Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets. (Q34875973)

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English	Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.	scientific article

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30 January 2020

Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets (English)

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30 January 2020

toll-like receptor

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Björn E Clausen

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Ronald N. Germain

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Ronald N Germain

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Wolfgang Kastenmüller

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Wolfgang Kastenmüller

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Kathrin Kastenmüller

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Ulrike Wille-Reece

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Ross W B Lindsay

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Lauren R Trager

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Patricia A Darrah

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Barbara J Flynn

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Maria R Becker

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Mark C Udey

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Botond Z Igyarto

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Daniel H Kaplan

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Robert A Seder

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11 April 2011

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Journal of Clinical Investigation

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1782-1796

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30 January 2020

TLR8 deficiency leads to autoimmunity in mice

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Regulation of immune cell homeostasis by type I interferons

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The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.

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Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state

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CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo.

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

8 July 2018

Natural adjuvants: endogenous activators of dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

8 July 2018

Type I interferons keep activated T cells alive

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

8 July 2018

Induction of bystander T cell proliferation by viruses and type I interferon in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

8 July 2018

Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

8 July 2018

Quantitative proteomics reveals subset-specific viral recognition in dendritic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Cutting edge: polyinosinic:polycytidylic acid boosts the generation of memory CD8 T cells through melanoma differentiation-associated protein 5 expressed in stromal cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Cutting edge: priming of CD8 T cell immunity to herpes simplex virus type 1 requires cognate TLR3 expression in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Spatial and mechanistic separation of cross-presentation and endogenous antigen presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Amine reactive dyes: an effective tool to discriminate live and dead cells in polychromatic flow cytometry.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Immunization with HIV-1 Gag protein conjugated to a TLR7/8 agonist results in the generation of HIV-1 Gag-specific Th1 and CD8+ T cell responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Dynamics and function of Langerhans cells in vivo: dermal dendritic cells colonize lymph node areas distinct from slower migrating Langerhans cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Toll-like receptor 3 promotes cross-priming to virus-infected cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Control of cross-presentation during dendritic cell maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

The Toll‐like receptor 7 (TLR7)‐specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

The immune response modifier and Toll-like receptor 7 agonist S-27609 selectively induces IL-12 and TNF-alpha production in CD11c+CD11b+CD8- dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Toll-like receptor expression in murine DC subsets: lack of TLR7 expression by CD8 alpha+ DC correlates with unresponsiveness to imidazoquinolines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Plasmacytoid dendritic cells produce cytokines and mature in response to the TLR7 agonists, imiquimod and resiquimod

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

26 October 2018

Inflammatory mediators are insufficient for full dendritic cell activation and promote expansion of CD4+ T cell populations lacking helper function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

9 December 2018

Enhanced Dendritic Cell Antigen Capture via Toll-Like Receptor-Induced Actin Remodeling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

9 December 2018

Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

9 December 2018

Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3083762

9 December 2018

Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/21540549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal and dermal dendritic cells display differential activation and migratory behavior while sharing the ability to stimulate CD4+ T cell proliferation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/21540549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of dihydropyrimidine dehydrogenase expression by real-time reverse transcription polymerase chain reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/21540549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting Edge: Intravenous Soluble Antigen Is Presented to CD4 T Cells by CD8- Dendritic Cells, but Cross-Presented to CD8 T Cells by CD8+ Dendritic Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21540549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of CCR-7, MIP-3beta , and Th-1 chemokines in type I IFN-induced monocyte-derived dendritic cells: importance for the rapid acquisition of potent migratory and functional activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/21540549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21540549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of proteasomes, transporter for antigen presentation (TAP), and beta 2-microglobulin in the processing of bacterial or particulate antigens via an alternate class I MHC processing pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/21540549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming

1 reference

https://pubmed.ncbi.nlm.nih.gov/21540549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct Stimulation of T Cells by Type I IFN Enhances the CD8+ T Cell Response during Cross-Priming

1 reference

https://pubmed.ncbi.nlm.nih.gov/21540549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-dependent selection of microbial antigens for presentation by dendritic cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21540549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of intestinal dendritic cell migration and activation by plasmacytoid dendritic cells, TNF-alpha and type 1 IFNs after feeding a TLR7/8 ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/21540549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Langerin Expressing Cells Promote Skin Immune Responses under Defined Conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/21540549

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI45416

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21540549%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21540549%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21540549%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

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