The investigational agent E1210 is effective in treatment of experimental invasive candidiasis caused by resistant Candida albicans (Q34923233)

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21 February 2020

title

The investigational agent E1210 is effective in treatment of experimental invasive candidiasis caused by resistant Candida albicans (English)

1 reference

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21 February 2020

1 reference

1 reference

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Nathan Paul Wiederhold

1

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21 February 2020

10

Thomas F Patterson

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21 February 2020

2

Laura K Najvar

1 reference

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21 February 2020

5

Rosie Bocanegra

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21 February 2020

William R. Kirkpatrick

7

object named as

William R Kirkpatrick

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21 February 2020

author name string

Annette W Fothergill

3

1 reference

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21 February 2020

Dora I McCarthy

4

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21 February 2020

Marcos Olivo

6

1 reference

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21 February 2020

Michael P Everson

8

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21 February 2020

Frederick P Duncanson

9

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21 February 2020

language of work or name

English

0 references

publication date

20 October 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25331706%20AND%20SRC:MED&resulttype=core&format=json

full work available at URL

21 February 2020

number of pages

3

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based on heuristic

inferred from page(s)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291422

1 reference

21 March 2022

Antimicrobial Agents and Chemotherapy

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21 February 2020

volume

59

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21 February 2020

issue

1

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21 February 2020

page(s)

690-692

1 reference

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E1210, a new broad-spectrum antifungal, suppresses Candida albicans hyphal growth through inhibition of glycosylphosphatidylinositol biosynthesis

21 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

Activities of E1210 and comparator agents tested by CLSI and EUCAST broth microdilution methods against Fusarium and Scedosporium species identified using molecular methods

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

In vitro activity of a novel broad-spectrum antifungal, E1210, tested against Aspergillus spp. determined by CLSI and EUCAST broth microdilution methods

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

In vitro activity of E1210, a novel antifungal, against clinically important yeasts and molds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

Efficacy of oral E1210, a new broad-spectrum antifungal with a novel mechanism of action, in murine models of candidiasis, aspergillosis, and fusariosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

In vitro activity of a novel broad-spectrum antifungal, E1210, tested against Candida spp. as determined by CLSI broth microdilution method

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

Pyrosequencing to detect mutations in FKS1 that confer reduced echinocandin susceptibility in Candida albicans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

Candida albicans cell wall proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

Gene overexpression/suppression analysis of candidate virulence factors of Candida albicans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

Functional and structural diversity in the Als protein family of Candida albicans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

Has antifungal susceptibility testing come of age?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

The ALS gene family of Candida albicans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

Fluconazole treatment of Candida albicans infection in mice: does in vitro susceptibility predict in vivo response?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4291422

The cell wall architecture of Candida albicans wild-type cells and cell wall-defective mutants.

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1128%2FAAC.03944-14

Caspofungin dose escalation for invasive candidiasis due to resistant Candida albicans.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1128%2FAAC.03944-14

Pre-clinical development of antifungal susceptibility test methods for the testing of the novel antifungal agent E1210 versus Candida: comparison of CLSI and European Committee on Antimicrobial Susceptibility Testing methods

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25331706

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Comparison of anidulafungin's and fluconazole's in vivo activity in neutropenic and non-neutropenic models of invasive candidiasis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25331706

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.03944-14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25331706%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

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21 February 2020

PubMed publication ID

25331706

1 reference