Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels (Q34842023)

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English	Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels	scientific article

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4 August 2017

Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels (English)

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4 August 2017

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Jurgen R. Haanstra

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Barbara Marleen Bakker

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Mark Ryten

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Dorothea Droll

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5 June 2020

Valentin Färber

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Clemetine Merce

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Christine Clayton

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15 September 2014

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Molecular Microbiology

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307-326

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5 June 2020

describes a project that uses

object named as

DESeq

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CZ Software Mentions: A large dataset of software mentions in the biomedical literature

Depletion of the Trypanosome Pumilio domain protein PUF2 or of some other essential proteins causes transcriptome changes related to coding region length

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Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks

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Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages.

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The CAF1-NOT complex of trypanosomes

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mRNA quality control goes transcriptional.

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The regulation of trypanosome gene expression by RNA-binding proteins

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Global identification of conserved post-transcriptional regulatory programs in trypanosomatids

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Gene expression is circular: factors for mRNA degradation also foster mRNA synthesis

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The roles of 3'-exoribonucleases and the exosome in trypanosome mRNA degradation

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Pyrimidine biosynthesis is not an essential function for Trypanosoma brucei bloodstream forms

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Global quantitative SILAC phosphoproteomics reveals differential phosphorylation is widespread between the procyclic and bloodstream form lifecycle stages of Trypanosoma brucei.

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8 July 2018

Complex degradation processes lead to non-exponential decay patterns and age-dependent decay rates of messenger RNA

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8 July 2018

Trypanosome CNOT10 is essential for the integrity of the NOT deadenylase complex and for degradation of many mRNAs

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Pyrimidine salvage in Trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines

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Proteome remodelling during development from blood to insect-form Trypanosoma brucei quantified by SILAC and mass spectrometry

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Extensive degradation of RNA precursors by the exosome in wild-type cells

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Genome organization is a major component of gene expression control in response to stress and during the cell division cycle in trypanosomes.

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Depletion of trypanosome CTR9 leads to gene expression defects

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Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation

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Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast

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Dual targeting of isoleucyl-tRNA synthetase in Trypanosoma brucei is mediated through alternative trans-splicing

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Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cells

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8 July 2018

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The stage-regulated expression of Leishmania mexicana CPB cysteine proteases is mediated by an intercistronic sequence element

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The Trypanosoma brucei mitochondrial ATP synthase is developmentally regulated at the level of transcript stability

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Trypanosome alternative oxidase is regulated post-transcriptionally at the level of RNA stability.

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21 January 2018

Genome-wide high-resolution mapping of exosome substrates reveals hidden features in the Arabidopsis transcriptome

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Regulated expression of glycosomal phosphoglycerate kinase in Trypanosoma brucei.

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21 January 2018

Cycloheximide-mediated accumulation of transcripts from a procyclin expression site depends on the intergenic region.

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Control and regulation of gene expression: quantitative analysis of the expression of phosphoglycerate kinase in bloodstream form Trypanosoma brucei

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21 January 2018

Proline metabolism in procyclic Trypanosoma brucei is down-regulated in the presence of glucose

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21 January 2018

Transcriptome-wide analysis of exosome targets

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21 January 2018

Transient transcriptional responses to stress are generated by opposing effects of mRNA production and degradation

1 reference

https://api.crossref.org/works/10.1111%2FMMI.12764

21 January 2018

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10.1111/MMI.12764

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145465%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145465%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145465%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

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