-phosphate signalling in mammalian cells

21 January 2018

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Occurrence of ceramides and neutral glycolipids with unusual long-chain base composition in purified rat liver mitochondria

21 January 2018

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An oncogenic role of sphingosine kinase

21 January 2018

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Chemotherapy by slowing glucosphingolipid synthesis

21 January 2018

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Sphingosine-1-phosphate and lysophosphatidic acid stimulate endothelial cell migration.

21 January 2018

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Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A. Activation is stereospecific and regulated by phosphatidic acid

21 January 2018

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Endotoxin and cytokines increase hepatic sphingolipid biosynthesis and produce lipoproteins enriched in ceramides and sphingomyelin

21 January 2018

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MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine

21 January 2018

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Retroviral transfection of Madin-Darby canine kidney cells with human MDR1 results in a major increase in globotriaosylceramide and 10(5)- to 10(6)-fold increased cell sensitivity to verocytotoxin. Role of p-glycoprotein in glycolipid synthesis

21 January 2018

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Killing cancer cells by poly-drug elevation of ceramide levels: a hypothesis whose time has come?

21 January 2018

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Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells

21 January 2018

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Neutral Glycosphingolipids and Ceramide Composition of Ethylnitrosourea-Induced Rat Neural Tumors: Accumulation of Ceramide in Tumors

21 January 2018

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Glucosylceramide synthase does not attenuate the ceramide pool accumulating during apoptosis induced by CD95 or anti-cancer regimens

21 January 2018

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Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance

21 January 2018

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Gangliosides shed by tumor cells enhance tumor formation in mice

21 January 2018

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Gangliosides Inhibit Glucosylceramide Synthase: A Possible Role in Ganglioside Therapy

21 January 2018

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Improved Inhibitors of Glucosylceramide Synthase

21 January 2018

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Ceramide Induces CytochromecRelease from Isolated Mitochondria

21 January 2018

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The role of sphingolipids in the process of signal transduction

21 January 2018

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Apoptogenic ganglioside GD3 directly induces the mitochondrial permeability transition

21 January 2018

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Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis

21 January 2018

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Ceramide Interaction with the Respiratory Chain of Heart Mitochondria†

21 January 2018

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Nitric oxide donors induce stress signaling via ceramide formation in rat renal mesangial cells

21 January 2018

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Enantioselective depletion of mitochondrial glutathione concentrations by (S)- and (R)-3-hydroxy-4-pentenoate

21 January 2018

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Compartmentalization of ceramide signaling: physical foundations and biological effects

21 January 2018

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Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-alpha-induced cell death

21 January 2018

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Differential regulation of sphingomyelinase and ceramidase activities by growth factors and cytokines. Implications for cellular proliferation and differentiation

21 January 2018

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Growth and motility of microvascular endothelium are modulated by the relative concentration of gangliosides in the medium

21 January 2018

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Redox-regulated signaling by lactosylceramide in the proliferation of human aortic smooth muscle cells

21 January 2018

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Sphingolipids in atherosclerosis and vascular biology

21 January 2018

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Regulation of UDP-glucose:ceramide glucosyltransferase-1 by ceramide

21 January 2018

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Influence of cellular ganglioside depletion on tumor formation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1081/CNV-120002495

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4 August 2017

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