Non-motor and motor features in LRRK2 transgenic mice. (Q34922393)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23936174%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

Non-motor and motor features in LRRK2 transgenic mice (English)

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7 March 2020

1

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7 March 2020

author name string

Han Chi Lim

series ordinal

2

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7 March 2020

Li Zeng

series ordinal

3

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7 March 2020

Eng King Tan

series ordinal

4

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7 March 2020

language of work or name

English

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publication date

30 July 2013

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7 March 2020

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7 March 2020

volume

8

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7 March 2020

issue

7

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7 March 2020

page(s)

e70249

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Creative Commons Attribution 4.0 International

7 March 2020

copyright license

start time

30 July 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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LRRK2 knockout mice have an intact dopaminergic system but display alterations in exploratory and motor co-ordination behaviors

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Pathogenic LRRK2 mutations do not alter gene expression in cell model systems or human brain tissue

8 July 2018

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Disruption of LRRK2 does not cause specific loss of dopaminergic neurons in zebrafish

8 July 2018

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Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

8 July 2018

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Exercise is not beneficial and may accelerate symptom onset in a mouse model of Huntington's disease

8 July 2018

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Synergistic effects of environmental risk factors and gene mutations in Parkinson's disease accelerate age-related neurodegeneration

8 July 2018

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The challenge of non-motor symptoms in Parkinson's disease

8 July 2018

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Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice

8 July 2018

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Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse model

8 July 2018

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Enhanced striatal dopamine transmission and motor performance with LRRK2 overexpression in mice is eliminated by familial Parkinson's disease mutation G2019S

8 July 2018

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The MitoPark Mouse - an animal model of Parkinson's disease with impaired respiratory chain function in dopamine neurons.

8 July 2018

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Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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R1441C mutation in LRRK2 impairs dopaminergic neurotransmission in mice.

8 July 2018

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8 July 2018

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Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Impaired learning and memory in Pitx3 deficient aphakia mice: a genetic model for striatum-dependent cognitive symptoms in Parkinson's disease

8 July 2018

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Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study

8 July 2018

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8 July 2018

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Pesticide exposure exacerbates alpha-synucleinopathy in an A53T transgenic mouse model

8 July 2018

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The LRRK2 Gly2385Arg variant is associated with Parkinson's disease: genetic and functional evidence.

8 July 2018

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8 July 2018

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Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity.

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21 January 2018

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21 January 2018

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21 January 2018

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26 October 2018

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PubMed

12 December 2020

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1 reference

PubMed

12 December 2020

10.1371/JOURNAL.PONE.0070249

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23936174%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23936174%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

PubMed publication ID

23936174

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23936174%20AND%20SRC:MED&resulttype=core&format=json