IL-4-mediated fine tuning of IL-12p70 production by human DC. (Q34857748)

4 August 2017

IL-4-mediated fine tuning of IL-12p70 production by human DC. (English)

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4 August 2017

1

Emmanuella Guenova

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author name string

Emmanuella Guenova

1

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4 August 2017

Thomas Volz

2

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4 August 2017

Karin Sauer

3

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4 August 2017

Susanne Kaesler

4

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4 August 2017

Martin R Müller

5

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4 August 2017

Florian Wölbing

6

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4 August 2017

KoMing Chen

7

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4 August 2017

Christoph Schwärzler

8

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4 August 2017

Peter Brossart

9

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4 August 2017

Martin Röcken

10

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4 August 2017

Tilo Biedermann

11

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4 August 2017

language of work or name

English

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publication date

1 November 2008

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European Journal of Immunology

4 August 2017

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4 August 2017

38

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4 August 2017

11

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4 August 2017

3138-3149

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Human dendritic cells: potent antigen-presenting cells at the crossroads of innate and adaptive immunity

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Dendritic cells: immunobiology and cancer immunotherapy.

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Transfection of dendritic cells with RNA induces CD4- and CD8-mediated T cell immunity against breast carcinomas and reveals the immunodominance of presented T cell epitopes

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IL-12 instructs skin homing of human Th2 cells

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Steady-state and inflammatory dendritic-cell development

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Dendritic cells and the control of immunity

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Toll-dependent selection of microbial antigens for presentation by dendritic cells

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Differential antigen processing by dendritic cell subsets in vivo

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Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha

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Improved methods for the generation of dendritic cells from nonproliferating progenitors in human blood.

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Differentiation of phagocytic monocytes into lymph node dendritic cells in vivo

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Blood monocytes consist of two principal subsets with distinct migratory properties

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Langerhans cells arise from monocytes in vivo

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Monocyte-derived dendritic cells formed at the infection site control the induction of protective T helper 1 responses against Leishmania

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Antigen-specific activation, tolerization, and reactivation of the interleukin 4 pathway in vivo

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Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

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Interleukin (IL)-4 is a major regulatory cytokine governing bioactive IL-12 production by mouse and human dendritic cells

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Interleukin (IL)-4 inhibits IL-10 to promote IL-12 production by dendritic cells

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IL-4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB/c mice

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Cure of murine leishmaniasis with anti-interleukin 4 monoclonal antibody. Evidence for a T cell-dependent, interferon gamma-independent mechanism

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IL-4 Is a Mediator of IL-12p70 Induction by Human Th2 Cells: Reversal of Polarized Th2 Phenotype by Dendritic Cells

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Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis

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The role of dendritic cell subtypes in the pathophysiology of atopic dermatitis

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Cytokines and chemokines orchestrate atopic skin inflammation

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Kinetics of dendritic cell activation: impact on priming of TH1, TH2 and nonpolarized T cells

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Method for large scale isolation, culture and cryopreservation of human monocytes suitable for chemotaxis, cellular adhesion assays, macrophage and dendritic cell differentiation

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Interleukin 10 (IL-10) inhibits human lymphocyte interferon gamma-production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells

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Interleukin-12 and the regulation of innate resistance and adaptive immunity

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Characterization of a common precursor population for dendritic cells

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Origin of dendritic cells in peripheral lymphoid organs of mice.

1 reference

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Production of IL-12 by human monocyte-derived dendritic cells is optimal when the stimulus is given at the onset of maturation, and is further enhanced by IL-4

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The origin of dendritic cells

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Epidermal Langerhans cells are derived from cells originating in bone marrow

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Development of dendritic-cell lineages

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Migratory fate and differentiation of blood monocyte subsets

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Human peripheral blood dendritic cells and monocyte subsets display similar chemokine receptor expression profiles with differential migratory responses

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7 January 2021

Expression of interleukin-4 in the epidermis of transgenic mice results in a pruritic inflammatory skin disease: an experimental animal model to study atopic dermatitis.

1 reference

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A role for Th1 and Th2 cells in the immunopathogenesis of atopic dermatitis

1 reference

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Overexpression of IL-4 alters the homeostasis in the skin

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7 January 2021

Immune mechanisms leading to atopic dermatitis

1 reference

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7 January 2021

Antigen presentation to naive CD4 T cells in the lymph node.

1 reference

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Signaling and transcription in T helper development

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Self- and nonself-recognition by C-type lectins on dendritic cells

1 reference

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Dendritic cell maturation by innate lymphocytes: coordinated stimulation of innate and adaptive immunity

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7 January 2021

Immunobiology of dendritic cells

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Lesional expression of interferon-gamma in atopic eczema

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Targeting CLA/E-selectin interactions prevents CCR4-mediated recruitment of human Th2 memory cells to human skin in vivo

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Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease

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Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease

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Reversal of established delayed type hypersensitivity reactions following therapy with IL-4 or antigen-specific Th2 cells

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Roles of TH1 and TH2 cytokines in a murine model of allergic dermatitis.

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Role of CD4(+) T helper 2-type cells in cutaneous inflammatory responses induced by fluorescein isothiocyanate

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Hyperproduction of IFN-gamma by CpG oligodeoxynucleotide-induced exacerbation of atopic dermatitis-like skin lesion in some NC/Nga mice

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Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes

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Effects of anticytokine therapy in a mouse model of chronic asthma

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Evaluation of airway inflammation by quantitative Th1/Th2 cytokine mRNA measurement in sputum of asthma patients.

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Interferon-gamma as a possible target in chronic asthma

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Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells

1 reference

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7 January 2021

Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages

1 reference

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7 January 2021

Requirement for CD4 T Cell Help in Generating Functional CD8 T Cell Memory

1 reference

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Defective CD8 T Cell Memory Following Acute Infection Without CD4 T Cell Help

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7 January 2021

CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes

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The central role of CD4(+) T cells in the antitumor immune response

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Murine interleukin-4 displays potent anti-tumor activity in vivo

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T helper cell type 1-associated and cytotoxic T lymphocyte-mediated tumor immunity is impaired in interleukin 4-deficient mice

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7 January 2021

Identifiers

DOI

10.1002/EJI.200838463

1 reference

4 August 2017

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