Protein kinase C-α signals P115RhoGEF phosphorylation and RhoA activation in TNF-α-induced mouse brain microvascular endothelial cell barrier dysfunction (Q34832675)

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English	Protein kinase C-α signals P115RhoGEF phosphorylation and RhoA activation in TNF-α-induced mouse brain microvascular endothelial cell barrier dysfunction	scientific article

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

Protein kinase C-α signals P115RhoGEF phosphorylation and RhoA activation in TNF-α-induced mouse brain microvascular endothelial cell barrier dysfunction (English)

1 reference

Europe PubMed Central

4 August 2017

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phosphorylation

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based on heuristic

inferred from title

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microvascular endothelial cell

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based on heuristic

inferred from title

author name string

Jing Peng

1

1 reference

Europe PubMed Central

4 August 2017

Fang He

2

1 reference

Europe PubMed Central

4 August 2017

Ciliu Zhang

3

1 reference

Europe PubMed Central

4 August 2017

Xiaolu Deng

4

1 reference

Europe PubMed Central

4 August 2017

Fei Yin

5

1 reference

Europe PubMed Central

4 August 2017

publication date

8 April 2011

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Europe PubMed Central

4 August 2017

Journal of Neuroinflammation

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Europe PubMed Central

4 August 2017

8

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Europe PubMed Central

4 August 2017

28

1 reference

Europe PubMed Central

4 August 2017

https://scigraph.springernature.com/pub.10.1186/1742-2094-8-28

0 references

Looking at the blood-brain barrier: molecular anatomy and possible investigation approaches

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Serine 34 phosphorylation of rho guanine dissociation inhibitor (RhoGDIalpha) links signaling from conventional protein kinase C to RhoGTPase in cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Rho signaling and tight junction functions

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Protein kinase Calpha: disease regulator and therapeutic target.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Zyxin is involved in thrombin signaling via interaction with PAR-1 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Molecular mechanisms of endothelial hyperpermeability: implications in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Inflammatory cytokines in vascular dysfunction and vascular disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Regulation of RhoGEF proteins by G12/13-coupled receptors

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Blood-brain barrier tight junction permeability and ischemic stroke

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8 July 2018

Protein kinase C-related kinase and ROCK are required for thrombin-induced endothelial cell permeability downstream from Galpha12/13 and Galpha11/q

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Neuroinflammation facilitates LIF entry into brain: role of TNF

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8 July 2018

The blood-brain barrier in health and chronic neurodegenerative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Blood-brain barrier: structural components and function under physiologic and pathologic conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Suppression of RhoA activity by focal adhesion kinase-induced activation of p190RhoGAP: role in regulation of endothelial permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Protein Kinase Cα-Induced p115RhoGEF Phosphorylation Signals Endothelial Cytoskeletal Rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Rho GTPases and the regulation of endothelial permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Characterization of G alpha 13-dependent plasma membrane recruitment of p115RhoGEF

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Small GTP-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

GEFs, GAPs, GDIs and effectors: taking a closer (3D) look at the regulation of Ras-related GTP-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3080812

8 July 2018

The Lsc RhoGEF mediates signaling from thromboxane A2 to actin polymerization and apoptosis in thymocytes

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-8-28

21 January 2018

Novel role of microtubules in thrombin-induced endothelial barrier dysfunction

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-8-28

21 January 2018

Direct association of RhoA with specific domains of PKC-alpha

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-8-28

21 January 2018

RhoA- and PKC-alpha-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-8-28

21 January 2018

Impaired cAMP and Rac 1 signaling contribute to TNF-alpha-induced endothelial barrier breakdown in microvascular endothelium.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-8-28

21 January 2018

Effects of Y-27632, a Rho/Rho kinase inhibitor, on leukotriene D(4)- and histamine-induced airflow obstruction and airway microvascular leakage in guinea pigs in vivo

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-8-28

21 January 2018

The permeability-reducing effects of prostacyclin and inhibition of Rho kinase do not counteract endotoxin-induced increase in permeability in cat skeletal muscle.

1 reference

https://api.crossref.org/works/10.1186%2F1742-2094-8-28

21 January 2018

Effect of lysophosphatidic acid increase the permeability of blood-brain barrier model

1 reference

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26 October 2018

Tumour necrosis factor-alpha causes an increase in blood-brain barrier permeability during sepsis.

1 reference

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26 October 2018

Lipopolysaccharide-responsive protein kinase C isotypes in the adult rat aorta.

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26 October 2018

Critical role of actin in modulating BBB permeability

1 reference

https://pubmed.ncbi.nlm.nih.gov/21473788

12 December 2020

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10.1186/1742-2094-8-28

1 reference

Europe PubMed Central

4 August 2017

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1 reference

Europe PubMed Central

4 August 2017

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Europe PubMed Central

4 August 2017

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