Runx2-Smad signaling impacts the progression of tumor-induced bone disease (Q34898865)

5 August 2017

Runx2-Smad signaling impacts the progression of tumor-induced bone disease (English)

1 reference

5 August 2017

1 reference

7

Gary S Stein

1 reference

5 August 2017

Xuhui Zhang

1

1 reference

5 August 2017

Jacqueline Akech

2

1 reference

5 August 2017

Gillian Browne

3

1 reference

5 August 2017

Stacey Russell

4

1 reference

5 August 2017

John J Wixted

5

1 reference

5 August 2017

Janet L Stein

6

1 reference

5 August 2017

Jane B Lian

8

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5 August 2017

language of work or name

English

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publication date

5 August 2014

1 reference

International Journal of Cancer

5 August 2017

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5 August 2017

136

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5 August 2017

6

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5 August 2017

1321-1332

1 reference

describes a project that uses

5 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4289427/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Both osteopontin-c and osteopontin-b splicing isoforms exert pro-tumorigenic roles in prostate cancer cells

8 July 2018

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8 July 2018

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VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium

8 July 2018

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Scavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells

8 July 2018

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PTHrP drives breast tumor initiation, progression, and metastasis in mice and is a potential therapy target

8 July 2018

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Metastatic breast cancer cells inhibit osteoblast differentiation through the Runx2/CBFβ-dependent expression of the Wnt antagonist, sclerostin

8 July 2018

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TGF-β in the Bone Microenvironment: Role in Breast Cancer Metastases

8 July 2018

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Cancer to bone: a fatal attraction

8 July 2018

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FOXO1 inhibits Runx2 transcriptional activity and prostate cancer cell migration and invasion

8 July 2018

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MiR-203 controls proliferation, migration and invasive potential of prostate cancer cell lines.

8 July 2018

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Breast cancer metastasis to the bone: mechanisms of bone loss

8 July 2018

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Runx2 transcriptome of prostate cancer cells: insights into invasiveness and bone metastasis

8 July 2018

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Matrix metalloproteinases as master regulators of the vicious cycle of bone metastasis

8 July 2018

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Metastatic bone disease: role of transcription factors and future targets

8 July 2018

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Effects of anti-VEGF treatment duration on tumor growth, tumor regrowth, and treatment efficacy

8 July 2018

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Runx2 regulates survivin expression in prostate cancer cells

8 July 2018

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Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions

8 July 2018

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Bone sialoprotein stimulates focal adhesion-related signaling pathways: role in migration and survival of breast and prostate cancer cells

8 July 2018

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Roles of TGFbeta in metastasis

8 July 2018

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Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells

8 July 2018

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Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.

8 July 2018

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Basic mechanisms responsible for osteolytic and osteoblastic bone metastases

8 July 2018

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Ets-1 and runx2 regulate transcription of a metastatic gene, osteopontin, in murine colorectal cancer cells

8 July 2018

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Phosphorylation, acetylation and ubiquitination: the molecular basis of RUNX regulation

8 July 2018

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Vascular endothelial growth factor contributes to prostate cancer-mediated osteoblastic activity

8 July 2018

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Runx2: a master organizer of gene transcription in developing and maturing osteoblasts

8 July 2018

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The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion

8 July 2018

1 reference

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Osteoblast-derived PTHrP is a physiological regulator of bone formation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289427

Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289427

Induction of Osteoclast Differentiation by Runx2 through Receptor Activator of Nuclear Factor-κB Ligand (RANKL) and Osteoprotegerin Regulation and Partial Rescue of Osteoclastogenesis in Runx2–/– Mice by RANKL Transgene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289427

Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289427

Tissue specific regulation of VEGF expression during bone development requires Cbfa1/Runx2.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289427

Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289427

Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289427

A RUNX2/PEBP2alpha A/CBFA1 mutation displaying impaired transactivation and Smad interaction in cleidocranial dysplasia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4289427

Plasminogen activator inhibitor type-1 (PAI-1) polymorphism 4G/5G is associated with prostate cancer among men with a positive family history.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FIJC.29094

Prostate cancer expression of runt‐domain transcription factor Runx2, a key regulator of osteoblast differentiation and function

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25053011

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cancer-associated bone disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25053011

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/IJC.29094

1 reference

5 August 2017

1 reference

5 August 2017

1 reference