Formulation development of retrocyclin 1 analog RC-101 as an anti-HIV vaginal microbicide product (Q34932706)

5 August 2017

title

Formulation development of retrocyclin 1 analog RC-101 as an anti-HIV vaginal microbicide product (English)

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5 August 2017

A B Sassi

1

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5 August 2017

M R Cost

2

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5 August 2017

A L Cole

3

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5 August 2017

A M Cole

4

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5 August 2017

D L Patton

5

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5 August 2017

P Gupta

6

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5 August 2017

L C Rohan

7

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5 August 2017

language of work or name

English

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publication date

14 February 2011

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Antimicrobial Agents and Chemotherapy

5 August 2017

published in

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5 August 2017

volume

55

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5 August 2017

issue

5

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5 August 2017

page(s)

2282-2289

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The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques

5 August 2017

cites work

1 reference

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A novel itraconazole bioadhesive film for vaginal delivery: design, optimization, and physicodynamic characterization

8 July 2018

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Vaginal drug delivery systems for HIV prevention

8 July 2018

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HIV-1 adapts to a retrocyclin with cationic amino acid substitutions that reduce fusion efficiency of gp41.

8 July 2018

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Development and characterization of bioadhesive vaginal films of sodium polystyrene sulfonate (PSS), a novel contraceptive antimicrobial agent

8 July 2018

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RC-101, a retrocyclin-1 analogue with enhanced activity against primary HIV type 1 isolates.

8 July 2018

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In vitro comparison of topical microbicides for prevention of human immunodeficiency virus type 1 transmission

8 July 2018

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New delivery systems in contraception: vaginal rings

8 July 2018

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Development pharmaceutics of microbicide formulations. Part II: formulation, evaluation, and challenges

8 July 2018

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Retrocyclin, an Antiretroviral θ-Defensin, Is a Lectin

8 July 2018

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Development pharmaceutics of microbicide formulations. Part I: preformulation considerations and challenges

8 July 2018

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Memory CD4(+) T cells are the earliest detectable human immunodeficiency virus type 1 (HIV-1)-infected cells in the female genital mucosal tissue during HIV-1 transmission in an organ culture system

8 July 2018

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Considerations and development of topical microbicides to inhibit the sexual transmission of HIV.

8 July 2018

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Microbicides to prevent heterosexual transmission of HIV: ten years down the road

8 July 2018

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Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1.

8 July 2018

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Preliminary safety and acceptability of a carrageenan gel for possible use as a vaginal microbicide

8 July 2018

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Candidate microbicides block HIV-1 infection of human immature Langerhans cells within epithelial tissue explants

8 July 2018

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A phase I study of a novel potential intravaginal microbicide, PRO 2000, in healthy sexually inactive women

8 July 2018

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8 July 2018

A vaginal fluid simulant

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Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for clindamycin phosphate

8 July 2018

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Effects of physiological fluids on physical-chemical characteristics and activity of topical vaginal microbicide products

26 October 2018

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The retrocyclin analogue RC-101 prevents human immunodeficiency virus type 1 infection of a model human cervicovaginal tissue construct

26 October 2018

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Acceptability of Praneem polyherbal vaginal tablet among HIV uninfected women & their male partners in Pune, India--Phase I study.

26 October 2018

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Measurement of anti-HIV activity of marketed vaginal products and excipients using a PBMC-based in vitro assay

26 October 2018

1 reference

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θ-Defensins Prevent HIV-1 Env-mediated Fusion by Binding gp41 and Blocking 6-Helix Bundle Formation

26 October 2018

1 reference

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Development of an in vitro organ culture model to study transmissionof HIV-1 in the female genital tract

9 December 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3088226

Preventing disease by protecting the cervix: the unexplored promise of internal vaginal barrier devices

9 December 2018

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12 December 2020

Topical Microbicides for Disease Prevention: Status and Challenges

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12 December 2020

On the diffusion of tritiated water through skin

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12 December 2020

Women's preferences for vaginal antimicrobial contraceptives. III. Choice of a formulation, applicator, and packaging

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12 December 2020

Identifiers

DOI

10.1128/AAC.01190-10

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5 August 2017

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5 August 2017

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