The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation (Q34815738)

4 August 2017

1 reference

title

The mechanism of AH receptor protein down-regulation (degradation) and its impact on AH receptor-mediated gene regulation (English)

1 reference

4 August 2017

Richard S Pollenz

1

1 reference

4 August 2017

1 September 2002

1 reference

Chemico-biological Interactions

4 August 2017

1 reference

4 August 2017

141

1 reference

4 August 2017

1-2

1 reference

4 August 2017

41-61

1 reference

Induction of cytochrome P4501A1.

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

The PAS superfamily: sensors of environmental and developmental signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Control of cell lineage-specific development and transcription by bHLH-PAS proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Characterization of polyclonal antibodies to the aromatic hydrocarbon receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Responsiveness of the adult male rat reproductive tract to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Ah receptor and ARNT expression, CYP1A1 induction, and Ah receptor down-regulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Ah receptor and ARNT protein and mRNA concentrations in rat prostate: effects of stage of development and 2,3,7, 8-tetrachlorodibenzo-p-dioxin treatment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Prolonged depletion of AH receptor without alteration of receptor mRNA levels after treatment of cells in culture with 2,3,7,8-tetrachlorodibenzo-p-dioxin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Control of gene expression by proteolysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Mdm2 promotes the rapid degradation of p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Aryl hydrocarbon receptor imported into the nucleus following ligand binding is rapidly degraded via the cytosplasmic proteasome following nuclear export

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Analysis of the complex relationship between nuclear export and aryl hydrocarbon receptor-mediated gene regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway: role of the transcription activaton and DNA binding of AhR

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Superinduction of CYP1A1 gene expression. Regulation of 2,3,7,8- tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Degradation of the basic helix-loop-helix/Per-ARNT-Sim homology domain dioxin receptor via the ubiquitin/proteasome pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Half-life of aryl hydrocarbon receptor in Hepa 1 cells: evidence for ligand-dependent alterations in cytosolic receptor levels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Crosstalk between estrogen receptor alpha and the aryl hydrocarbon receptor in breast cancer cells involves unidirectional activation of proteasomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Elevation of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) polychlorinated biphenyls. Structure-activity relationships

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Aroclor 1254 as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist: effects on enzyme induction and immunotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Dose-dependent elevation of Ah receptor binding by TCDD in rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Ah receptor in embryonic mouse palate and effects of TCDD on receptor expression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Proteasome inhibition induces nuclear translocation and transcriptional activation of the dioxin receptor in mouse embryo primary fibroblasts in the absence of xenobiotics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Proteasomes: structure and biology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Ubiquitin-mediated proteolysis: biological regulation via destruction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Modes of regulation of ubiquitin-mediated protein degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Molecular cloning and cell cycle-dependent expression of mammalian CRM1, a protein involved in nuclear export of proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Nuclear localization and export signals of the human aryl hydrocarbon receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Regulation of subcellular localization of the aryl hydrocarbon receptor (AhR).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Characterization of the AhR-hsp90-XAP2 core complex and the role of the immunophilin-related protein XAP2 in AhR stabilization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

ARA9 modifies agonist signaling through an increase in cytosolic aryl hydrocarbon receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Hepatitis B virus X-associated protein 2 is a subunit of the unliganded aryl hydrocarbon receptor core complex and exhibits transcriptional enhancer activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Disruption of the Raf-1-Hsp90 molecular complex results in destabilization of Raf-1 and loss of Raf-1-Ras association

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

The Ah receptor is a sensitive target of geldanamycin-induced protein turnover

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Down-regulation of nuclear aryl hydrocarbon receptor DNA-binding and transactivation functions: requirement for a labile or inducible factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Mutation of a protease-sensitive region in firefly luciferase alters light emission properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

A very sensitive coupled luminescent assay for cytotoxicity and complement-mediated lysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Oxygen sensing and molecular adaptation to hypoxia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

The murine Sim-2 gene product inhibits transcription by active repression and functional interference

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Possible function of Ah receptor nuclear translocator (Arnt) homodimer in transcriptional regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Constitutive function of the basic helix-loop-helix/PAS factor Arnt. Regulation of target promoters via the E box motif

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Protein kinase C modulates aryl hydrocarbon receptor nuclear translocator protein-mediated transactivation potential in a dimer context

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

ARNT-deficient mice and placental differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Characterization of 2,3,7,8-tetrachlorodibenzofuran-dependent suppression and AH receptor pathway gene expression in the developing mouse mammary gland

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

Adverse Reproductive Outcomes in the Transgenic Ah Receptor-Deficient Mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2802%2900065-0

10.1016/S0009-2797(02)00065-0

7 January 2021

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12213384