N-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1α/HO-1 signaling in diabetic rats (Q34852014)

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English	N-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1α/HO-1 signaling in diabetic rats	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 August 2017

N-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1α/HO-1 signaling in diabetic rats (English)

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Europe PubMed Central

PubMed publication ID

4 August 2017

1 reference

based on heuristic

inferred from title

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inferred from title

myocardial ischemia

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based on heuristic

inferred from title

Paul Michel Georges Remi Vanhoutte

10

object named as

Paul M Vanhoutte

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PubMed publication ID

4 August 2017

author name string

Xiaowen Mao

1

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4 August 2017

Tingting Wang

2

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4 August 2017

Yanan Liu

3

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4 August 2017

Michael G Irwin

4

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4 August 2017

Jing-song Ou

5

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4 August 2017

Xiao-long Liao

6

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4 August 2017

Xia Gao

7

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4 August 2017

Yuan Xu

8

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4 August 2017

Kwok F J Ng

9

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4 August 2017

Zhengyuan Xia

11

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4 August 2017

language of work or name

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publication date

18 July 2013

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Europe PubMed Central

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4 August 2017

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Europe PubMed Central

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4 August 2017

8

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Europe PubMed Central

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4 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

e68949

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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Creative Commons Attribution 4.0 International

18 July 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Hyperglycemia-induced protein kinase C β2 activation induces diastolic cardiac dysfunction in diabetic rats by impairing caveolin-3 expression and Akt/eNOS signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Activation of HIF-1 by metallothionein contributes to cardiac protection in the diabetic heart

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

NADPH oxidase inhibition ameliorates Trypanosoma cruzi-induced myocarditis during Chagas disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

N-acetylcysteine and allopurinol synergistically enhance cardiac adiponectin content and reduce myocardial reperfusion injury in diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Regulation of hypoxia-inducible factor 1 and the loss of the cellular response to hypoxia in diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Postischemic cardiac recovery in heme oxygenase-1 transgenic ischemic/reperfused mouse myocardium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Reduction of reperfusion-induced ventricular fibrillation and infarct size via heme oxygenase-1 overexpression in isolated mouse hearts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Chronic inhibition of hypoxia-inducible factor prolyl 4-hydroxylase improves ventricular performance, remodeling, and vascularity after myocardial infarction in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Effect of N-acetylcysteine on the early expression of inflammatory markers in the retina and plasma of diabetic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Xanthine oxidase inhibitor allopurinol attenuates the development of diabetic cardiomyopathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

N-acetylcysteine prevents glucose/glucose oxidase-induced oxidative stress, mitochondrial damage and apoptosis in H9c2 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Xanthine oxidoreductase in respiratory and cardiovascular disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

The effect of 2-methoxyestradiol, a HIF-1 alpha inhibitor, in global cerebral ischemia in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

HIF-1alpha induced-VEGF overexpression in bone marrow stem cells protects cardiomyocytes against ischemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Downregulation of NADPH oxidase, antioxidant enzymes, and inflammatory markers in the heart of streptozotocin-induced diabetic rats by N-acetyl-L-cysteine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Effects of triiodo-thyronine on angiotensin-induced cardiomyocyte hypertrophy: reversal of increased beta-myosin heavy chain gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Hypoxia-inducible factor as a physiological regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

The interaction between HIF-1 and AP-1 transcription factors in response to low oxygen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Enzyme estimates of infarct size correlate with functional and clinical outcomes in the setting of ST-segment elevation myocardial infarction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Myocardial ischemia and reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Myocardial infarction in diabetic rats: role of hyperglycaemia on infarct size and early expression of hypoxia-inducible factor 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Heme oxygenase: colors of defense against cellular stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3715528

8 July 2018

Risk of death or acute myocardial infarction 10 years after coronary artery bypass surgery in relation to type of diabetes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Expression of angiogenic factors during acute coronary syndromes in human type 2 diabetes

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

The role of heme oxygenase-related carbon monoxide and ventricular fibrillation in ischemic/reperfused hearts

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Hyperglycemia in streptozotocin-induced diabetic rat increases infarct size associated with low levels of myocardial HO-1 during ischemia/reperfusion.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Gene expressions of Mn-SOD and GPx-1 in streptozotocin-induced diabetes: effect of antioxidants

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Antioxidant treatment attenuates hyperglycemia-induced cardiomyocyte death in rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Effect of allopurinol on cardiomyocyte apoptosis in rats after myocardial infarction

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Xanthine oxidase is involved in free radical production in type 1 diabetes: protection by allopurinol

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

PKCβ inhibition with ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Synergy of isoflurane preconditioning and propofol postconditioning reduces myocardial reperfusion injury in patients

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Resveratrol enhances neovascularization in the infarcted rat myocardium through the induction of thioredoxin-1, heme oxygenase-1 and vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Diabetes abolishes sildenafil-induced cGMP-dependent protein kinase-I expression and cardioprotection

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

15-F(2t)-isoprostane exacerbates myocardial ischemia-reperfusion injury of isolated rat hearts

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Impact of ischemia and reperfusion times on myocardial infarct size in mice in vivo

1 reference

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21 January 2018

The effect of Ginkgo biloba in isolated ischemic/reperfused rat heart: a link between vitamin E preservation and prostaglandin biosynthesis

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Salvia miltiorrhiza treatment during early reperfusion reduced postischemic myocardial injury in the rat.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Application of high-dose propofol during ischemia improves postischemic function of rat hearts: effects on tissue antioxidant capacity

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Clinical significance of plasma free 15-F2t-isoprostane concentration during coronary artery bypasses graft surgery

1 reference

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26 October 2018

Occurrence of oxidative stress during reperfusion of the human heart

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0068949

21 January 2018

Are the antioxidant properties of carvedilol important for the protection of cardiac mitochondria?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-methoxyestradiol attenuates autophagy activation after global ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial permeability transition in the diabetic heart: contributions of thiol redox state and mitochondrial calcium to augmented reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of diabetes on early and late survival after isolated first coronary bypass surgery in multivessel disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heme oxygenase-1-related carbon monoxide production and ventricular fibrillation in isolated ischemic/reperfused mouse myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allopurinol dose is important for attenuation of liver dysfunction after normothermic ischemia: correlation between bile flow and liver enzymes in circulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Allopurinol attenuates left ventricular dysfunction in rats with early stages of streptozotocin-induced diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preconditioning protects endothelium by preventing ET-1-induced activation of NADPH oxidase and xanthine oxidase in post-ischemic heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of heme oxygenase-1 can act protectively against cardiac ischemia/reperfusion in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Ginkgo biloba extract and preconditioning on the diabetic rat myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of temporal creatine kinase-MB release and outcome after thrombolytic therapy for acute myocardial infarction. TAMI Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Postconditioning attenuates myocardial injury by reducing nitro-oxidative stress in vivo in rats and in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemic postconditioning attenuates lung reperfusion injury and reduces systemic proinflammatory cytokine release via heme oxygenase 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/23874823

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0068949

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

2013PLoSO...868949M

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

ResearchGate publication ID

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