CDK1-dependent inhibition of the E3 ubiquitin ligase CRL4CDT2 ensures robust transition from S Phase to Mitosis. (Q34801657)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411249%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

CDK1-dependent inhibition of the E3 ubiquitin ligase CRL4CDT2 ensures robust transition from S Phase to Mitosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411249%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1

1 reference

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23 February 2020

Jacob P Matson

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411249%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Jeanette Gowen Cook

6

1 reference

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23 February 2020

author name string

Kate E Coleman

2

1 reference

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23 February 2020

Dileep Varma

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411249%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Seeun Oh

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411249%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

English

0 references

publication date

19 November 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411249%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

23 February 2020

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

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23 February 2020

volume

290

1 reference

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23 February 2020

issue

1

1 reference

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23 February 2020

page(s)

556-567

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411249%20AND%20SRC:MED&resulttype=core&format=json

14-3-3 proteins play a role in the cell cycle by shielding cdt2 from ubiquitin-mediated degradation

23 February 2020

cites work

1 reference

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CRL4Cdt2 E3 ubiquitin ligase and proliferating cell nuclear antigen (PCNA) cooperate to degrade thymine DNA glycosylase in S phase

8 July 2018

1 reference

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Histone H4 Lys 20 monomethylation of the CENP-A nucleosome is essential for kinetochore assembly

8 July 2018

1 reference

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Thymine DNA glycosylase is a CRL4Cdt2 substrate

8 July 2018

1 reference

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p21Waf1/Cip1 deficiency causes multiple mitotic defects in tumor cells

8 July 2018

1 reference

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Identification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors

8 July 2018

1 reference

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Degradation of p12 subunit by CRL4Cdt2 E3 ligase inhibits fork progression after DNA damage

8 July 2018

1 reference

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A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase

8 July 2018

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Geminin deploys multiple mechanisms to regulate Cdt1 before cell division thus ensuring the proper execution of DNA replication

8 July 2018

1 reference

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Aurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis

8 July 2018

1 reference

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CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration

8 July 2018

1 reference

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Regulation of the CRL4(Cdt2) ubiquitin ligase and cell-cycle exit by the SCF(Fbxo11) ubiquitin ligase

8 July 2018

1 reference

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Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2.

8 July 2018

1 reference

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Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment

8 July 2018

1 reference

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Direct role for proliferating cell nuclear antigen in substrate recognition by the E3 ubiquitin ligase CRL4Cdt2.

8 July 2018

1 reference

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Common fragile sites: mechanisms of instability revisited.

8 July 2018

1 reference

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Cell cycle adaptations of embryonic stem cells

8 July 2018

1 reference

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Stress-stimulated mitogen-activated protein kinases control the stability and activity of the Cdt1 DNA replication licensing factor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

JNK1 phosphorylation of Cdt1 inhibits recruitment of HBO1 histone acetylase and blocks replication licensing in response to stress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

A public genome-scale lentiviral expression library of human ORFs

8 July 2018

1 reference

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Cdk2-dependent phosphorylation of p21 regulates the role of Cdk2 in cisplatin cytotoxicity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

CRL4Cdt2: master coordinator of cell cycle progression and genome stability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Dynamic regulation of the PR-Set7 histone methyltransferase is required for normal cell cycle progression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

CRL4Cdt2-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S Phase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation

8 July 2018

1 reference

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The p12 subunit of human polymerase delta modulates the rate and fidelity of DNA synthesis

8 July 2018

1 reference

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Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis

8 July 2018

1 reference

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Monomethylation of histone H4-lysine 20 is involved in chromosome structure and stability and is essential for mouse development

8 July 2018

1 reference

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Analysis of re-replication from deregulated origin licensing by DNA fiber spreading

8 July 2018

1 reference

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The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

PCNA-dependent regulation of p21 ubiquitylation and degradation via the CRL4Cdt2 ubiquitin ligase complex

8 July 2018

1 reference

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CDK inhibitor p21 is degraded by a proliferating cell nuclear antigen-coupled Cul4-DDB1Cdt2 pathway during S phase and after UV irradiation

