Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo. (Q34887704)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21532889%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

Metformin suppresses ovarian cancer growth and metastasis with enhancement of cisplatin cytotoxicity in vivo (English)

1 reference

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30 January 2020

0 references

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2

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30 January 2020

author name string

Ramandeep Rattan

1

1 reference

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30 January 2020

Jacie L Maguire

3

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30 January 2020

Shailendra Giri

4

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30 January 2020

Viji Shridhar

5

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30 January 2020

publication date

1 May 2011

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30 January 2020

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30 January 2020

volume

13

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30 January 2020

page(s)

483-491

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30 January 2020

issue

5

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30 January 2020

cites work

Cancer statistics, 2010

1 reference

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Metformin blocks migration and invasion of tumour cells by inhibition of matrix metalloproteinase-9 activation through a calcium and protein kinase Calpha-dependent pathway: phorbol-12-myristate-13-acetate-induced/extracellular signal-regulated [...]

8 July 2018

1 reference

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Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

Metformin: a therapeutic opportunity in breast cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

Dietary energy availability affects primary and metastatic breast cancer and metformin efficacy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

Metformin attenuates ovarian cancer cell growth in an AMP-kinase dispensable manner

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission

8 July 2018

1 reference

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In vitro metformin anti-neoplastic activity in epithelial ovarian cancer.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.

8 July 2018

1 reference

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Dose translation from animal to human studies revisited

8 July 2018

1 reference

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Current management strategies for ovarian cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

Effect of metformin on life span and on the development of spontaneous mammary tumors in HER-2/neu transgenic mice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

Glucose deprivation increases mRNA stability of vascular endothelial growth factor through activation of AMP-activated protein kinase in DU145 prostate carcinoma.

8 July 2018

1 reference

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Characterization of intraperitoneal, orthotopic, and metastatic xenograft models of human ovarian cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

Metformin blocks the stimulative effect of a high-energy diet on colon carcinoma growth in vivo and is associated with reduced expression of fatty acid synthase

8 July 2018

1 reference

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Metformin inhibits inflammatory angiogenesis in a murine sponge model

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

Metformin decreases angiogenesis via NF-kappaB and Erk1/2/Erk5 pathways by increasing the antiangiogenic thrombospondin-1.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

Metformin suppresses intestinal polyp growth in ApcMin/+ mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

Prevention of pancreatic cancer induction in hamsters by metformin

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3084625

26 October 2018

Identifiers

DOI

10.1593/NEO.11148

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21532889%20AND%20SRC:MED&resulttype=core&format=json

release_eaqxeikcsfelhikkpvl32o7yka

30 January 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/eaqxeikcsfelhikkpvl32o7yka

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

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30 January 2020

1 reference