Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection. (Q34804956)

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English	Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection.	scientific article

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26 January 2020

Rv3615c is a highly immunodominant RD1 (Region of Difference 1)-dependent secreted antigen specific for Mycobacterium tuberculosis infection (English)

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26 January 2020

Mycobacterium tuberculosis

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Suzie Hingley-Wilson

5

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26 January 2020

7

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26 January 2020

8

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26 January 2020

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Kerry A Millington

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26 January 2020

Sarah M Fortune

2

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26 January 2020

Jeffrey Low

3

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26 January 2020

Alejandra Garces

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26 January 2020

Melissa Wickremasinghe

6

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26 January 2020

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22 March 2011

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26 January 2020

Proceedings of the National Academy of Sciences of the United States of America

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26 January 2020

108

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26 January 2020

14

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26 January 2020

5730-5735

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26 January 2020

Secreted Immunodominant Mycobacterium tuberculosis Antigens Are Processed by the Cytosolic Pathway

1 reference

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8 July 2018

EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity

1 reference

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8 July 2018

Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guérin vaccination of newborns

1 reference

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8 July 2018

Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved

1 reference

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8 July 2018

CD4 and CD8 T-cell responses to mycobacterial antigens in African children

1 reference

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8 July 2018

The novel tuberculosis vaccine, AERAS-402, induces robust and polyfunctional CD4+ and CD8+ T cells in adults

1 reference

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8 July 2018

ESX-1 secreted virulence factors are recognized by multiple cytosolic AAA ATPases in pathogenic mycobacteria

1 reference

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Protection and polyfunctional T cells induced by Ag85B-TB10.4/IC31 against Mycobacterium tuberculosis is highly dependent on the antigen dose

1 reference

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8 July 2018

Tuberculosis vaccine research: the impact of immunology

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8 July 2018

The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle

1 reference

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8 July 2018

Multifunctional, high-level cytokine-producing Th1 cells in the lung, but not spleen, correlate with protection against Mycobacterium tuberculosis aerosol challenge in mice

1 reference

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8 July 2018

Screening of highly expressed mycobacterial genes identifies Rv3615c as a useful differential diagnostic antigen for the Mycobacterium tuberculosis complex

1 reference

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8 July 2018

T-cell quality in memory and protection: implications for vaccine design

1 reference

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8 July 2018

Improved diagnostic evaluation of suspected tuberculosis

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8 July 2018

Immunisation with BCG and recombinant MVA85A induces long-lasting, polyfunctional Mycobacterium tuberculosis-specific CD4+ memory T lymphocyte populations

1 reference

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8 July 2018

Dynamic relationship between IFN-gamma and IL-2 profile of Mycobacterium tuberculosis-specific T cells and antigen load

1 reference

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8 July 2018

Secreted proteins from Mycobacterium tuberculosis gain access to the cytosolic MHC class-I antigen-processing pathway

1 reference

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8 July 2018

Dissection of ESAT-6 system 1 of Mycobacterium tuberculosis and impact on immunogenicity and virulence

1 reference

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8 July 2018

A non-RD1 gene cluster is required for Snm secretion in Mycobacterium tuberculosis

1 reference

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8 July 2018

Mutually dependent secretion of proteins required for mycobacterial virulence.

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8 July 2018

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Evaluation of T-cell responses to novel RD1- and RD2-encoded Mycobacterium tuberculosis gene products for specific detection of human tuberculosis infection

1 reference

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8 July 2018

Individual RD1-region genes are required for export of ESAT-6/CFP-10 and for virulence of Mycobacterium tuberculosis

1 reference

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Human T cell responses to the ESAT-6 antigen from Mycobacterium tuberculosis.

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Ag85B-ESAT-6 adjuvanted with IC31 promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Classically restricted human CD8+ T lymphocytes derived from Mycobacterium tuberculosis-infected cells: definition of antigenic specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21427227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid detection of Mycobacterium tuberculosis infection by enumeration of antigen-specific T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21427227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct ex vivo analysis of antigen-specific IFN-gamma-secreting CD4 T cells in Mycobacterium tuberculosis-infected individuals: associations with clinical disease state and effect of treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/21427227

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1073/PNAS.1015153108

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Europe PubMed Central

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26 January 2020

2011PNAS..108.5730M

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26 January 2020

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26 January 2020

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