8 July 2018

1 reference

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A quantitative atlas of mitotic phosphorylation

8 July 2018

1 reference

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Cdt1 and Cdc6 are destabilized by rereplication-induced DNA damage.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Regulation of APC/C activators in mitosis and meiosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

PR-Set7-dependent lysine methylation ensures genome replication and stability through S phase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Certain and progressive methylation of histone H4 at lysine 20 during the cell cycle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Cdc20: a WD40 activator for a cell cycle degradation machine

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Strength in numbers: preventing rereplication via multiple mechanisms in eukaryotic cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

The intricacies of p21 phosphorylation: protein/protein interactions, subcellular localization and stability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

PCNA is a cofactor for Cdt1 degradation by CUL4/DDB1-mediated N-terminal ubiquitination

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Proliferating human cells hypomorphic for origin recognition complex 2 and pre-replicative complex formation have a defect in p53 activation and Cdk2 kinase activation.

8 July 2018

1 reference

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Right place, right time, and only once: replication initiation in metazoans

8 July 2018

1 reference

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CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Degradation of Cdt1 during S phase is Skp2-independent and is required for efficient progression of mammalian cells through S phase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Cdt1 downregulation by proteolysis and geminin inhibition prevents DNA re-replication in Xenopus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Replication-dependent destruction of Cdt1 limits DNA replication to a single round per cell cycle in Xenopus egg extracts.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Human geminin promotes pre-RC formation and DNA replication by stabilizing CDT1 in mitosis

8 July 2018

1 reference

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Cyclin-dependent kinases phosphorylate human Cdt1 and induce its degradation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Cdt1 phosphorylation by cyclin A-dependent kinases negatively regulates its function without affecting geminin binding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

The regulated association of Cdt1 with minichromosome maintenance proteins and Cdc6 in mammalian cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

A p53-dependent checkpoint pathway prevents rereplication

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Control of DNA replication licensing in a cell cycle

8 July 2018

1 reference

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Identification of genes periodically expressed in the human cell cycle and their expression in tumors

8 July 2018

1 reference

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Analysis of Cdc6 function in the assembly of mammalian prereplication complexes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Mammalian nuclei become licensed for DNA replication during late telophase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Dynamics of DNA replication factories in living cells

8 July 2018

1 reference

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The Cdt1 protein is required to license DNA for replication in fission yeast

8 July 2018

1 reference

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XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis

8 July 2018

1 reference

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Very late DNA replication in the human cell cycle

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Geminin, an inhibitor of DNA replication, is degraded during mitosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Activation of the protein kinase p38 in the spindle assembly checkpoint and mitotic arrest.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4281756

Geminin prevents rereplication during xenopus development

8 July 2018

1 reference

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Intrinsic nuclear import activity of geminin is essential to prevent re-initiation of DNA replication in Xenopus eggs.

21 January 2018

1 reference

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MEK kinase 1 (MEKK1) transduces c-Jun NH2-terminal kinase activation in response to changes in the microtubule cytoskeleton.

21 January 2018

1 reference

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Cell cycle synchronization at the G2/M phase border by reversible inhibition of CDK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.614701

The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation

21 January 2018

1 reference

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A general method for the covalent labeling of fusion proteins with small molecules in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.614701

The spatio-temporal organization of DNA replication sites is identical in primary, immortalized and transformed mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.614701

Cyclin A-CDK activity during G1 phase impairs MCM chromatin loading and inhibits DNA synthesis in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.614701

PCNA functions as a molecular platform to trigger Cdt1 destruction and prevent re-replication

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25411249

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Segmentation and classification of cell cycle phases in fluorescence imaging

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25411249

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mammalian nuclei become licensed for DNA replication during late telophase

1 reference

2 April 2022

https://opencitations.net/index/coci/api/v1/citations/10.1242/JCS.115.1.51

Identifiers

DOI

10.1074/JBC.M114.614701

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411249%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411249%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

25411249

1 reference