Modeling allergic asthma in mice: pitfalls and opportunities (Q34805236)

4 August 2017

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title

Modeling allergic asthma in mice: pitfalls and opportunities (English)

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4 August 2017

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Rakesh K Kumar

1

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PubMed ID

12204888

4 August 2017

Paul S Foster

series ordinal

2

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4 August 2017

1 September 2002

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American Journal of Respiratory Cell and Molecular Biology

4 August 2017

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4 August 2017

27

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4 August 2017

267-272

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4 August 2017

3

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Pharmacology of leukotriene receptor antagonists

4 August 2017

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Cytokine manipulation in animal models of asthma.

21 January 2018

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Murine models of asthma in understanding immune dysregulation in human asthma

21 January 2018

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T cells are necessary for Th2 cytokine production and eosinophil accumulation in airways of antigen-challenged allergic mice.

21 January 2018

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Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model

21 January 2018

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Interleukin-13: central mediator of allergic asthma

21 January 2018

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Requirement for IL-13 independently of IL-4 in experimental asthma

21 January 2018

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Role of vascular cell adhesion molecule 1/very late activation antigen 4 and intercellular adhesion molecule 1/lymphocyte function-associated antigen 1 interactions in antigen-induced eosinophil and T cell recruitment into the tissue

21 January 2018

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T cell-dependent regulation of eotaxin in antigen-induced pulmonary eosinophila

21 January 2018

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Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors

21 January 2018

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The importance of leukotrienes in airway inflammation in a mouse model of asthma

21 January 2018

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Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice

21 January 2018

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The coordinated action of CC chemokines in the lung orchestrates allergic inflammation and airway hyperresponsiveness

21 January 2018

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Reduction of antigen-induced airway hyperreactivity and eosinophilia in ICAM-1-deficient mice.

21 January 2018

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Cysteinyl-leukotrienes partly mediate eotaxin-induced bronchial hyperresponsiveness and eosinophilia in IL-5 transgenic mice.

21 January 2018

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Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma

21 January 2018

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Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins

21 January 2018

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Allergic eosinophil-rich inflammation develops in lungs and airways of B cell-deficient mice

21 January 2018

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Lymph node trafficking and antigen presentation by endobronchial eosinophils

21 January 2018

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Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma

21 January 2018

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Induction of airway mucus production By T helper 2 (Th2) cells: a critical role for interleukin 4 in cell recruitment but not mucus production

21 January 2018

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Signal transducer and activator of transcription factor 6 (Stat6)-deficient mice are protected from antigen-induced airway hyperresponsiveness and mucus production

21 January 2018

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IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development

21 January 2018

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Inhibition of phosphodiesterase 4 attenuates airway hyperresponsiveness and airway inflammation in a model of secondary allergen challenge

21 January 2018

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A role for cysteinyl leukotrienes in airway remodeling in a mouse asthma model

21 January 2018

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Tryptase inhibition blocks airway inflammation in a mouse asthma model

21 January 2018

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Treatment of allergic airway inflammation and hyperresponsiveness by antisense-induced local blockade of GATA-3 expression

21 January 2018

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Mouse models of allergic airway disease

21 January 2018

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Understanding the pathogenesis of allergic asthma using mouse models

21 January 2018

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Food for thought: can immunological tolerance be induced to treat asthma?

21 January 2018

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Degranulation status of airway tissue eosinophils in mouse models of allergic airway inflammation

21 January 2018

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Airway and tissue responses to antigen challenge in sensitized brown Norway rats.

21 January 2018

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Techniques for drug delivery to the airways, and the assessment of lung function in animal models

21 January 2018

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Mouse models of airway responsiveness: physiological basis of observed outcomes and analysis of selected examples using these outcome indicators

21 January 2018

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Epithelial-mesenchymal interactions in the pathogenesis of asthma

21 January 2018

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Asthma. From bronchoconstriction to airways inflammation and remodeling

21 January 2018

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Expression of interleukin 9 in the lungs of transgenic mice causes airway inflammation, mast cell hyperplasia, and bronchial hyperresponsiveness

21 January 2018

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Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production

21 January 2018

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Airway remodeling in asthma

21 January 2018

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Shifts in lung lymphocyte profiles correlate with the sequential development of acute allergic and chronic tolerant stages in a murine asthma model

21 January 2018

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Chronic airway hyperreactivity, goblet cell hyperplasia, and peribronchial fibrosis during allergic airway disease induced by Aspergillus fumigatus

21 January 2018

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Effect of acute and chronic antigen inhalation on airway morphology and responsiveness in actively sensitized rats

21 January 2018

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The effect of allergen-induced airway inflammation on airway remodeling in a murine model of allergic asthma

21 January 2018

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Prolonged allergen exposure induces structural airway changes in sensitized rats.

21 January 2018

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An improved murine model of asthma: selective airway inflammation, epithelial lesions and increased methacholine responsiveness following chronic exposure to aerosolised allergen

21 January 2018

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CD4(+) T-lymphocytes regulate airway remodeling and hyper-reactivity in a mouse model of chronic asthma.

21 January 2018

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Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment. The AMPUL Study Group

21 January 2018

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Murine model of chronic human asthma.

21 January 2018

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Pulmonary inflammation and fibrosis following subacute inhalational exposure to silica: determinants of progression

21 January 2018

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21 January 2018

Identifiers

DOI

10.1165/RCMB.F248

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4 August 2017

1 reference

PubMed ID

12204888