Further understanding of the beta-globin locus regulation at the molecular level: looping or linking models? (Q34894111)

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3 December 2019

review article

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title

Further understanding of the beta-globin locus regulation at the molecular level: looping or linking models? (English)

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3 December 2019

2

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3 December 2019

author name string

Yi Tang

series ordinal

1

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3 December 2019

Chih-Chuan Liang

series ordinal

3

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3 December 2019

publication date

1 September 2002

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3 December 2019

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3 December 2019

volume

7

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3 December 2019

issue

9

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3 December 2019

page(s)

889-900

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Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter

3 December 2019

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Stopped at the border: boundaries and insulators

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Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control region.

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Targeted deletion of 5'HS1 and 5'HS4 of the beta-globin locus control region reveals additive activity of the DNaseI hypersensitive sites

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Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division

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Looping versus linking: toward a model for long-distance gene activation

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ChIPs of the beta-globin locus: unraveling gene regulation within an active domain

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Hypersensitive site 2 specifies a unique function within the human beta-globin locus control region to stimulate globin gene transcription

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The effect of distance on long-range chromatin interactions

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Distant liaisons: long-range enhancer-promoter interactions in Drosophila.

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Looping, linking, and chromatin activity: new insights into beta-globin locus regulation

21 January 2018

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The beta-globin LCR is not necessary for an open chromatin structure or developmentally regulated transcription of the native mouse beta-globin locus.

21 January 2018

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A large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse beta -globin locus

21 January 2018

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Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.

21 January 2018

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A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

21 January 2018

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A developmentally stable chromatin structure in the human beta-globin gene cluster

21 January 2018

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Developmentally dynamic histone acetylation pattern of a tissue-specific chromatin domain

21 January 2018

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Nuclear relocation of a transactivator subunit precedes target gene activation.

21 January 2018

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Nuclear compartmentalization and gene activity

21 January 2018

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A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin.

21 January 2018

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Intergenic transcription and developmental remodeling of chromatin subdomains in the human beta-globin locus.

21 January 2018

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Activation by locus control regions?

21 January 2018

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The regulation of human globin gene switching

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Position-independent, high-level expression of the human beta-globin gene in transgenic mice

21 January 2018

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Acetylation of a specific promoter nucleosome accompanies activation of the epsilon-globin gene by beta-globin locus control region HS2.

21 January 2018

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Locus control regions of mammalian beta-globin gene clusters: combining phylogenetic analyses and experimental results to gain functional insights

21 January 2018

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A defined locus control region determinant links chromatin domain acetylation with long-range gene activation

21 January 2018

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Proper developmental control of human globin genes reproduced by transgenic mice containing a 160-kb BAC carrying the human beta-globin locus

21 January 2018

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Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3.

21 January 2018

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Sequences within and flanking hypersensitive sites 3 and 2 of the beta-globin locus control region required for synergistic versus additive interaction with the epsilon-globin gene promoter

21 January 2018

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Role of DNA sequences outside the cores of DNase hypersensitive sites (HSs) in functions of the beta-globin locus control region. Domain opening and synergism between HS2 and HS3.

21 January 2018

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Transcription of the HS2 enhancer toward a cis-linked gene is independent of the orientation, position, and distance of the enhancer relative to the gene

21 January 2018

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Reconstitution of human beta-globin locus control region hypersensitive sites in the absence of chromatin assembly.

21 January 2018

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The beta-globin promoter is important for recruitment of erythroid Krüppel-like factor to the locus control region in erythroid cells

21 January 2018

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Correlation between histone lysine methylation and developmental changes at the chicken beta-globin locus

21 January 2018

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Transitions in histone acetylation reveal boundaries of three separately regulated neighboring loci

21 January 2018

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A long terminal repeat of the human endogenous retrovirus ERV-9 is located in the 5' boundary area of the human beta-globin locus control region

21 January 2018

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Different central nervous system cell types display distinct and nonrandom arrangements of satellite DNA sequences

21 January 2018

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21 January 2018

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21 January 2018

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Sequences flanking hypersensitive sites of the beta-globin locus control region are required for synergistic enhancement

21 January 2018

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Developmental specificity of the interaction between the locus control region and embryonic or fetal globin genes in transgenic mice with an HS3 core deletion

21 January 2018

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The 5'HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis

21 January 2018

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Different core promoters possess distinct regulatory activities in the Drosophila embryo

21 January 2018

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RNA polymerase II elongation through chromatin

21 January 2018

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Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice

21 January 2018

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Loss of transcriptional activity of a transgene is accompanied by DNA methylation and histone deacetylation and is prevented by insulators

21 January 2018

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Intergenic transcription in the human beta-globin gene cluster

21 January 2018

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An insulator element and condensed chromatin region separate the chicken beta-globin locus from an independently regulated erythroid-specific folate receptor gene

21 January 2018

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The locus control region is necessary for gene expression in the human beta-globin locus but not the maintenance of an open chromatin structure in erythroid cells

21 January 2018

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The murine beta-globin locus control region regulates the rate of transcription but not the hyperacetylation of histones at the active genes

21 January 2018

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21 January 2018

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The language of covalent histone modifications

21 January 2018

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Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice.

21 January 2018

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Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome

21 January 2018

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Human globin locus activation region (LAR): role in temporal control

21 January 2018

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Mechanisms of developmental control of transcription in the murine alpha- and beta-globin loci

21 January 2018

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Disruption of higher-order folding by core histone acetylation dramatically enhances transcription of nucleosomal arrays by RNA polymerase III

21 January 2018

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Transcription of the hypersensitive site HS2 enhancer in erythroid cells

21 January 2018

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The "beta-like-globin" gene domain in human erythroid cells

21 January 2018

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The H3-H4 N-terminal tail domains are the primary mediators of transcription factor IIIA access to 5S DNA within a nucleosome

21 January 2018

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Global histone acetylation and deacetylation in yeast

21 January 2018

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Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA.

21 January 2018

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Insulators: many functions, many mechanisms.

21 January 2018

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Transcription complex stability and chromatin dynamics in vivo.

21 January 2018

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A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme

21 January 2018

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